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Browse our MGMT (MGMT) ELISA Kits

Full name:
O6-Methylguanine-DNA-Methyltransferase ELISA Kits (MGMT)
On www.antibodies-online.com are 24 O6-Methylguanine-DNA-Methyltransferase (MGMT) ELISA Kits from 7 different suppliers available. Additionally we are shipping MGMT Antibodies (202) and MGMT Proteins (22) and many more products for this protein. A total of 260 MGMT products are currently listed.
Synonyms:
Agat, AGT, AI267024
list all ELISA KIts Gene Name GeneID UniProt
MGMT 4255  
MGMT 17314 P26187
MGMT 25332 P24528

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Show all synonyms

Top referenced MGMT ELISA Kits

  1. Human MGMT ELISA Kit for Sandwich ELISA - ABIN416869 : Safdar, Payne, Tu, Taite: Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity. in Biotechnology and bioengineering 2013 (PubMed)

More ELISA Kits for MGMT Interaction Partners

Human O6-Methylguanine-DNA-Methyltransferase (MGMT) interaction partners

  1. This study study identified clinicopathological factors related to postoperative seizure in high-grade gliomas and found two predictive biomarkers of postoperative seizure: MGMT and EGFR (show EGFR ELISA Kits)

  2. MGMT expression was identified as positive prognostic factor in patients with newly diagnosed glioblastoma who underwent surgical resection followed by adjuvant radiotherapy and concomitant oral TMZ chemotherapy.

  3. MGMT promoter methylationis associated with glioblastoma.

  4. The present study shows a tendency that HMGA 2 overexpression correlates with a poor prognosis of glioblastoma patients independent of MGMT methylation status. The results suggest that HMGA 2 could play an important role in the treatment of glioblastoma and could have a function in prognosis of this type of cancer.

  5. Study shows that MGMT DNA methylation (show HELLS ELISA Kits) status influences significantly on the prognosis of patients with glioblastoma.

  6. testing for DNA methylations of MGMT plus DAPK1 (show DAPK1 ELISA Kits) genes holds some promise for high grade cervical disease screening

  7. This review briefly describes the newer aspects of MGMT posttranslational regulation by ubiquitination, sumoylation and glutathionylation and reveals how the reactivity of the active site Cys145 can be exploited for potent inhibition and depletion of MGMT by thiol-reacting drugs such as the disulfiram and various dithiocarbamate derivatives. [review]

  8. Human O(6) -alkylguanine DNA alkyltransferase (hAGT) was capable of repairing both alkylene intrastrand cross-link containing duplexes with slightly greater efficiency towards the heptylene analog.

  9. MLH1 (show MLH1 ELISA Kits) and MGMT methylation correlated inversely when the tumor was located in the lower third of the stomach

  10. SFN (show SFN ELISA Kits) effectively inhibited activity of NF-kappaB (show NFKB1 ELISA Kits) signaling pathway and then reduced MGMT expression.

Mouse (Murine) O6-Methylguanine-DNA-Methyltransferase (MGMT) interaction partners

  1. This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG, as a key node in determining a carcinogenic threshold.

  2. Findings suggest that O6-methylguanine-DNA methyltransferase (MGMT)-mediated temozolomide resistance is associated with increased histone acetylation.

  3. Loss of MGMT expression and high Ezrin (show EZR ELISA Kits) protein expression leads to esophageal cancer.

  4. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.

  5. ta indicate that Zik1 and Gja9 demonstrated cancer-specific aberrant DNA methylation, whereas, Cdkn2a/p16, Igfbp3, Mgmt, Id4, and Cxcr4 were methylated in both the AOM tumors and normal colon mucosa.

  6. Roles of MGMT and MLH1 (show MLH1 ELISA Kits) proteins in alkylation-induced apoptosis and mutagenesis.

  7. Repression of MGMT is associated with precancerous conditions in hyperplastic mucosa adjacent to colon cancer

  8. GAMT (show GAMT ELISA Kits) and AGAT (show GATM ELISA Kits) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (show DMD ELISA Kits) muscle compared to C57

  9. MGMT-deficient cells would likely exhibit an increased mutational burden, but only following exposures to specific environmental mutagens such as the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

  10. Mgmt suppresses intestinal cancer associated with exogenous alkylating agents.

MGMT Antigen Profile

Antigen Summary

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

Alternative names and synonyms associated with MGMT

  • O-6-methylguanine-DNA methyltransferase (MGMT) Elisa Kit
  • O-6-methylguanine-DNA methyltransferase (Mgmt) Elisa Kit
  • Agat Elisa Kit
  • AGT Elisa Kit
  • AI267024 Elisa Kit

Protein level used designations for MGMT

6-O-methylguanine-DNA methyltransferase , O-6-methylguanine-DNA-alkyltransferase , O6-methylguanine-DNA methyltransferase , methylated-DNA--protein-cysteine methyltransferase , methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , 0-6-methylguanine-DNA methyltransferase , O(6)-alkylguanine-DNA alkyltransferase , O6-alkylguanine-DNA alkyltransferase , O6-methylguanine-DNA methyltranferase , O6-alkylguanine-DNA-alkyltransferase , O6-methylguanine-DNA-methyltransferase

GENE ID SPECIES
4255 Homo sapiens
17314 Mus musculus
25332 Rattus norvegicus
100733185 Cavia porcellus
100155050 Sus scrofa
616091 Bos taurus
442978 Canis lupus familiaris
423965 Gallus gallus
101106897 Ovis aries
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