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Browse our ZC3H12A Proteins (ZC3H12A)

Full name:
Zinc Finger CCCH-Type Containing 12A Proteins (ZC3H12A)
On are 4 Zinc Finger CCCH-Type Containing 12A (ZC3H12A) Proteins from 4 different suppliers available. Additionally we are shipping ZC3H12A Antibodies (33) and ZC3H12A Kits (1) and many more products for this protein. A total of 41 ZC3H12A products are currently listed.
BC036563, dJ423B22.1, MCPIP, MCPIP1, RGD1306776, RP3-423B22.1
list all proteins Gene Name GeneID UniProt
Mouse ZC3H12A ZC3H12A 230738 Q5D1E7
ZC3H12A 313587 A0JPN4
ZC3H12A 80149 Q5D1E8

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ZC3H12A Proteins (ZC3H12A) by Origin

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Mouse (Murine) Zinc Finger CCCH-Type Containing 12A (ZC3H12A) interaction partners

  1. Overexpression of MCPIP1 induced apoptosis.

  2. MCPIP1 is the target of mmu-miR (show MLXIP Proteins)-27-5p.

  3. MCPIP1-MSCs also expressed increased levels of proteins involved in angiogenesis, autophagy, and induction of differentiation

  4. This studies demonstrated that MCPIP1 is an important mediator of minocycline-induced protection from brain ischemia.

  5. Data indicate that MCPIP1 (also termed Regnase-1, encoded by Zc3h12a) knockdown enhanced interleukin-17 (IL-17 (show IL17A Proteins))-mediated signaling.

  6. MCPIP expression in the ischemic myocardium protects against adverse cardiac remodeling and dysfunction following myocardial infarction

  7. both in vivo and in vitro experiments demonstrate that the transcription factors STAT6 (show STAT6 Proteins) and KLF4 (show KLF4 Proteins) implement IL-4 (show IL4 Proteins)-induced M2 polarization via the dual catalytic activities of MCPIP.

  8. Findings reveal that differential regulation of mRNAs by Regnase-1 and Roquin (show RC3H1 Proteins) depends on their translation status and enables elaborate control of inflammation.

  9. Roquin (show RC3H1 Proteins) inhibited T(H)17 cell differentiation and acted together with the endoribonuclease regnase-1 to repress target mRNA encoding the T(H)17 cell-promoting factors IL-6 (show IL6 Proteins), ICOS (show ICOS Proteins), c-Rel (show NFkBP65 Proteins), IRF4 (show IRF4 Proteins), IkappaBNS (show NFKBID Proteins) and IkappaBzeta (show NFKBIZ Proteins).

  10. MCPIP1 deficiency in mice results in severe anemia related to autoimmune mechanisms.

Human Zinc Finger CCCH-Type Containing 12A (ZC3H12A) interaction partners

  1. Regnase-1 can be induced by HMGB1 (show HMGB1 Proteins) in microglia and negatively regulates HMGB1 (show HMGB1 Proteins)-mediated neuroinflammation and neuronal toxicity

  2. findings provide novel insight into the potential targeting of MCPIP1 or autophagy in the development of potential therapeutic strategies for silicosis

  3. These findings reveal a new potential function of MCPIP1, suggesting a possible mechanism of fibrosis in pulmonary silicosis.

  4. The human conserved stem-loop structure is not sufficient for ZC3H12A-dependent degradation.

  5. expression of miR (show MLXIP Proteins)-3613-3p might be regulated by MCPIP1 by cleavage of its precursor form.

  6. Suggest that MCPIP1 may play an important role in cholesterol induced damage in endothelial cells.

  7. Findings show increased MCP1P expression in a model of Ischemia/Reperfusion Injury (I/R) and suggest a vital role for MCPIP1 in cell migration and apoptosis, resulting in increased angiogenesis and apoptosis during the late stages of I/R.

  8. In white blood cells from patients with SLE, MCPIP1 expression was elevated, and its expression correlated positively with the IFN score and negatively with the miR (show MLXIP Proteins)-146a transcript level.

  9. demonstrated induction of MCPIP1 in human fibroblasts embedded in the stress-released 3-D collagen matrix, which occurred through activation of mitogen-activated protein kinases, phosphoinositide 3-kinase, and NF-kappaB (show NFKB1 Proteins)

  10. In this review we summarize current progress regarding the specific characteristics of sequences and structures in the 3' untranslated regions of mRNAs that are recognized by tristetraproline (show ZFP36 Proteins), Roquins, and Regnase-1.

ZC3H12A Protein Profile

Protein Summary

ZC3H12A is an MCP1 (CCL2\; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.

Alternative names and synonyms associated with ZC3H12A

  • zinc finger CCCH-type containing 12A (ZC3H12A)
  • zinc finger CCCH type containing 12A (Zc3h12a)
  • BC036563 protein
  • dJ423B22.1 protein
  • MCPIP protein
  • MCPIP1 protein
  • RGD1306776 protein
  • RP3-423B22.1 protein

Protein level used designations for ZC3H12A

zinc finger CCCH-type containing 12A , MCP-1 treatment-induced protein , MCP-induced protein 1 , ribonuclease ZC3H12A , zinc finger CCCH domain-containing protein 12A , Zinc finger CCCH domain-containing protein 12A , MCP induced protein 1

419618 Gallus gallus
456757 Pan troglodytes
608211 Canis lupus familiaris
713604 Macaca mulatta
100395231 Callithrix jacchus
100461560 Pongo abelii
100481016 Ailuropoda melanoleuca
230738 Mus musculus
313587 Rattus norvegicus
80149 Homo sapiens
535344 Bos taurus
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