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COMP Proteins

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
Cartilage Oligomeric Matrix Protein (COMP) (C-Term) protein Cartilage Oligomeric Matrix Protein (COMP) (C-Term) protein Cartilage Oligomeric Matrix Protein (COMP) (C-Term) protein (ABIN1047991)

COMP Origin: Rat Recombinant > 95 % (SDS-PAGE)

Cartilage Oligomeric Matrix Protein (COMP) (AA 21-757) protein (His tag) Cartilage Oligomeric Matrix Protein (COMP) (AA 21-757) protein (His tag) Cartilage Oligomeric Matrix Protein (COMP) (AA 21-757) protein (His tag) (ABIN3091894)

Crystallography grade COMP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Cartilage Oligomeric Matrix Protein (COMP) (AA 20-755) protein (His tag) Cartilage Oligomeric Matrix Protein (COMP) (AA 20-755) protein (His tag) Cartilage Oligomeric Matrix Protein (COMP) (AA 20-755) protein (His tag) (ABIN3137424)

Crystallography grade COMP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

COMP Proteins by Grade

Find COMP Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Origin

Find COMP Proteins for a variety of species such as anti-Human COMP, anti-Rat COMP, anti-Mouse COMP. The species listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Source

Find COMP Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Protein Type

Find COMP Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Application

Find COMP Proteins validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular COMP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2180897
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712452
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079504
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079508
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079506
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079509
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079510
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079505
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7079507
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN1061972
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474230
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our COMP Proteins

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP Proteins

cartilage oligomeric matrix protein (COMP) Proteins
cartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins
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