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Browse our anti-PRMT5 (PRMT5) Antibodies

Full name:
anti-Protein Arginine Methyltransferase 5 Antibodies (PRMT5)
On are 162 Protein Arginine Methyltransferase 5 (PRMT5) Antibodies from 25 different suppliers available. Additionally we are shipping PRMT5 Proteins (8) and many more products for this protein. A total of 182 PRMT5 products are currently listed.
DDBDRAFT_0187422, DDBDRAFT_0235403, DDB_0187422, DDB_0235403, HRMT1L5, hsl7, IBP72, Jbp1, NV18830, Prmt5, si:zc14a17.2, Skb1, SKB1Hs, wu:fb95f10, zgc:110669
list all antibodies Gene Name GeneID UniProt
PRMT5 445443  
PRMT5 10419 O14744
PRMT5 27374 Q8CIG8

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Most Popular Reactivities for anti-PRMT5 (PRMT5) Antibodies

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anti-Rat (Rattus) PRMT5 Antibodies:

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anti-Mouse (Murine) PRMT5 Antibodies:

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Top referenced anti-PRMT5 Antibodies

  1. Human Polyclonal PRMT5 Primary Antibody for EIA, WB - ABIN356527 : Pal, Yun, Datta, Lacomis, Erdjument-Bromage, Kumar, Tempst, Sif: mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. in Molecular and cellular biology 2003 (PubMed)
    Show all 4 references for ABIN356527

  2. Human Polyclonal PRMT5 Primary Antibody for EIA, IHC (p) - ABIN356529 : Rho, Choi, Seong, Cho, Kim, Im: Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN356529

  3. Dog (Canine) Monoclonal PRMT5 Primary Antibody for IF, WB - ABIN968581 : Gilbreth, Yang, Bartholomeusz, Pimental, Kansra, Gadiraju, Marcus: Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 3 references for ABIN968581

  4. Human Polyclonal PRMT5 Primary Antibody for IHC (p), IHC - ABIN258206 : Pak, Lee, Roh: High nuclear expression of protein arginine methyltransferase-5 is a potentially useful marker to estimate submucosal invasion in endoscopically resected early colorectal carcinoma. in Pathology international 2015 (PubMed)

  5. Human Polyclonal PRMT5 Primary Antibody for ELISA, WB - ABIN451788 : Zhao, Rank, Tan, Li, Moritz, Simpson, Cerruti, Curtis, Patel, Allis, Cunningham, Jane: PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing. in Nature structural & molecular biology 2009 (PubMed)

  6. Chicken Polyclonal PRMT5 Primary Antibody for IHC, WB - ABIN2778654 : Azzouz, Pillai, Däpp, Chari, Meister, Kambach, Fischer, Schümperli: Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against PRMT5 Interaction Partners

Medaka Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. The results suggested that medaka Mep50 (show WDR77 Antibodies) could be a partner of Prmt5 and might play major roles in a variety of tissues in medaka.

Human Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. high expression of PRMT5 in primary and metastatic breast cancer lesions and indicated its function in cell proliferation, cell cycle progression, and apoptosis.

  2. Study showed that PRMT5 mRNA levels were significantly higher in gastric cancer (GC) tissues and were independent of tumor depth, differentiation and lymph node metastasis. Findings indicate that PRMT5 acts as an oncogene (show RAB1A Antibodies) in GC by enhancing the malignant phenotype of a cancer cell line.

  3. PRMT5 as an ASK1 (show MAP3K5 Antibodies)-binding protein.PRMT5 mediates arginine methylation of ASK1 (show MAP3K5 Antibodies).

  4. methionine adenosyltransferase II alpha (MAT2A (show MAT2A Antibodies)), and the arginine methyltransferase, PRMT5, as vulnerable enzymes in cells with MTAP (show MTAP Antibodies) deletion.

  5. Our results indicate that PRMT5 is a marker of poor prognosis in NPC (show NPC1 Antibodies) patients. PRMT5 promoted the radioresistance of NPC (show NPC1 Antibodies) cells via targeting FGFR3 (show FGFR3 Antibodies), at least partly if not totally.

  6. Data show that Omomyc protein co-localized with proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-myc (c-Myc (show MYC Antibodies)), protein arginine methyltransferase 5 (PRMT5) and histone H4 H4R3me2s-enriched chromatin domains.

  7. PRMT5 expression was upregulated during HTLV-1-mediated T-cell transformation.

  8. Increased PRMT5 activity enhanced acute myeloid leukemia (show BCL11A Antibodies) growth.

  9. arginine residues within the third intracellular loop of the D2 dopamine receptor were methylated by protein arginine methyltransferase 5 (PRMT5)

  10. high nuclear expression of Protein arginine methyltransferase-5 is a potentially useful marker for estimating submucosal invasion of early colorectal carcinomas in endoscopically resected specimens

Zebrafish Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. a combinatorial role of PRMT4/CARM1 (show CARM1 Antibodies) and PRMT5 for proper myogenesis in zebrafish

Xenopus laevis Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. Data indicate that MEP50 (show WDR77 Antibodies) WD repeat protein (show DCAF7 Antibodies) is essential for methylation of histones H4 and H2A (show H2AFX Antibodies) by PRMT5 arginine methyltransferase.

