Browse our MEIS1 Proteins (MEIS1)

On www.antibodies-online.com are 5 Meis Homeobox 1 (MEIS1) Proteins from 3 different suppliers available. Additionally we are shipping MEIS1 Antibodies (55) and MEIS1 Kits (1) and many more products for this protein. A total of 69 MEIS1 products are currently listed.
Synonyms:
1323/07, 1422/04, anon-EST:Liang-2.13, C530044H18Rik, cb224, CG17117, clone 2.13, Dm-HTH, Dmel\\CG17117, dtl, Evi8, Hth, hth1, hth2, id:ibd5078, l(3)05745, l(3)86Ca, meis, Meis1, meis1.1, P53, wu:fb38b03, wu:fc02e11, wu:fd12a02
list all proteins Gene Name GeneID UniProt
MEIS1 4211 O00470
MEIS1 17268 Q60954
Rat MEIS1 MEIS1 686117  

MEIS1 Proteins (MEIS1) by Origin

More Proteins for MEIS1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Meis Homeobox 1 (MEIS1) interaction partners

  1. Hth+Tsh-induced tissue overgrowth requires the BMP2 (show BMP2 Proteins) Dpp (show TGFb Proteins) and the abnormal hyperactivation of its pathway. Rather than using autocrine Dpp (show TGFb Proteins) expression, Hth+Tsh cells increase their avidity for Dpp (show TGFb Proteins), produced locally, by upregulating extracellular matrix components.

  2. the satellite repeats get transcribed in wild type embryos and that this transcription depends on the presence of Hth, which binds to them as well as to the ribosomal DNA region.

  3. The retinal determination gene Dachshund restricts cell proliferation by limiting the activity of the Homothorax-Yorkie (show YAP1 Proteins) complex

  4. Hth functions together with its co-factor Extradenticle to repress the R8-specific factor Senseless in dorsal rim area R8 cells, allowing expression of an ultraviolet-sensitive R7 Rhodopsin.

  5. Functional dissection of the splice variants of the Drosophila gene homothorax (hth

  6. Data indicate that loss of Lethal giant larvae (Lgl) tumor suppressor in the wing primordium induced epithelial neoplasia in its Homothorax (Hth)-expressing proximal domain.

  7. cooperative binding sites for En, with the homeodomain-containing Hox (show MSH2 Proteins) cofactors Extradenticle (Exd) and Homothorax (Hth) was localized, within two CRMs that drive similar expression patterns

  8. Hox (show MSH2 Proteins) genes and homothorax are required for motoneuron survival.

  9. In the flight muscles, exd and hth are genetically upstream of another muscle identity gene, salm, and are direct transcriptional regulators of the signature flight muscle structural gene, Actin88F.

  10. Loss of Ct and Hth in the antenna disc resulted in ectopic eye development in the antenna.

Human Meis Homeobox 1 (MEIS1) interaction partners

  1. results reveal that MEIS1, through induction of SYTL1 (show SYTL1 Proteins), promotes leukemogenesis and supports leukemic cell homing and engraftment, facilitating interactions between leukemic cells and bone marrow stroma.

  2. Meis1 regulates expression and activation of Syk (show SYK Proteins) in Hoxa9 (show HOXA9 Proteins)-driven leukemia.

  3. Here we present the result of a 4-stage genome-wide association study composed of 5,953 adolescent idiopathic scoliosis patients and 8,137 controls. Overall, we identified three novel susceptible loci including rs7593846 at 2p14 near MEIS1 , rs7633294 at 3p14.1 near MAGI1 (show MAGI1 Proteins) and rs9810566 at 3q26.2 near TNIK (show TNIK Proteins)

  4. Results show that Meis1 may have a positive feedback with Msi1 (show MSI1 Proteins) during the esophageal squamous cell carcinoma progression.

  5. Meis1 functions as an important regulator during the progression of acute myeloid leukemia (show BCL11A Proteins).

  6. MEIS1 drivesMalignant peripheral nerve sheath tumors cell growth via the transcription factor ID1 (show ID1 Proteins), thereby suppressing expression of the cell cycle inhibitor p27 (show PAK2 Proteins)(Kip (show CIB1 Proteins)) and maintaining cell survival.

  7. it was observed that ER stimulated gene expression by interacting with MEIS1 and FOXP3 (show FOXP3 Proteins), and ER inhibited gene expression by interacting with THRB (show THRB Proteins) and GRHL1 (show GRHL1 Proteins).

  8. this is the first report on the MEIS1 gene in esophageal squamous cell carcinoma

  9. Infant patients with acute lymphoblastic leukemia expressing low levels of MEIS1 had a superior outcome over patients expressing high levels of the protein.

  10. Our findings confirm an association between the BTBD9, MEIS1, and MAP2K5/SKOR1 SNPs and periodic limb movements of sleep in an elderly cohort.

Mouse (Murine) Meis Homeobox 1 (MEIS1) interaction partners

  1. Results show Meis1 Is expressed in normal and aberrant ducts, pancreatic intraepithelial neoplasia, and pancreatic ductal adenocarcinoma and that its expression increases cell migration in pancreatic cancer through transcriptional activation of Mcam (show MCAM Proteins).

  2. the Hoxa9 (show HOXA9 Proteins)- and Meis1-associated upregulation of Flt3 (show FLT3 Proteins) is a passive event with regard to leukemia development in mice and with limited relevance to the AML (show RUNX1 Proteins) pathology.

