Browse our anti-C3 (C3) Antibodies

Full name:
anti-Complement Component 3 Antibodies (C3)
On are 384 Complement Component 3 (C3) Antibodies from 21 different suppliers available. Additionally we are shipping C3 Kits (113) and C3 Proteins (42) and many more products for this protein. A total of 543 C3 products are currently listed.
AHUS5, AI255234, ARMD9, ASP, c3, C3-1, C3a, C3b, C3d, c3_D, CPAMD1, HSE-MSF, Plp, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11

All available anti-C3 Antibodies

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Top referenced anti-C3 Antibodies

  1. Human Monoclonal C3 Primary Antibody for EIA, WB - ABIN1106783 : Hartmann, Lübbers, Casaretto, Bautsch, Klos, Köhl: Rapid quantification of C3a and C5a using a combination of chromatographic and immunoassay procedures. in Journal of immunological methods 1993 (PubMed)
    Show all 4 references for 1106783

  2. Human Monoclonal C3 Primary Antibody for EIA, FACS - ABIN317012 : Janssen, Gros: Structural insights into the central complement component C3. in Molecular immunology 2006 (PubMed)
    Show all 3 references for 317012

  3. Human Monoclonal C3 Primary Antibody for EIA, WB - ABIN181105 : Hugli: Human anaphylatoxin (C3a) from the third component of complement. Primary structure. in The Journal of biological chemistry 1976 (PubMed)
    Show all 2 references for 181105

  4. Human Monoclonal C3 Primary Antibody for WB - ABIN2838577 : Ma, Li, Carreño, Patenia, Tsai, Xydes-Smith, Alousi, Champlin, Sale, Afshar-Kharghan: Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD. in Bone marrow transplantation 2014 (PubMed)
    Show all 2 references for 2838577

  5. Human Monoclonal C3 Primary Antibody for EIA, WB - ABIN1106781 : Smalley, Root, Cho, Ross, Ley: Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles. in Thrombosis and haemostasis 2007 (PubMed)
    Show all 2 references for 1106781

  6. Mouse (Murine) Monoclonal C3 Primary Antibody for EIA, FACS - ABIN114403 : Mastellos, Prechl, László, Papp, Oláh, Argyropoulos, Franchini, Tudoran, Markiewski, Lambris, Erdei: Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays. in Molecular immunology 2004 (PubMed)
    Show all 2 references for 114403

  7. Cow (Bovine) Polyclonal C3 Primary Antibody for IHC (fro), IF (p) - ABIN681913 : Trang, Hirai, Nabeta, Fuke, Yamaguchi: Membranoproliferative glomerulonephritis in a calf with nephrotic syndrome. in Journal of comparative pathology 2014 (PubMed)
    Show all 2 references for 681913

  8. Human Monoclonal C3 Primary Antibody for IHC (fro), WB - ABIN111065 : Burger, Bader, Kirschfink, Rother, Schrod, Wörner, Zilow: Functional analysis and quantification of the complement C3 derived anaphylatoxin C3a with a monoclonal antibody. in Clinical and experimental immunology 1987 (PubMed)
    Show all 2 references for 111065

  9. Mouse (Murine) Monoclonal C3 Primary Antibody for CyTOF, FACS - ABIN152429 : Maehara, Arai, Mori, Iwamura, Kurokawa, Kai, Kusunoki, Taniguchi, Ikeda, Ohara, Yamamura, Miyazaki: Circulating AIM prevents hepatocellular carcinoma through complement activation. in Cell reports 2014 (PubMed)

More Antibodies against C3 Interaction Partners

Zebrafish Complement Component 3 (C3) interaction partners

  1. Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR (show C3AR1 Antibodies), revealing an unexpected role of complement proteins in early vertebrate development.

Mouse (Murine) Complement Component 3 (C3) interaction partners

  1. Time-lapse video microscopy established the localization of the complement anaphylatoxin C3a and its receptor on enteric neural crest cells during their migration in the embryonic gut (show GUSB Antibodies). C3a plays a role in regulating collective and directional cell migration, and in ganglia network organization during enteric nervous system ontogenesis. It regulates cell migration in a N-cadherin (show CDH2 Antibodies)-dependent process.

  2. Retinal C3 was expressed by microglia/macrophages located in the outer retina in AMD (show AMD1 Antibodies) eyes. In rodent photo-oxidative damage, C3-expressing microglia/macrophages and complement activation were located in regions of lesion expansion in the outer retina over 2 months

  3. Demonstrate local synthesis of complement proteins by both PDGFRbeta-positive pericytes and CD45 (show PTPRC Antibodies)-positive cells in kidney fibrosis.

  4. Wild-type C57BL/6 mice with pristane-induced lupus developed a strong IFN signature, which was absent in immunoglobulin-deficient (muMT), C3(-/-) , and CD18 (show ITGB2 Antibodies)(-/-) mice. In vivo phagocytosis of dead cells was impaired in C3-deficient mice.

