Browse our Myeloperoxidase Proteins (MPO)

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Myeloperoxidase Proteins (MPO)
On www.antibodies-online.com are 46 Myeloperoxidase (MPO) Proteins from 12 different suppliers available. Additionally we are shipping Myeloperoxidase Antibodies (595) and Myeloperoxidase Kits (111) and many more products for this protein. A total of 771 Myeloperoxidase products are currently listed.
Synonyms:
fj80f04, LOC100335032, mKIAA4033, MPO, wu:fj80f04
list all proteins Gene Name GeneID UniProt
MPO 4353 P05164
MPO 303413  
MPO 17523 P11247

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Myeloperoxidase Proteins (MPO) by Origin

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More Proteins for Myeloperoxidase Interaction Partners

Zebrafish Myeloperoxidase (MPO) interaction partners

  1. When infiltrated with Candida albicans, smu681 myeloperoxidase-deficient embryos and sibling embryos showed similar survival. Proliferation of C. albicans was more rapid in smu681 embryos than in sibling embryos, although it was eventually suppressed.

  2. mpx expression is controlled differently in the anterior lateral plate mesoderm and posterior lateral plate mesoderm regions and describe novel roles for etv2 (show ETV2 Proteins) and gata1 (show GATA1 Proteins) during primitive neutropoiesis.

  3. myeloperoxidase and H2O2 interact directly within neutrophils at the tissue wound

Human Myeloperoxidase (MPO) interaction partners

  1. PIC1 (show SUMO1 Proteins) inhibits the peroxidase activity of myeloperoxidase in Cystic fibrosis (show S100A8 Proteins) sputum likely via an antioxidant mechanism.

  2. In absence of CALR (show CALR Proteins), immature MPO protein precursors are degraded in the proteasome.

  3. Meta-analysis suggested an association between the MPO 463G/A polymorphism and the risk of coronary artery disease, but there is no significant association between the MPO 129G/A gene polymorphism and coronary artery disease risk.

  4. a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO, CEACAM8, CRISP3 (show CRISP3 Proteins), MS4A3 (show MS4A3 Proteins), CEACAM6, HEMGN, and MMP8 (show MMP8 Proteins)

  5. Both MPO and EPO (show EPO Proteins) are causatively involved in breast cancer progression and identified as potential therapeutic targets whereby specific novel inhibitors may reduce tumor growth and limit the occurrence of metastasis.

  6. Although IgA anti-MPO antibodies are detectable in some patients with eosinophilic granulomatosis with polyangiitis and may be detectable more frequently during active disease, their presence seems unlikely to provide information beyond what is obtained from conventional IgG anti-MPO.

  7. Clinical manifestations varied ANCA-associated vasculitis categories, and neither MPO-ANCA nor PR3-ANCA significantly affected relapse of AAV.

  8. MPO levels were higher in those patients infected with H. pylori irrespective of the virulence factors than those uninfected patients.

  9. The present study determined that ARE, CLP (show CALML3 Proteins), CAT, and MPO levels are different between the pediatric patients with sepsis and healthy controls. ARE level can be a potent biomarker for sepsis in critical patients in intensive care units.

  10. Studies of the mutants C158A, C319A, and C158A/C319A demonstrated significant differences from the wild-type protein, including diminished enzymatic activity and prevention of export to the Golgi due to prolonged association with the chaperone calnexin (show CANX Proteins). These structural and functional findings provide novel insights into MPO biosynthesis and processing.

Mouse (Murine) Myeloperoxidase (MPO) interaction partners

  1. thisa study shows that neutrophil myeloperoxidase plays a paradoxical role in bacterial clearance and tissue damage in pneumococcal acute otitis media

  2. lung MPO activity increased following induction of sepsis with CLP while siRNA treatment significantly reduced MPO activity. Liver and lung cytokine and chemokine levels in CLP-induced sepsis reduced following treatment with siRNA. These findings show a crucial pro-inflammatory role for H2S synthesized by CSE in macrophages in sepsis and suggest CSE gene silencing with siRNA as a potential therapeutic approach for this co

  3. MPO deficiency upregulates the expression of several proinflammatory cytokines and chemokines in mouse neutrophils

  4. Myeloperoxidase may be an important determinant of diet and inflammation on colon cancer risk via its effect on endogenous exposure to oxidants and acrolein.

  5. Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 (show HVCN1 Proteins) and has consequences for myeloperoxidase activity.

  6. ethanol catabolism in renal tubules results in a self-perpetuating cycle of CYP2E1 (show CYP2E1 Proteins) induction, local PTAFR (show PTAFR Proteins) ligand formation, and neutrophil infiltration and activation that leads to myeloperoxidase-dependent oxidation and damage to kidney function.

  7. These findings suggest that myeloperoxidase may contribute importantly to formation and rupture of CA.

  8. Myeloperoxidase binds to RBC (show CACNA1C Proteins) membranes in vitro and in vivo, is transported by RBCs (show SSU1 Proteins) to remote sites, and affects endothelial function as well as systemic vascular resistance.

  9. MPO knockout mice were protected from high fat diet-enhanced body weight gain and insulin (show INS Proteins) resistance. Lack of MPO also attenuated HFD-induced macrophage infiltration and expression of proinflammatory cytokines.

  10. these results demonstrate that MPO deficiency ameliorates renal injury in the renal ablation model of chronic kidney disease in mice.

Pig (Porcine) Myeloperoxidase (MPO) interaction partners

  1. the role of leukocyte activation, leukocyte-derived MPO and MPO-generated oxidants on BBB function

Horse (Equine) Myeloperoxidase (MPO) interaction partners

  1. Cycles presenting hyperedema weren't associated with high concentration of myeloperoxidase, intraluminal fluid, or positive cytology, making it a poor diagnostic tool of endometritis.

  2. The analysis of synovial fluid MPO can be used as a complementary test to aid in the discrimination between infectious and noninfectious joint disease, especially when the white blood cell counts and the total protein level are inconclusive.

  3. Results show the possibility of isolating neutrophil elastase (show ELANE Proteins) and myeloperoxidase from the same blood sample with a sufficient yield and purity for future studies on their implication and interaction during inflammatory diseases.[elastase]

  4. Slight elevation of MPO activity in the synovial fluid of horses with osteoarthritis and chronic non-septic arthritis, but greater elevation in septic arthritis.

Myeloperoxidase (MPO) Protein Profile

Protein Summary

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.

Alternative names and synonyms associated with Myeloperoxidase (MPO)

  • myeloid-specific peroxidase (mpx)
  • myeloperoxidase (MPO)
  • myeloperoxidase (LOC100335032)
  • myeloperoxidase (Mpo)
  • fj80f04 protein
  • LOC100335032 protein
  • mKIAA4033 protein
  • MPO protein
  • wu:fj80f04 protein

Protein level used designations for Myeloperoxidase Proteins (MPO)

drf , eosinophil peroxidase , myeloperoxidase , myeloperoxidase-like

GENE ID SPECIES
337514 Danio rerio
714246 Macaca mulatta
748680 Pan troglodytes
100142673 Felis catus
100335032 Ictalurus punctatus
100461693 Pongo abelii
100472895 Ailuropoda melanoleuca
100606582 Nomascus leucogenys
4353 Homo sapiens
303413 Rattus norvegicus
609986 Canis lupus familiaris
17523 Mus musculus
100517120 Sus scrofa
511206 Bos taurus
100070920 Equus caballus
100340692 Oryctolagus cuniculus
100725291 Cavia porcellus
101123053 Ovis aries
417467 Gallus gallus
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