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PAF stimulation dose-dependently promoted the invasion, migration and growth of prostate cancer cells in vitro, while knockdow our findings demonstrate that PAFR (show PTAFR Proteins) can activate ERK1/2 pathway, and subsequently increase MMP-3 (show MMP3 Proteins) expression and decrease E-cadherin (show CDH1 Proteins) expression
High KIAA0101 level is associated with metastasis in hepatocellular carcinoma.
Results unveil an unsuspected role of the PAF-Wnt (show WNT2 Proteins) signalling axis in modulating cell plasticity, which is required for the maintenance of breast cancer cell stemness.
Results indicated that the expression of NS5ATP9 was up-regulated by starvation and that Beclin 1 (show BECN1 Proteins) was involved in autophagy induced in hepatoblastoma cells by starvation.
p15PAF acts as a flexible drag that regulates PCNA sliding along the DNA and facilitates the switch from replicative to translesion synthesis polymerase binding.
Data show that hepatitis C virus NS5A-transactivated protein 9 (NS5ATP9) knockdown activated mitogen-activated protein kinase kinase (show MAP2K1 Proteins)/extracellular signal regulated kinases 1/2 signaling under C virus nonstructural protein 5A (NS5A) expression.
NS5ATP9 mRNA overexpression in peripheral blood mononuclear cells was significantly associated with poor disease-free survival and overall survival of gastric cancer patients, but not with tumor recurrence.
These results highlight an important potential role for NS5ATP9 in hepatitis C virus NS5A-induced hepatocyte autophagy.
overexpression of KIAA0101 mRNA in peripheral blood mononuclear cells could act as a predictive biomarker for hepatic cancer
Upregulated expression of KIAA0101 is associated with esophageal cancer progression, resistance to chemotherapy, and poor survival.
In the aorta of SIRT1 (show SIRT1 Proteins) transgenic mice, the PAF-induced MMP-2 (show MMP2 Proteins) expression was prominently attenuated compared to that in wild type mice.
PAF-induced ductal epithelial cell hyperproliferation was accompanied by extracellular signal-regulated kinase (ERK (show EPHB2 Proteins)) phosphorylation independently of Ras or Raf (show RAF1 Proteins) mutations.
Paf as a novel and essential regulator of early hematopoiesis.
highly restricted expression of the p15(PAF) gene in a spatio-temporal manner during embryogenesis
May be involved in protection of cells from UV-induced cell death.
, PCNA-associated factor of 15 kDa
, uncharacterized protein LOC496365
, PCNA-associated factor-like
, HCV NS5A-transactivated protein 9
, hepatitis C virus NS5A-transactivated protein 9
, overexpressed in anaplastic thyroid carcinoma 1
, HCV NS5A-transactivated protein 9 homolog