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COMP Proteins

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
COMP Protein (C-Term) COMP Protein (C-Term) COMP Protein (C-Term) (ABIN1047991)

COMP Origin: Rat Recombinant > 95 % (SDS-PAGE)

COMP Protein (AA 21-757) (His tag) COMP Protein (AA 21-757) (His tag) COMP Protein (AA 21-757) (His tag) (ABIN3091894)

Crystallography grade COMP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

COMP Protein (AA 20-755) (His tag) COMP Protein (AA 20-755) (His tag) COMP Protein (AA 20-755) (His tag) (ABIN3137424)

Crystallography grade COMP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

COMP Proteins by Grade

Find COMP Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Origin

Find COMP Proteins for a variety of species such as anti-Human COMP, anti-Rat COMP, anti-Mouse COMP. The species listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Source

Here you will find COMP Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

COMP Proteins by Protein Type

Here you can find COMP Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

COMP Proteins by Application

Find COMP Proteins validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

COMP Proteins by Biological Activity

Find COMP Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular COMP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source
Validations
  • (1)
  • (1)
Cat. No. ABIN1047991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091894
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137424
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505321
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7534406
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393391
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421479
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393394
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402583
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402586
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393397
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403273
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
Cat. No. ABIN7508516
Quantity 500 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2180897
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our COMP Proteins

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP Proteins

cartilage oligomeric matrix protein (COMP) Proteins
cartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins
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