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Human FOXP3 ELISA Kit for Sandwich ELISA - ABIN417287
Eleftheriadis, Pissas, Karioti, Antoniadi, Antoniadis, Liakopoulos, Stefanidis: Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytes. in Journal of basic and clinical physiology and pharmacology 2013
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analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish
correlation between the expression of t-bet, stat6 (show STAT6 ELISA Kits) and foxp3 with other genes involved in Th and T(reg (show KCNH2 ELISA Kits)) responses
cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals
Postoperative increases in Foxp3+T and Tr1 cells may predict the risk of early recurrence in digestive system neoplasms.
Elevated Foxp3 protein expression was a predictive factor of outcome in oral squamous cell carcinoma and could act as a promising therapeutic target.
a possible link and synergistic role of Foxp3 and TLR4 (show TLR4 ELISA Kits) in promoting the immune escape of cervical cancer.
FOXP3 expression was most potently induced by tumours secreting higher levels of total and active TGFbeta1 (show TGFB1 ELISA Kits) and this induction could be potently counteracted with IL-21 (show IL17C ELISA Kits), restoring T cell proliferation.
Cancer-FOXP3 serves as a prognostic biomarker and a crucial determinant of immunosuppressive microenvironment via recruiting Treg cells by directly trans-activating CCL5. Therefore, cancer-FOXP3 could be used to select patients with better response to CCL5/CCR5 blockade immunotherapy.
HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 and GITR (show TNFRSF18 ELISA Kits)
data show increased levels of Treg subsets with stable as well as transient Foxp3 expression in patients with stable allograft acceptance compared to healthy controls
Results provide evidence that Foxp3 is a downstream target of p53 (show TP53 ELISA Kits) and that is sufficient to induce p21 (show CDKN1A ELISA Kits) expression, ROS (show ROS1 ELISA Kits) production and p53 (show TP53 ELISA Kits)-mediated senescence.
a novel role of FOXP3 as a tumor suppressor in T-ALL through modulation of TAL1 (show TAL1 ELISA Kits) transcriptional activity.
We can achieve possible clinical significance of lymphoma tumor microenvironments through CD11c (show ITGAX ELISA Kits) and FOXP3 immunohistochemistry stains in extranodal diffuse large B-cell lymphoma patients receiving R-CHOP (show DDIT3 ELISA Kits) therapy.
Forkhead box P3 protein (show SLC10A3 ELISA Kits) (FoxP3) acts in multimodal fashion to directly activate or repress transcription, in a context- and partner-dependent manner, to govern Treg cell phenotypes.
Membrane-bound DKK-1 (show DKK1 ELISA Kits) is a novel Foxp3 postive Treg cell derived mediator to maintain immunological tolerance in T-cell-mediated autoimmune colitis.
A384T mutation associated with autoimmune IPEX syndrome, induces a distinctive tissue-restricted inflammation by specifically impairing the ability of Treg cells to compete with pathogenic T cells
Systemic NRF2 (show NFE2L2 ELISA Kits) activation by Keap1 (show KEAP1 ELISA Kits) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.
CTLA-4 (show CTLA4 ELISA Kits) expressed by FOXP3(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.
Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (show CD4 ELISA Kits)(+) nTregs by increasing the stability of Foxp3 expression.
This study suggests that the epigenetic modification of FOXP3 gene is involved in the pathogenesis of EAE.
Foxp3 expression is unstable in transforming growth factor beta (TGF-beta)-induced Tregs (iTregs), while stable in thymus-derived Tregs (tTregs). To stabilize Foxp3 expression in iTregs, we introduced dCas9-TET1CD (dCas9 fused to the catalytic domain (CD) of ten-eleven translocation dioxygenase 1 (TET1), methylcytosine dioxygenase) and dCas9-p300CD (dCas9 fused to the CD of p300 (show NOTCH1 ELISA Kits), histone acetyltransferase (show HAT ELISA Kits)) with guide RNA.
Increased methylation of "Foxp3 promoter" in Treg cells leads to impaired Treg suppressive function in biliary atresia.
this study shows that inflammatory signals and Foxp3 balance mTORC1 signaling and glucose metabolism to control the proliferation and suppressive function of Treg cells
sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids
In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection
Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 ELISA Kits).
The expression of Foxp3 in CD4 (show CD4 ELISA Kits)(+) T cells from persistent lymphocytotic cattle was significantly increased.
There is a positive correlation between the intensity of CD25 (show IL2RA ELISA Kits) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A ELISA Kits)(+) cells.
identification of Foxp3 expression in Treg cells
These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 ELISA Kits)(+)CD25 (show IL2RA ELISA Kits)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population
The correlation of TH17-related TLR4 (show TLR4 ELISA Kits) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.
Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.
results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
forkhead box protein P3
, regulatory protein Foxp3
, forkhead box P3
, forkhead box protein P3-like
, transcription factor foxp3
, immune dysregulation, polyendocrinopathy, enteropathy, X-linked
, immunodeficiency, polyendocrinopathy, enteropathy, X-linked
, forkhead/winged helix transcription factor 3