Browse our FOXP3 Proteins (FOXP3)

Full name:
Forkhead Box P3 Proteins (FOXP3)
On are 18 Forkhead Box P3 (FOXP3) Proteins from 8 different suppliers available. Additionally we are shipping FOXP3 Antibodies (510) and FOXP3 Kits (47) and many more products for this protein. A total of 595 FOXP3 products are currently listed.
AIID, DIETER, FOXP3, IPEX, JM2, PIDX, RGD1562112, scurfin, sf, XPID
list all proteins Gene Name GeneID UniProt
FOXP3 50943 Q9BZS1
FOXP3 20371 Q99JB6
FOXP3 317382  

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FOXP3 Proteins (FOXP3) by Origin

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Top referenced FOXP3 Proteins

  1. Human FOXP3 Protein expressed in HEK-293 Cells - ABIN2721384 : Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: Functional characterization of Foxp3-specific spontaneous immune responses. in Leukemia 2013 (PubMed)

  2. Human FOXP3 Protein expressed in Wheat germ - ABIN1354393 : Liu, Liu, Chen, Yang, Liu, Liu, Dugas, Tang, Zheng, Liu, Wang: FOXP3 Controls an miR-146/NF-?B Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. in Cancer research 2015 (PubMed)

More Proteins for FOXP3 Interaction Partners

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

  1. analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish

  2. correlation between the expression of t-bet, stat6 (show STAT6 Proteins) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Proteins)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

  1. cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

  1. severe but not euthyroid Hashimoto's thyroiditis is associated with robust upregulation of T-bet and FOXP3 mRNA in peripheral T cells, independent of the thyroid hormone (show PTH Proteins) status but proportional to disease activity

  2. Results indicate that the expression of FoxP3 was not significantly associated with survival, and suggest prognostic significance of high CD68 (show CD68 Proteins) expression in primary central nervous system lymphoma (PCNSL).

  3. IL17A (show IL17A Proteins), IFNG (show IFNG Proteins), and FOXP3 are increased in plaque-type psoriasis

  4. High FOXP3 expression is associated with type 1 diabetes.

  5. Gastric adenocarcinoma patients present with increased PD-1 (show PDCD1 Proteins)(+) lymphocytes and CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(+)FOXP3(+) regulatory T cells in the peripheral blood.

  6. High FOXP3 mRNA levels correlated with larger tumor size, histological grade 3 and positive lymph-node status.

  7. We also observed a significant association between forkhead box protein 3 (show HSPB3 Proteins) ( p = 0.001) and the Neo-Bioscore, while only a marginal difference was observed with CD8 (show CD8A Proteins)+ expression ( p = 0.074). This study demonstrated that forkhead box protein 3 (show HSPB3 Proteins) expression has value as the only independent marker that predicts a good response to neoadjuvant chemotherapy and that it is related with a good prognosis according to the Neo-Biosc

  8. IDO (show IDO1 Proteins) mediated conversion of FOXP3 -T cells to Tregs predominantly occurs in children with inflammatory bowel disease.

  9. A compensatory mechanism of IL-7 (show IL7 Proteins)-mediated homeostatic proliferation can restore the inhibitory network of CD24 (show CD24 Proteins)+Foxp3+Treg cell after anti-CD25 (show IL2RA Proteins) induction therapy in islet allotransplantation.

  10. These findings demonstrate the posttranslational regulation of Foxp3 expression by AREG (show AREG Proteins) in cancer patients through AREG (show AREG Proteins)/EGFR (show EGFR Proteins)/GSK-3beta signaling, which could lead to Foxp3 protein degradation in Treg cells and a potential therapeutic target for cancer treatment.

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

  1. Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (show CD4 Proteins)(+) nTregs by increasing the stability of Foxp3 expression.

  2. This study suggests that the epigenetic modification of FOXP3 gene is involved in the pathogenesis of EAE.

  3. Foxp3 expression is unstable in transforming growth factor beta (TGF-beta)-induced Tregs (iTregs), while stable in thymus-derived Tregs (tTregs). To stabilize Foxp3 expression in iTregs, we introduced dCas9-TET1CD (dCas9 fused to the catalytic domain (CD) of ten-eleven translocation dioxygenase 1 (TET1), methylcytosine dioxygenase) and dCas9-p300CD (dCas9 fused to the CD of p300, histone acetyltransferase) with guide RNA.

  4. Increased methylation of "Foxp3 promoter" in Treg cells leads to impaired Treg suppressive function in biliary atresia.

  5. this study shows that inflammatory signals and Foxp3 balance mTORC1 signaling and glucose metabolism to control the proliferation and suppressive function of Treg cells

  6. results demonstrate that Tpl2 (show MAP3K8 Proteins) promotes inflammation in part by constraining FoxP3 expression and Treg immunosuppressive functions.

  7. Increased numbers of CD4 (show CD4 Proteins)(+)CD45RA(-)FoxP3(low) cells may cause an imbalance between Treg and Th17 cells that is mainly localized to the colon.

  8. this study shows that pretreatment with sodium selenite prevents experimental colitis by restoring Foxp3 excretion

  9. Study highlights the importance of IL-23R (show IL23R Proteins) expression level and the instability of Foxp3+ regulatory T cells in the development of inflammatory bowel diseases.

  10. indirubin administration effectively suppressed CD4 (show CD4 Proteins)(+) T cell infiltration in the colon of DSS (show PMP22 Proteins)-induced UC mice and promoted the generation of Foxp3-expressing regulatory T cells

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

  1. sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids

  2. In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

  1. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Proteins).

  2. The expression of Foxp3 in CD4 (show CD4 Proteins)(+) T cells from persistent lymphocytotic cattle was significantly increased.

  3. There is a positive correlation between the intensity of CD25 (show IL2RA Proteins) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Proteins)(+) cells.

  4. identification of Foxp3 expression in Treg cells

  5. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

  1. The correlation of TH17-related TLR4 (show TLR4 Proteins) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.

  2. Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.

  3. results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response

FOXP3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with FOXP3

  • forkhead box P3 (FOXP3)
  • forkhead box P3a (foxp3a)
  • forkhead box P3 (LOC100348270)
  • forkhead box P3 (foxp3)
  • transcription factor foxp3 (foxp3)
  • forkhead box P3 (Foxp3)
  • AIID protein
  • DIETER protein
  • FOXP3 protein
  • IPEX protein
  • JM2 protein
  • PIDX protein
  • RGD1562112 protein
  • scurfin protein
  • sf protein
  • XPID protein

Protein level used designations for Forkhead Box P3 Proteins (FOXP3)

forkhead box protein P3 , regulatory protein Foxp3 , scurfin , forkhead box P3 , forkhead box protein P3-like , transcription factor foxp3 , FOXP3delta7 , immune dysregulation, polyendocrinopathy, enteropathy, X-linked , immunodeficiency, polyendocrinopathy, enteropathy, X-linked , scurfy , forkhead/winged helix transcription factor 3

574303 Macaca mulatta
571165 Danio rerio
740909 Pan troglodytes
100037405 Felis catus
100348270 Oryctolagus cuniculus
100467988 Ailuropoda melanoleuca
100526661 Salmo salar
100158268 Xenopus laevis
50943 Homo sapiens
491876 Canis lupus familiaris
20371 Mus musculus
444998 Sus scrofa
506053 Bos taurus
317382 Rattus norvegicus
100052226 Equus caballus
100735602 Cavia porcellus
100240742 Ovis aries
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