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Human Kallikrein 11 Protein expressed in Human Cells - ABIN2003367
Yousef, Scorilas, Diamandis: Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family. in Genomics 2000
Show all 5 references for ABIN2003367
Mouse (Murine) Kallikrein 11 Protein expressed in Human Cells - ABIN2008408
Gan, Lee, Smith, Argonza-Barrett, Lei, McCuaig, Moss, Paeper, Wang: Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. in Gene 2000
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Human Kallikrein 11 Protein expressed in HEK-293 Cells - ABIN2181429
Mitsui, Yamada, Okui, Kominami, Uemura, Yamaguchi: A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate. in Biochemical and biophysical research communications 2000
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KLK11 mRNA expression could be considered as a new molecular prognostic biomarker in colorectal adenocarcinoma
hK11 expression in gastric cancer appears to be associated with a better prognosis. hK11 may be a prognostic biomarker of gastric cancer.
The aim of this study was to monitor serum levels of two microRNAs (miR-21 and miR-141) and three kallikreins (hK3/PSA, hK11, and hK13) before and 1, 5, and 30 days after radical prostatectomy.
Our data showed that UVB-induced TSLP (show TSLP Proteins) might increase secretion of the T-helper type 2-attracting chemokine (c-c motif) ligand 17 (show CCL17 Proteins) by human dendritic cells.
HOXB8 (show HOXB8 Proteins) and KLK11 may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients
Human airway trypsin-like protease (show TMPRSS11D Proteins) can stimulate mucin5AC hypersecretion through a PAR2 (show F2RL1 Proteins)-mediated signaling pathway in 16HBE cells.
Patients harboring KLK11-positive tumors had a significantly decreased risk of death.
Low KLK11 protein expression is associated with gastric cancer.
For the first time, we report lower expression of KLK11 in CaP compared to BPH (show GLI3 Proteins) and slight upregulation of KLK11 in advanced tumors compared to localized ones
the up-regulation of TMPRSS2 (show TMPRSS2 Proteins) and the down-regulation of KLK11 in advanced and more aggressive tumors may open the feasibility of being used as biomarkers distinguishing the tumor aggressiveness as well as novel prognostic indicators for prostate cancer.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
kallikrein-related peptidase 11
, kallikrein 11
, protease, serine, 20
, serine protease 20
, trypsin-like protease