Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human CETN2 Protein expressed in Escherichia coli (E. coli) - ABIN667312
Araki, Masutani, Takemura, Uchida, Sugasawa, Kondoh, Ohkuma, Hanaoka: Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair. in The Journal of biological chemistry 2001
Show all 2 references for ABIN667312
This study demonistrated that CETN2 regulates protein trafficking of olfactory cilia and participates in specifying planar polarity of ependymal cilia.
Binding of Cen2 and Cen4 to Gbetagamma of non-visual G-proteins regulates G-proteins involved in centrosome and basal body functions
Cetn3 (show CETN3 Proteins) inhibits Mps1 (show IDUA Proteins) autophosphorylation at Thr (show TRH Proteins)-676, a known site of T-loop autoactivation, and interferes with Mps1 (show IDUA Proteins)-dependent phosphorylation of Cetn2. The cellular overexpression of Cetn3 (show CETN3 Proteins) attenuates the incorporation of Cetn2 into centrioles and centrosome reduplication, whereas depletion of Cetn3 (show CETN3 Proteins) generates extra centrioles.
Centrin2 regulates primary ciliogenesis through controlling CP110 levels.
co-depletion of centrin 2 and PCID2 (show PCID2 Proteins) leads to blocking rather than delaying nuclear protein (show RDBP Proteins) export, indicating the dominance of the centrin 2 phenotype.
Data indicate that overexpression of the centrin (show CETN1 Proteins) interactor POC5 (show POC5 Proteins) leads to the assembly of linear, centrin (show CETN1 Proteins)-dependent structures.
CDC25B (show CDC25B Proteins), through activation of a centrosomal pool of CDK2 (show CDK2 Proteins), stabilises the local pool of Mps1 (show IDUA Proteins) which in turn regulates the level of centrin 2 at the centrosome.
Cen2 influences the binding of RPA (show RPA1 Proteins) and XPA (show XPA Proteins) with damaged DNA.
xeroderma pigmentosum complementation group C (show XPC Proteins) expression correlates with a decreased amount of CENTRIN 2 transcript and protein
The stability of centrin (show CETN1 Proteins) is regulated in part by Aurora A (show AURKA Proteins).
Mps1 (show IDUA Proteins)-dependent phosphorylation of Cetn2 stimulates the canonical centriole assembly pathway.
CDC25B (show CDC25B Proteins) forms a close association with Ctn (show CALCA Proteins)-2 proteins at the centrosome.
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.
, caltractin, 20 kDa calcium binding protein
, caltractin (20kD calcium-binding protein)