Browse our FABP1 Proteins (FABP1)

On www.antibodies-online.com are 45 Fatty Acid Binding Protein 1, Liver (FABP1) Proteins from 16 different suppliers available. Additionally we are shipping FABP1 Antibodies (196) and FABP1 Kits (64) and many more products for this protein. A total of 319 FABP1 products are currently listed.
Synonyms:
FABP, FABP1, Fabpl, Fabplg, L-FABP, LFABP, liver, p14, SCP, SCP.
list all proteins Gene Name GeneID UniProt
FABP1 2168 P07148
FABP1 14080 P12710
FABP1 24360 P02692

FABP1 Proteins (FABP1) by Origin

More Proteins for FABP1 Interaction Partners

Human Fatty Acid Binding Protein 1, Liver (FABP1) interaction partners

  1. Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (show PPARA Proteins), they differ markedly in genes induced. hFABP1 T94A variant is associated with altered body mass index.[review]

  2. Urinary L-FABP, NGAL (show LCN2 Proteins), Kim-1 (show HAVCR1 Proteins) and albumin (show ALB Proteins) levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.

  3. L-FABP was found to associate with VEGFR2 on membrane rafts and subsequently activate the Akt/mTOR/P70S6K/4EBP1 and Src/FAK/cdc42 pathways, which resulted in up-regulation of VEGF-A accompanied by an increase in both angiogenic potential and migration activity. L-FABP significantly promoted tumor growth and metastasis in a xenograft mouse model.

  4. In chronic kidney disease, high urinary L-FABP correlated with the development of end-stage renal disease and cardiovascular disease.

  5. In the association of SNPs in FABP1 gene with PCOS, rs2197076 was more closely associated with its main features than rs2241883 and seemed to play a more important role in the pathogenesis of PCOS.

  6. Urinary L-FABP appears to be a sensitive biomarker of acute kidney injury in patients undergoing abdominal aortic repair.

  7. Urinary levels of NGAL (show LCN2 Proteins) are more sensitive than uKIM-1 and uL-FABP (show FABP2 Proteins) levels in predicting renal scarring in vesicoureteral reflux.

  8. Loss of staining for LFABP appears to be common in hepatocellular carcinoma and may be seen in well-differentiated hepatocellular carcinoma.

  9. In this study, the effects of hepatitis B virus X protein (HBx) mediated FABP1 regulation on hepatic steatosis and the underlying mechanism were determined.

  10. compared with the rs2919872 G allele, the rs2919872 A allele reduces the transcriptional activity of FABP1 promoter, and thereby may link FABP1 gene variation to triglyceride level in humans.

Mouse (Murine) Fatty Acid Binding Protein 1, Liver (FABP1) interaction partners

  1. Lack of a significant decrease in the flux of HDL-[(3)H]CE to biliary FC or bile acids in FABP1(-/-) mice indicates the likely compensation of its function by an as yet unidentified mechanism. Taken together, these studies demonstrate that FABP1 and SCP2 facilitate the preferential movement of HDL-CEs to bile for final elimination

  2. data showed that Fabp1 gene ablation markedly diminished the impact of high-fat diet on brain endocannabinoid levels, especially in male mice

  3. Studies show that despite overall tertiary structure similarity, the hFABP1 differs significantly from rat FABP1 in secondary structure, much larger ligand binding cavity, and affinities/specificities for some ligands. Moreover, while both mouse and hFABP1 mediate ligand induction of PPARA (show PPARA Proteins), they differ markedly in genes induced.

  4. FABP1 knockout increased brain levels of arachidonic acid-containing endocannabinoids

  5. L-FABP was more important in hepatic retention of bile acids, while SCP-2/SCP-x (show SCP2 Proteins) more broadly affected biliary bile acid and phospholipid levels.

  6. These findings suggest that some of the phenotypic divergence between the two L-Fabp(-/-) lines may reflect unanticipated differences in genetic background, underscoring the importance of genetic background in phenotypic characterization.

  7. Loss of L-FABP and SCP-2 (show CRISP3 Proteins), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.

  8. L-FABP appears to function more in hepatic retention of bile acids as well as hepatic uptake and biliary secretion of HDL (show HSD11B1 Proteins)-cholesterol

  9. L-FABP is not required to channel ATGL (show PNPLA2 Proteins)-hydrolyzed FAs (show FAS Proteins) to mitochondria for beta-oxidation or the nucleus for PPAR-alpha (show PPARA Proteins) regulation

  10. Data show that combined deletion of microsomal triglyceride transfer protein (Mttp (show MTTP Proteins)) and liver fatty acid binding protein 1 (L-Fabp) are protected from lithogenic diet (LD)-induced gallstone formation.

FABP1 Protein Profile

Protein Summary

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

Alternative names and synonyms associated with FABP1

  • fatty acid binding protein 1, liver (FABP1)
  • fatty acid binding protein 1, liver (LOC100354672)
  • fatty acid binding protein 1, liver (Fabp1)
  • liver basic fatty acid binding protein (LBFABP)
  • FABP protein
  • FABP1 protein
  • Fabpl protein
  • Fabplg protein
  • L-FABP protein
  • LFABP protein
  • liver protein
  • p14 protein
  • SCP protein
  • SCP. protein

Protein level used designations for FABP1

fatty acid binding protein 1, liver , fatty acid-binding protein, liver , fafatty acid binding protein 1, liver , fatty acid-binding protein 1 , liver-type fatty acid-binding protein , 14 kDa selenium-binding protein , fatty acid binding protein liver , Z-protein , squalene- and sterol-carrier protein , fatty acid-binding protein , liver fatty acid binding protein , L-FABP , L-BABP , LB-FABP , liver basic FABP , liver bile acid-binding protein

GENE ID SPECIES
736471 Pan troglodytes
100171896 Pongo abelii
100227345 Taeniopygia guttata
100354672 Oryctolagus cuniculus
2168 Homo sapiens
14080 Mus musculus
24360 Rattus norvegicus
445535 Sus scrofa
374015 Gallus gallus
327700 Bos taurus
403619 Canis lupus familiaris
395345 Gallus gallus
Selected quality suppliers for FABP1 Proteins (FABP1)
Did you look for something else?