  5. Study found that cancer-cell-derived C3 activates the C3a receptor in the choroid plexus epithelium to disrupt the blood-cerebrospinal fluid (CSF (show CSF2 Antibodies)) barrier. This effect allows plasma components, including amphiregulin (show AREG Antibodies), and other mitogens to enter the CSF (show CSF2 Antibodies) and promote cancer cell growth.

  6. We induced anti-myeloperoxidase (show MPO Antibodies) vasculitis in mice and confirmed a role for complement activation by demonstrating protection in C3-deficient mice.

  7. These data indicated that alpha7-nAChR (show CHRNA7 Antibodies) caused the inhibition of ASPinduced activation of p38 (show CRK Antibodies) kinase and NFkappa B to inhibit the production of MCP1 (show CCL2 Antibodies) and keratinocytederived chemokine (show CCL1 Antibodies).

  8. This study provideed the evidence that C3a plays a critical role in cerebral endothelial activation and leukocyte recruitment during inflammation in the brain.

  9. Demonstrate that cardiac Sirt1 (show SIRT1 Antibodies) plays an essential role in caloritc restriction-induced cardioprotection against myocardial I/R injury by suppressing cardiac C3 expression.

  10. The roles of C3, CfB (show CFB Antibodies), and C3a receptor in the severity of S. aureus induced septic arthritis are reported.

Human Complement Component 3 (C3) interaction partners

  1. C3d-positive glomerular staining is an independent risk factor for the development of end-stage renal disease in ANCA-associated renal vasculitis.

  2. Factor I binds C3b-Factor H (show CFH Antibodies) between Factor H (show CFH Antibodies) domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  3. The VEGF (show VEGFA Antibodies) haplotype TGA (show TBX1 Antibodies) could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD (show AMD1 Antibodies) treated with bevacizumab.

  4. The uromodulin (show UMOD Antibodies)-CFH (show CFH Antibodies) interaction enhanced the cofactor activity of CFH (show CFH Antibodies) for factor I-mediated cleavage of C3b to inactivated C3b.

  5. Generated monoclonal antibody that can only bind to C3d when it manifests itself as the final end product of cleaved C3.

  6. C3 was strongly associated with insulin (show INS Antibodies) sensitivity after bariatric surgery.

  7. human neutrophil peptides 1-3 and complement activation fragments iC3b were higher in patients with acute thrombotic thrombocytopenic purpura - indicating a role of innate immunity in acute autoimmune TTP (show ADAMTS13 Antibodies).

  8. CFH (show CFH Antibodies), ARMS2 (show ARMS2 Antibodies), and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .

  9. Neutralization of the complement factor C3-dependent antichlamydial activity was dependent on the proteolytic activity of Chlamydia trachomatis CPAF and correlated with the CPAF-mediated degradation of complement factor C3 and factor B (show ATP5S Antibodies).

  10. Elevated C3a is able to predict the mortality following cardiac resynchronization therapy of heart failure

Cow (Bovine) Complement Component 3 (C3) interaction partners

Xenopus laevis Complement Component 3 (C3) interaction partners

  1. Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR (show C3AR1 Antibodies), revealing an unexpected role of complement proteins in early vertebrate development.

C3 Antigen Profile

Antigen Summary

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

Alternative names and synonyms associated with C3

  • complement component c3a (c3a) antibody
  • complement component 3 (C3) antibody
  • complement component 3 (c3) antibody
  • complement C3-like (LOC100060539) antibody
  • complement component C3 (c3-1) antibody
  • endogenous retrovirus group K, member 13 (ERVK-13) antibody
  • AHUS5 antibody
  • AI255234 antibody
  • ARMD9 antibody
  • ASP antibody
  • c3 antibody
  • C3-1 antibody
  • C3a antibody
  • C3b antibody
  • C3d antibody
  • c3_D antibody
  • CPAMD1 antibody
  • HSE-MSF antibody
  • Plp antibody
  • sb:cb26 antibody
  • si:dkey-76b14.4 antibody
  • wu:fi34b03 antibody
  • wu:fj86e11 antibody

Protein level used designations for C3

cb26 , complement component 3 , acylation stimulating protein , complement C3 , complement component 3d , complement factor 3 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 , C3a anaphylatoxin , acylation-stimulating protein cleavage product , complement component C3 , complement component C3a , complement component C3b , prepro-C3 , complement C3 alpha chain , complement component C3d

321046 Danio rerio
455644 Pan troglodytes
703613 Macaca mulatta
100216255 Xenopus (Silurana) tropicalis
100060539 Equus caballus
12266 Mus musculus
100135462 Cavia porcellus
718 Homo sapiens
24232 Rattus norvegicus
397072 Sus scrofa
280677 Bos taurus
100009121 Oryctolagus cuniculus
476728 Canis lupus familiaris
396370 Gallus gallus
443475 Ovis aries
398666 Xenopus laevis
100136951 Oncorhynchus mykiss
100861467 Homo sapiens
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