  2. data support a mechanism in which MEP50 (show WDR77 Antibodies) binds substrate and stimulates PRMT5 activity modulated by substrate post-translational modifications

  3. Protein arginine methyltransferase Prmt5-Mep50 (show WDR77 Antibodies) methylates histones H2A (show H2AFX Antibodies) and H4 and the histone chaperone nucleoplasmin (show NPM1 Antibodies) in Xenopus laevis eggs

Mouse (Murine) Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. Taken together, our data reveal a pathophysiologically relevant role for PRMT5 in MHC II transactivation in macrophages

  2. Prmt5 is required for germ cell survival during spermatogenesis in mice.

  3. Prmt5 controls proliferation of adult muscle stem cells by direct epigenetic silencing of the cell cycle inhibitor (show CDKN2A Antibodies) p21 (show D4S234E Antibodies).

  4. Prmt5 plays critical roles in germ cell development that are required for germ cell survival during embryonic stages

  5. results demonstrate that PRMT5 plays distinct roles in the behavior of HSCs compared with HPCs and is essential for the maintenance of adult hematopoietic cells.

  6. PRMT5 regulates gene expression by promoting methylation of the Sm spliceosomal proteins, but is not required for primordial germ cell specification.

  7. PRMT5 controls symmetrical dimethylation on arginine-3 of histone H4 in mouse embryonic fibroblasts.

  8. PRMT5 knockdown in non-Hodgkin lymphoma cell lines and primary lymphoma cells leads to RBL2 (show RBL2 Antibodies) derepression and RB1 (show RB1 Antibodies) reactivation, which in turn inhibit PRC2 expression.

  9. PRMT5 is a master regulator of splicing in mammals

  10. type II protein arginine methyltransferase 5 has a role in the regulation of Circadian Per1 (show PER1 Antibodies) and CRY1 (show CRY1 Antibodies) genes

Caenorhabditis elegans (C. elegans) Protein Arginine Methyltransferase 5 (PRMT5) interaction partners

  1. Analysis of prmt-5-deficient worms indicated that methylation promoted the dopamine-mediated modulation of chemosensory and locomotory behaviors through the DOP (show COPB2 Antibodies)-3 receptor.

  2. data confirm that MEP50 (show WDR77 Antibodies) plays a key role in substrate recognition and activates PRMT5 activity by increasing its affinity for protein substrates.

  3. the substrate specificity, processivity, and kinetic mechanism of bacterially expressed Caenorhabditis elegans PRMT5 (cPRMT5).

  4. analysis of structural insights into protein arginine symmetric dimethylation by PRMT5

  5. PRMT-5 represses CEP-1 transcriptional activity through CBP-1, which represents a novel regulatory mechanism of p53 (show TP53 Antibodies)-dependent apoptosis.

PRMT5 Antigen Profile

Antigen Summary

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3)\; such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR\; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity (By similarity). Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation (By similarity). Methylates HOXA9 (By similarity).

Alternative names and synonyms associated with PRMT5

  • protein arginine methyltransferase 5 (PRMT5) antibody
  • putative arginine N-methyltransferase, type II (PRMT5) antibody
  • Skb1 family protein (prmt5) antibody
  • protein arginine N-methyltransferase 5 (Prmt5) antibody
  • prmt5 protein (prmt5) antibody
  • protein arginine methyltransferase 5 (prmt5) antibody
  • HMT1 hnRNP methyltransferase-like 5 (S. cerevisiae) (Hrmt1l5) antibody
  • protein arginine methyltransferase 5 (Prmt5) antibody
  • Protein PRMT-5 (prmt-5) antibody
  • DDBDRAFT_0187422 antibody
  • DDBDRAFT_0235403 antibody
  • DDB_0187422 antibody
  • DDB_0235403 antibody
  • HRMT1L5 antibody
  • hsl7 antibody
  • IBP72 antibody
  • Jbp1 antibody
  • NV18830 antibody
  • Prmt5 antibody
  • si:zc14a17.2 antibody
  • Skb1 antibody
  • SKB1Hs antibody
  • wu:fb95f10 antibody
  • zgc:110669 antibody

Protein level used designations for PRMT5

protein arginine methyltransferase 5 , protein arginine N-methyltransferase 5 , SKB1 homolog , shk1 kinase-binding protein 1 homolog , histone-arginine N-methyltransferase PRMT5 , putative arginine N-methyltransferase, type II , protein arginine methyltransferase , protein arginine N-methyltransferase 5-like , 72 kDa ICln-binding protein , HMT1 hnRNP methyltransferase-like 5 , jak-binding protein 1 , Jak-binding protein 1

100052729 Equus caballus
100583805 Nomascus leucogenys
100173581 Pongo abelii
452789 Pan troglodytes
712718 Macaca mulatta
5068851 Leishmania infantum JPCM5
8626071 Dictyostelium discoideum AX4
100024287 Monodelphis domestica
100115766 Nasonia vitripennis
100144380 Oryzias latipes
100145788 Xenopus (Silurana) tropicalis
100357415 Oryctolagus cuniculus
100473723 Ailuropoda melanoleuca
100555438 Anolis carolinensis
445443 Rattus norvegicus
10419 Homo sapiens
368664 Danio rerio
495515 Xenopus laevis
480242 Canis lupus familiaris
100294711 Sus scrofa
515594 Bos taurus
364382 Rattus norvegicus
27374 Mus musculus
175717 Caenorhabditis elegans
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