Kallikrein 11 Protein (KLK11) (AA 19-250) (His tag)
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- Target See all Kallikrein 11 (KLK11) Proteins
- Kallikrein 11 (KLK11)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-250
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Kallikrein 11 protein is labelled with His tag.
- Purpose
- Recombinant Human Kallikrein 11/KLK11 (C-6His)
- Sequence
- ETRIIKGFEC KPHSQPWQAA LFEKTRLLCG ATLIAPRWLL TAAHCLKPRY IVHLGQHNLQ KEEGCEQTRT ATESFPHPGF NNSLPNKDHR NDIMLVKMAS PVSITWAVRP LTLSSRCVTA GTSCLISGWG STSSPQLRLP HTLRCANITI IEHQKCENAY PGNITDTMVC ASVQEGGKDS CQGDSGGPLV CNQSLQGIIS WGQDPCAITR KPGVYTKVCK YVDWIQETMK NNVDHHHHHH
- Characteristics
- Recombinant Human Kallikrein 11 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu19-Asn250) of Human KLK11 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product KLK11 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Kallikrein 11 (KLK11)
- Alternative Name
- kallikrein-11 (KLK11 Products)
- Synonyms
- KLK11 Protein, 2310015I08Rik Protein, Prss20 Protein, TLSP Protein, PRSS20 Protein, kallikrein related peptidase 11 Protein, kallikrein related-peptidase 11 Protein, kallikrein-related peptidase 11 Protein, KLK11 Protein, Klk11 Protein
- Sub Type
- Fusionprotein
- Background
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Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
Alternative Names: Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP - Molecular Weight
- 26.28 kDa
- UniProt
- Q9UBX7
- Pathways
- Complement System
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