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Browse our anti-BARD1 (BARD1) Antibodies

Full name:
anti-BRCA1 Associated RING Domain 1 Antibodies (BARD1)
On www.antibodies-online.com are 81 BRCA1 Associated RING Domain 1 (BARD1) Antibodies from 18 different suppliers available. Additionally we are shipping BARD1 Kits (4) and BARD1 Proteins (4) and many more products for this protein. A total of 92 BARD1 products are currently listed.
Synonyms:
BARD1, ENSMUSG00000060893, ENSMUSG00000073653, LOC100147913
list all antibodies Gene Name GeneID UniProt
BARD1 580 Q99728
BARD1 12021 O70445
BARD1 64557 Q9QZH2

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anti-Human BARD1 Antibodies:

anti-Mouse (Murine) BARD1 Antibodies:

anti-Rat (Rattus) BARD1 Antibodies:

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Top referenced anti-BARD1 Antibodies

  1. Human Monoclonal BARD1 Primary Antibody for ELISA - ABIN395260 : Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010 (PubMed)
    Show all 5 references for ABIN395260

  2. Human Polyclonal BARD1 Primary Antibody for EIA, WB - ABIN950603 : Dizin, Irminger-Finger: Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1. in The international journal of biochemistry & cell biology 2010 (PubMed)
    Show all 3 references for ABIN950603

  3. Human Polyclonal BARD1 Primary Antibody for WB - ABIN654621 : Irminger-Finger: BARD1, a possible biomarker for breast and ovarian cancer. in Gynecologic oncology 2010 (PubMed)

  4. Human Polyclonal BARD1 Primary Antibody for IF (p), IHC (p) - ABIN706496 : Liu, Ao, Jia, Bai, Xu, Hu, Jiang, Chen, Wu: FOXK2 transcription factor suppresses ER?-positive breast cancer cell growth through down-regulating the stability of ER? via mechanism involving BRCA1/BARD1. in Scientific reports 2015 (PubMed)

  5. Human Polyclonal BARD1 Primary Antibody for ELISA, WB - ABIN1534425 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

More Antibodies against BARD1 Interaction Partners

Human BRCA1 Associated RING Domain 1 (BARD1) interaction partners

  1. Study presents four different pathogenic BARD1 variants identified in ovarian cancer patients. Three of them result in incorrect splicing of the corresponding exons, which may prompt expression of specific BARD1 isoforms and carcinogenesis.

  2. Suggest BARD1 as a driver of proliferation and of pulmonary fibrosis pathogenesis.

  3. a role for the BRCT domain in stimulating BARD1 nuclear export and mitochondrial localization, and in assembling mitochondrial BARD1/p53 (show TP53 Antibodies) complexes to regulate specific activities such as apoptotic function.

  4. Mutations do not contribute substantially (>> 10% of the total BARD1 mutations) to BARD1 sequence variation and, subsequently, to familial breast and/or ovarian cancer aggregation.

  5. BARD1 interacts with H3K9me2 through HP1 (show DEFA1 Antibodies) and plays a critical role in retention of a BRCA1/BARD1 complex at the site of DNA damage.

  6. FOXK2 (show FOXK2 Antibodies) might act as a negative regulator of ERalpha (show ESR1 Antibodies), and its association with both ERalpha (show ESR1 Antibodies) and BRCA1/BARD1 could lead to the down-regulation of ERalpha (show ESR1 Antibodies) transcriptional activity, effectively regulating the function of ERalpha (show ESR1 Antibodies).

  7. Increased expression of the BARD1 protein, with its ubiquitin ligase function, was associated with significantly improved overall and disease-free survival, which has yet to be documented for ACC.

  8. BARD1 long non-coding RNA is overexpressed in neoplasms.

  9. HDACi (histone deacetylase (show HDAC1 Antibodies) inhibitor) Vorinostat reduces BARD1 mRNA levels by increasing miR (show MLXIP Antibodies)-19a and miR (show MLXIP Antibodies)-19b expression levels.

  10. BARD1 is frequently overexpressed in brain metastases from breast cancer and may constitute a mechanism to overcome reactive oxygen species-mediated genotoxic stress in the metastatic brain.

Mouse (Murine) BRCA1 Associated RING Domain 1 (BARD1) interaction partners

  1. Suggest BARD1 as a driver of proliferation and of pulmonary fibrosis pathogenesis.

  2. identification of BARD1 as mediator between proapoptotic stress and p53 (show TP53 Antibodies)-dependent apoptosis

  3. the developmental functions of Brca1 (show BRCA1 Antibodies) and Bard1 are mediated by the Brca1 (show BRCA1 Antibodies)/Bard1 heterodimer.

  4. Data show that expression of truncated mouse or human BARD1 peptides capable of interacting with Brca1 results in a homologous-repair deficiency.

  5. the ankyrin and BRCT motifs of BARD1 are each essential for both chromosome stability and homology-directed DNA repair.

  6. The remarkable similarities between the mammary carcinomas of Bard1-, Brca1 (show BRCA1 Antibodies)-, and Bard1/Brca1 (show BRCA1 Antibodies)-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1 (show BRCA1 Antibodies)/BARD1 heterodimer.

BARD1 Antigen Profile

Antigen Summary

This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer.

Alternative names and synonyms associated with BARD1

  • BRCA1 associated RING domain 1 (BARD1) antibody
  • novel protein similar to vertebrate BRCA1 associated RING domain 1 (BARD1) (CH211-207D8.3) antibody
  • BRCA1 associated RING domain 1 (LOC100229796) antibody
  • BRCA1 associated RING domain 1 (bard1) antibody
  • BRCA1 associated RING domain 1 (Bard1) antibody
  • BARD1 antibody
  • ENSMUSG00000060893 antibody
  • ENSMUSG00000073653 antibody
  • LOC100147913 antibody

Protein level used designations for BARD1

BRCA1 associated RING domain 1 , BRCA1-associated RING domain protein 1-like , BRCA1 associated RING domain 1 isoform alfa , BRCA1 associated RING domain 1 isoform beta , BRCA1 associated RING domain 1 isoform delta , BRCA1 associated RING domain 1 isoform epsilon , BRCA1 associated RING domain 1 isoform eta , BRCA1 associated RING domain 1 isoform gamma , BRCA1 associated RING domain 1 isoform phi , BRCA1-associated RING domain gene 1 , BRCA1-associated RING domain protein 1 , BARD-1

GENE ID SPECIES
100053962 Equus caballus
470638 Pan troglodytes
694301 Macaca mulatta
100147913 Danio rerio
100229796 Taeniopygia guttata
100405252 Callithrix jacchus
100447274 Pongo abelii
100471907 Ailuropoda melanoleuca
100538376 Meleagris gallopavo
100563125 Anolis carolinensis
100600973 Nomascus leucogenys
580 Homo sapiens
424010 Gallus gallus
610190 Canis lupus familiaris
100156005 Sus scrofa
530961 Bos taurus
12021 Mus musculus
64557 Rattus norvegicus
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