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Human FOXP3 ELISA Kit for Sandwich ELISA - ABIN417287
Eleftheriadis, Pissas, Karioti, Antoniadi, Antoniadis, Liakopoulos, Stefanidis: Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytes. in Journal of basic and clinical physiology and pharmacology 2013
Show all 2 Pubmed References
analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish
correlation between the expression of t-bet, stat6 (show STAT6 ELISA Kits) and foxp3 with other genes involved in Th and T(reg (show KCNH2 ELISA Kits)) responses
cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals
Control of Regulatory T Cell Development by the Transcription Factor Foxp3.
FOXP3 is regulated, at least in part, by the binding of p53 (show TP53 ELISA Kits) to several binding sites in the promoter and intron regions following ultraviolet irradiation in psoriasis.
FOXP3 rs3761549 was significantly correlated with the renal allograft function.
the density of myocardial FoxP3+ cells early after heart transplantation appears to predict at least one measure of cardiac allograft vasculopathy burden after one year
Polymorphisms of FoxP3 rs5902434 and rs2232365 were associated with female recurrent respiratory papillomatosis in Koreans.
this paper reviews the role of FOXP3 in autoimmunity
High FOXP3 expression is associated with pancreatic cancer and liver metastases from colorectal cancer.
Hepatitis C virus-associated skin lesions are associated with low frequency of Foxp3+ Treg cells. They are not related to liver enzymes or viral load; however, they are associated with a more advanced gross liver insult.
Results show that the positive rates and expression levels of nestin (show NES ELISA Kits), tyrosine hydroxylase (TH (show TH ELISA Kits)), GFAP (show GFAP ELISA Kits) and IL-17 (show IL17A ELISA Kits) were significantly decreased while Foxp3 and the ratio of Foxp3/IL-17 (show IL17A ELISA Kits) were statistically elevated in BM of AML (show RUNX1 ELISA Kits) patients.
FOXP3-positive gastric adenocarcinoma patients had significantly increased overall survival and disease-free survival rates. p21 (show CDKN1A ELISA Kits) expression showed a significant positive correlation with tumoral FOXP3 expression in gastric adenocarcinoma cells.
Foxp3 Programs the Development and Function of CD4 (show CD4 ELISA Kits)+CD25 (show IL2RA ELISA Kits)+ Regulatory T Cells.
An Essential Role for Scurfin in CD4 (show CD4 ELISA Kits)+CD25 (show IL2RA ELISA Kits)+ T Regulatory Cells.
Mechanistic analysis indicated that E47 (show TCF3 ELISA Kits) activated expression of the transcription factor Spi-B (show SPIB ELISA Kits) and the suppressor of cytokine signaling 3 (SOCS3 (show SOCS3 ELISA Kits)), which both downregulated Foxp3 expression. These findings demonstrate that the balance of Id3 (show ID3 ELISA Kits) and E47 (show TCF3 ELISA Kits) controls the maintenance of Foxp3 expression in Treg cells and, thus, contributes to Treg cell plasticity.
Foxp3 expression in lung epithelial cells, and not in Treg cells, inhibited OVA- and cockroach extract-induced asthma.
Regulatory T cells have a high apoptosis rate ex vivo correlating with low c-FLIP (show CFLAR ELISA Kits) expression.
Forkhead box P3 protein (show SLC10A3 ELISA Kits) (FoxP3) acts in multimodal fashion to directly activate or repress transcription, in a context- and partner-dependent manner, to govern Treg cell phenotypes.
Membrane-bound DKK-1 (show DKK1 ELISA Kits) is a novel Foxp3 postive Treg cell derived mediator to maintain immunological tolerance in T-cell-mediated autoimmune colitis.
A384T mutation associated with autoimmune IPEX syndrome, induces a distinctive tissue-restricted inflammation by specifically impairing the ability of Treg cells to compete with pathogenic T cells
Systemic NRF2 (show NFE2L2 ELISA Kits) activation by Keap1 (show KEAP1 ELISA Kits) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.
sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids
In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection
GWAS identified a maternal variant in the upstream region of FOXP3 that was associated with infertility in repeat-breeding Japanese Black cattle that failed to conceive using embryo transfer. The variant affected the level of FOXP3 mRNA expression.
Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 ELISA Kits).
The expression of Foxp3 in CD4 (show CD4 ELISA Kits)(+) T cells from persistent lymphocytotic cattle was significantly increased.
There is a positive correlation between the intensity of CD25 (show IL2RA ELISA Kits) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A ELISA Kits)(+) cells.
identification of Foxp3 expression in Treg cells
These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 ELISA Kits)(+)CD25 (show IL2RA ELISA Kits)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population
The correlation of TH17-related TLR4 (show TLR4 ELISA Kits) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.
Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.
results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
forkhead box protein P3
, regulatory protein Foxp3
, forkhead box P3
, forkhead box protein P3-like
, transcription factor foxp3
, immune dysregulation, polyendocrinopathy, enteropathy, X-linked
, immunodeficiency, polyendocrinopathy, enteropathy, X-linked
, forkhead/winged helix transcription factor 3