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Browse our FOXP3 Proteins (FOXP3)

Full name:
Forkhead Box P3 Proteins (FOXP3)
On are 20 Forkhead Box P3 (FOXP3) Proteins from 9 different suppliers available. Additionally we are shipping FOXP3 Antibodies (513) and FOXP3 Kits (45) and many more products for this protein. A total of 598 FOXP3 products are currently listed.
AIID, DIETER, FOXP3, IPEX, JM2, PIDX, RGD1562112, scurfin, sf, XPID
list all proteins Gene Name GeneID UniProt
FOXP3 50943 Q9BZS1
FOXP3 20371 Q99JB6
FOXP3 317382  

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FOXP3 Proteins (FOXP3) by Origin

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Top referenced FOXP3 Proteins

  1. Human FOXP3 Protein expressed in Wheat germ - ABIN1354393 : Liu, Liu, Chen, Yang, Liu, Liu, Dugas, Tang, Zheng, Liu, Wang: FOXP3 Controls an miR-146/NF-?B Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. in Cancer research 2015 (PubMed)

  2. Human FOXP3 Protein expressed in Human - ABIN2721384 : Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: Functional characterization of Foxp3-specific spontaneous immune responses. in Leukemia 2013 (PubMed)

More Proteins for FOXP3 Interaction Partners

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

  1. analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish

  2. correlation between the expression of t-bet, stat6 (show STAT6 Proteins) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Proteins)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

  1. cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

  1. Forkhead box P3 protein (FOXP3) expression is decreased in pediatric chronic autoimmune thyroiditis (CAT) patients, and this reduction seems to be associated with vitamin D levels.

  2. The percentages of CD8 (show CD8A Proteins)(+)CD25 (show IL2RA Proteins)(+)FoxP3(brigh) Tregs correlate with mean peak expiratory flow.

  3. Polymorphisms in rs3761548 and rs3761549 of FoxP3 in our population were associated with disease susceptibility and response for IST, respectively.

  4. Increasing Forkhead box P3 promoter methylation levels may cause abnormal immune tolerance through the downregulation expression of the Forkhead box P3 protein, which in turn leads to unexplained recurrent spontaneous abortion.

  5. The function of Treg cells depends on high Foxp3 expression levels, which are regulated transcriptionally and postranscriptionally.

  6. These results suggest that the polymorphism of FOXP3 may affect tacrolimus pharmacokinetics.

  7. The Foxp3 expressed in CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(+)Foxp3(+)Tregs was correlated with the histological grade, lymph node metastasis and TNM (show ODZ1 Proteins) stage of CRC (show CALR Proteins) .The IL-10 (show IL10 Proteins) expression was correlated with the histological grade and TNM (show ODZ1 Proteins) stage. The Stat3 (show STAT3 Proteins) expression was correlated with the lymph node metastasis and TNM (show ODZ1 Proteins) stage

  8. The quantitative trait loci analysis revealed a significant gender effect of the FoxP3 promoter polymorphism rs3761548A/C on miR (show MLXIP Proteins)-221, miR (show MLXIP Proteins)-222 and miR (show MLXIP Proteins)-532 expression levels, and of the FoxP3 polymorphism rs2232365A/G on miR (show MLXIP Proteins)-221 expression levels in peripheral leukocytes of rheumatoid arthritis patients.

  9. The frequency of FOXP3+CD8 (show CD8A Proteins)+ Treg was variable, without a statistically significant association with age or EBV status.

  10. this study show that FoxP3 polymorphisms could be a potential contributor for the development of preeclampsia in Iranian women

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

  1. this study shows that pretreatment with sodium selenite prevents experimental colitis by restoring Foxp3 excretion

  2. Study highlights the importance of IL-23R (show IL23R Proteins) expression level and the instability of Foxp3+ regulatory T cells in the development of inflammatory bowel diseases.

  3. indirubin administration effectively suppressed CD4 (show CD4 Proteins)(+) T cell infiltration in the colon of DSS (show PMP22 Proteins)-induced UC mice and promoted the generation of Foxp3-expressing regulatory T cells

  4. The data suggest that RORgt expression in Tregs contributes to an optimal suppressive capacity during gut (show GUSB Proteins)-specific immune responses, rendering Foxp3-RORgt T cells as an important effector Treg subset in the intestinal system.

  5. The ex vivo expression of transforming growth factor (TGF)-beta (show TGFB1 Proteins) and factor Foxp3 were significantly higher in splenocytes of the experimental mice than the basal expression observed in the control cells.

  6. These observations reveal an unexpected differential role of DJ-1 (show PARK7 Proteins) in the development of nTregs and iTregs.

  7. An IL-27 (show IL27 Proteins)/Lag3 (show LAG3 Proteins) axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.

  8. the presence of IL-2 (show IL2 Proteins) during the in vitro generation of iTreg cells confers resistance to Th17 conversion but that IL-2 (show IL2 Proteins) and retinoic acid (RA) cooperate to maintain Foxp3 expression following stimulation under Th17-polarizing conditions

  9. Foxp3 has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) pathway

  10. NZW Tregs were less sensitive to limiting doses of trophic cytokines, IL-2 (show IL2 Proteins) and -33, for population homeostasis and for maintenance of FoxP3 expression

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

  1. sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids

  2. In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

  1. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Proteins).

  2. The expression of Foxp3 in CD4 (show CD4 Proteins)(+) T cells from persistent lymphocytotic cattle was significantly increased.

  3. There is a positive correlation between the intensity of CD25 (show IL2RA Proteins) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Proteins)(+) cells.

  4. identification of Foxp3 expression in Treg cells

  5. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

  1. The correlation of TH17-related TLR4 (show TLR4 Proteins) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.

  2. Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.

  3. results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response

FOXP3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with FOXP3

  • forkhead box P3 (FOXP3)
  • forkhead box P3a (foxp3a)
  • forkhead box P3 (LOC100348270)
  • forkhead box P3 (foxp3)
  • transcription factor foxp3 (foxp3)
  • forkhead box P3 (Foxp3)
  • AIID protein
  • DIETER protein
  • FOXP3 protein
  • IPEX protein
  • JM2 protein
  • PIDX protein
  • RGD1562112 protein
  • scurfin protein
  • sf protein
  • XPID protein

Protein level used designations for Forkhead Box P3 Proteins (FOXP3)

forkhead box protein P3 , regulatory protein Foxp3 , scurfin , forkhead box P3 , forkhead box protein P3-like , transcription factor foxp3 , FOXP3delta7 , immune dysregulation, polyendocrinopathy, enteropathy, X-linked , immunodeficiency, polyendocrinopathy, enteropathy, X-linked , scurfy , forkhead/winged helix transcription factor 3

574303 Macaca mulatta
571165 Danio rerio
740909 Pan troglodytes
100037405 Felis catus
100348270 Oryctolagus cuniculus
100467988 Ailuropoda melanoleuca
100526661 Salmo salar
100158268 Xenopus laevis
50943 Homo sapiens
491876 Canis lupus familiaris
20371 Mus musculus
444998 Sus scrofa
506053 Bos taurus
317382 Rattus norvegicus
100052226 Equus caballus
100735602 Cavia porcellus
100240742 Ovis aries
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