MGMT Products
(O6-Methylguanine-DNA-Methyltransferase (MGMT))
Categories
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a
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Featured MGMT Categories
MGMT Antibodies
High quality antibodies with extensive validation data.
MGMT ELISA Kits
Reliable ELISA kits for a wide range of species.
MGMT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MGMT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (7)
Cat. No.
ABIN5542437
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN730768
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (4)
Cat. No.
ABIN7434551
Quantity
100 μL
Datasheet
Datasheet
Recommended MGMT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958286
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969037
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958287
Quantity
96 tests
Datasheet
Datasheet
Recommended MGMT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124248
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310882
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310884
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MGMT products
: "Effects of Some Growth Factors and Cytokines on the Expression of the Repair Enzyme MGMT and Protein MARP in Human Cells In Vitro : Effect of Some Growth Factors and Cytokines." in: Biochemical genetics, Vol. 56, Issue 5, pp. 459-477, (2018) (PubMed).: "PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas." in: Oncotarget, Vol. 8, Issue 9, pp. 15827-15837, (2017) (PubMed).
: "MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case." in: Journal of chemotherapy (Florence, Italy), Vol. 29, Issue 4, pp. 238-244, (2017) (PubMed).
: "Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line." in: Journal of the neurological sciences, Vol. 367, pp. 101-6, (2017) (PubMed).
: "IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. ..." in: Scientific reports, Vol. 6, pp. 27569, (2016) (PubMed).
: "Temozolomide promotes genomic and phenotypic changes in glioblastoma cells." in: Cancer cell international, Vol. 16, pp. 36, (2016) (PubMed).
: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." in: Japanese journal of clinical oncology, (2015) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).
: "Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 10, pp. 2727-39, (2014) (PubMed).
Synonyms and alternative names related to MGMT
O-6-methylguanine-DNA methyltransferase (MGMT), O-6-methylguanine-DNA methyltransferase (Mgmt), Agat, AGT, AI267024Protein level used designations for MGMT
- 6-O-methylguanine-DNA methyltransferase
- O-6-methylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA methyltransferase
- methylated-DNA--protein-cysteine methyltransferase
- methylguanine-DNA methyltransferase
- O-6-alkylguanine-DNA alkyltransferase
- 0-6-methylguanine-DNA methyltransferase
- O(6)-alkylguanine-DNA alkyltransferase
- O6-alkylguanine-DNA alkyltransferase
- O6-methylguanine-DNA methyltranferase
- O6-alkylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA-methyltransferase
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