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Browse our Complement 4 Proteins (C4)

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Complement 4 Proteins (C4)
On are 9 Complement 4 (C4) Proteins from 6 different suppliers available. Additionally we are shipping Complement 4 Antibodies (77) and Complement 4 Kits (49) and many more products for this protein. A total of 135 Complement 4 products are currently listed.
C4, C4-1, C4-2, C4b, C4B1, C4B2, C4B3, C4B5, C4B12, C4BD, C4B_2, C4F, CH, CO4, CPAMD3
list all proteins Gene Name GeneID UniProt
C4 24233 P08649
C4 721 P0C0L4 , P0C0L5

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Complement 4 Proteins (C4) by Origin

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Top referenced Complement 4 Proteins

  1. Human Complement 4 Protein expressed in Human - ABIN1880329 : Rosenfeld, Ruddy, Austen: Structural polymorphism of the fourth component of human complement. in The Journal of clinical investigation 1970 (PubMed)
    Show all 3 references for ABIN1880329

More Proteins for Complement 4 Interaction Partners

Cow (Bovine) Complement 4 (C4) interaction partners

  1. The C4A (show C4B Proteins)-complete transcript is the main transcript under normal physiological conditions, while C4A (show C4B Proteins)-AS is augmented when mastitis develops.

Human Complement 4 (C4) interaction partners

  1. C4A (show C4B Proteins) and C4B (show C4B Proteins) gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus

  2. Data indicate Ig-like transcript 4 (ILT4 (show LILRB2 Proteins)) as a cellular receptor for complement split products (CSPs) complement component 4d (C4d).

  3. Suggest a prominent prognostic value of C4d staining as a rejection marker in ABO compatible kidney transplantation.

  4. The interaction between C4BP (show C4BPA Proteins) and Leptospira interrogans LcpA, LigA and LigB is sensitive to ionic strength and inhibited by heparin.

  5. Schizophrenia risk from complex variation of complement component 4

  6. There was a significant association between C4d deposition on allograft endothelial cells and presence of class II DSA I chronic liver allograft failure.

  7. Carrying no copies of C4B (show C4B Proteins) significantly increases the risk of cCSC, whereas carrying three C4B (show C4B Proteins) copies is protective.

  8. our study indicates that Finnish NTM (show NTM Proteins) patients had significantly more often C4 deficiencies than the healthy control subjects.

  9. Serum C4b (show C4B Proteins), FN, and PEPD (show PEPD Proteins) are associated with the pathological changes of pulmonary tuberculosis.

  10. Complement activation products C3d (show C3 Proteins) and C4d binding to lymphocytes can reflect the disease activity of systemic lupus erythematosus and can be used as biomarkers for SLE.

Complement 4 (C4) Protein Profile

Protein Summary

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

Alternative names and synonyms associated with Complement 4 (C4)

  • complement 4 (C4)
  • complement component 4A (C4A)
  • complement component 4A (Rodgers blood group) (C4a)
  • complement component 4B (Chido blood group) (C4B)
  • C4 protein
  • C4-1 protein
  • C4-2 protein
  • C4b protein
  • C4B1 protein
  • C4B2 protein
  • C4B3 protein
  • C4B5 protein
  • C4B12 protein
  • C4BD protein
  • C4B_2 protein
  • C4F protein
  • CH protein
  • CO4 protein
  • CPAMD3 protein

Protein level used designations for Complement 4 Proteins (C4)

MHC-linked complement C4 , complement C4 , complement component 4 (within H-2S) , complement component 4, gene 1 , complement component 4B (Chido blood group) , complement component 4B (Childo blood group) , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 , Chido form of C4 , basic complement C4 , complement C4-B , complement C4B1a

426611 Gallus gallus
280678 Bos taurus
24233 Rattus norvegicus
721 Homo sapiens
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