  3. We found that expression of Emx2 (show EMX2 Proteins) and Lhx2 (show LHX2 Proteins) initiated between neuronal progenitor and neuronal precursor stages. As far as the sensory neurons of the vomeronasal organ are concerned, Meis1 and Meis2 (show MEIS2 Proteins) were only expressed in the apical layer, together with Gnai2 (show GNAI2 Proteins), but not in the basal layer.

  4. we show that simultaneous deletion of Meis1 and Meis2 (show MEIS2 Proteins) in presumptive lens ectoderm results in arrested lens development in the pre-placodal stage, and neither lens placode nor lens is formed. We found that in the presumptive lens ectoderm of Meis1/Meis2 (show MEIS2 Proteins) deficient embryos Pax6 (show PAX6 Proteins) expression is absent

  5. Meis1 is a major regulator of sympathetic target-field innervation and Meis1 deficient sympathetic neurons die by apoptosis from early embryonic stages to perinatal stages.

  6. PCBP2 (show PCBP2 Proteins) overexpression rescues the Meis1 effects of Akt (show AKT1 Proteins)-mTOR (show FRAP1 Proteins) pathway and hypertrophy of cardiomyocytes.

  7. Data indicate roles of myeloid ecotropic viral integration site 1 protein (Meis1) in both megakaryopoiesis and erythropoiesis.

  8. Tumorigenesis by Meis1 overexpression is accompanied by a change of DNA target-sequence specificity which allows binding to the AP-1 (show JUN Proteins) element.

  9. Sequential binding of MEIS1 and NKX2-5 (show NKX2-5 Proteins) on the Popdc2 (show POPDC2 Proteins) gene demonstrate a mechanism for spatiotemporal regulation of enhancers during cardiogenesis.

  10. Pbx3 contributes to Hoxa9 (show HOXA9 Proteins) leukemogenesis through stabilization of the Meis1 protein.

Zebrafish Meis Homeobox 1 (MEIS1) interaction partners

  1. Data indicate that MiR (show MYLIP Proteins)-144 regulates primitive hematopoiesis through repression of meis1 during embryogenesis.

  2. Loss of meis1 is associated with impaired hematopoiesis as well as vascular development.

  3. This study demonistrated that Meis1 plays an important role in establishing the retinotectal map and organizing the visual system in zebrafish.

  4. The Hox (show MSH2 Proteins) cofactor Meis1 acts upstream of gata1 (show GATA1 Proteins) to regulate primitive hematopoiesis.

  5. Results implicate meis1 as a positive cell cycle regulator in early retinal cells, and provide evidence of an evolutionary conserved function for Hth/Meis genes in the maintenance of the proliferative, multipotent cell state during early eye development.

  6. These results implicate that meis1 is a novel regulator involved in endothelial cell development, presumably affecting the vegf signaling pathway.

  7. Data show that Irx7 and Irx1b are required for the proper formation and specification of rhombomeres 1 to 4, and that Irx7 functionally interacts with Meis1.1 to activate the expression of anterior hindbrain markers, such as krox20 (show EGR2 Proteins).

MEIS1 Protein Profile

Protein Summary

Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.

Alternative names and synonyms associated with MEIS1

  • Meis homeobox 1 (MEIS1)
  • Meis homeobox 1 (Meis1)
  • homothorax (hth)
  • Meis homeobox 1 (meis1)
  • myeloid ecotropic viral integration 1 (meis1)
  • 1323/07 protein
  • 1422/04 protein
  • anon-EST:Liang-2.13 protein
  • C530044H18Rik protein
  • cb224 protein
  • CG17117 protein
  • clone 2.13 protein
  • Dm-HTH protein
  • Dmel\\CG17117 protein
  • dtl protein
  • Evi8 protein
  • Hth protein
  • hth1 protein
  • hth2 protein
  • id:ibd5078 protein
  • l(3)05745 protein
  • l(3)86Ca protein
  • meis protein
  • Meis1 protein
  • meis1.1 protein
  • P53 protein
  • wu:fb38b03 protein
  • wu:fc02e11 protein
  • wu:fd12a02 protein

Protein level used designations for Meis Homeobox 1 Proteins (MEIS1)

Meis homeobox 1 , CG17117-PA , CG17117-PC , CG17117-PE , CG17117-PF , CG17117-PG , CG17117-PH , dorsotonals , gene II , hth-PA , hth-PC , hth-PE , hth-PF , hth-PG , hth-PH , homeobox protein Meis1-like , XMeis1 , XMeis1-2 protein , homeobox protein Meis1 , myeloid ecotropic viral insertion site-1a protein , Meis1, myeloid ecotropic viral integration site 1 homolog , WUGSC:H_NH0444B04.1 , leukemogenic homolog protein , myeloid ecotropic viral integration site 1 , etID37540.13

GENE ID SPECIES
769821 Gallus gallus
100329070 Saccoglossus kowalevskii
41273 Drosophila melanogaster
459288 Pan troglodytes
697685 Macaca mulatta
100338305 Oryctolagus cuniculus
100403610 Callithrix jacchus
100488182 Xenopus (Silurana) tropicalis
399305 Xenopus laevis
395589 Gallus gallus
4211 Homo sapiens
474619 Canis lupus familiaris
613877 Bos taurus
17268 Mus musculus
686117 Rattus norvegicus
100051257 Equus caballus
170446 Danio rerio
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