FOXP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for FOXP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721384)
Target
See all FOXP3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This FOXP3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human FOXP3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Forkhead Box P3 (FOXP3) (AA 1-429) protein (His tag)
custom-made FOXP3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box P3 (FOXP3) (AA 1-431) protein (His tag)custom-made FOXP3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box P3 (FOXP3) (AA 1-431) protein (GST tag)FOXP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box P3 (FOXP3) (AA 1-260) protein (His tag)FOXP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).
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: "Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).
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- FOXP3 (Forkhead Box P3 (FOXP3))
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Alternative Name
- Foxp3
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Background
- The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Molecular Weight
- 47.1 kDa
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NCBI Accession
- NP_054728
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Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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