You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our PALB2 Proteins (PALB2)

Full name:
Partner and Localizer of BRCA2 Proteins (PALB2)
On are 3 Partner and Localizer of BRCA2 (PALB2) Proteins from 2 different suppliers available. Additionally we are shipping PALB2 Antibodies (71) and PALB2 Kits (2) and many more products for this protein. A total of 82 PALB2 products are currently listed.
4732427B05, BC066140, FANCN, PALB2, PNCA3, RGD1304759, si:ch211-14k19.9
list all proteins Gene Name GeneID UniProt
PALB2 79728 Q86YC2
PALB2 233826 Q3U0P1
PALB2 293452  

Show all synonyms

PALB2 Proteins (PALB2) by Origin

Select your origin of interest

More Proteins for PALB2 Interaction Partners

Human Partner and Localizer of BRCA2 (PALB2) interaction partners

  1. Results identified novel intronic mutations in PALB2 gene associated with early-onset breast cancer patients from Turkey. PABL2 mutations accounted for 4.03 % in BRCA1/2-negative Turkish patients.

  2. rs120963 and rs249954 of the PALB2 gene are associated with increased breast cancer risk, and the association of rs249935 with breast cancer risk may be modified by the tumor pathological characteristics.

  3. PALB2 mutations are associated with susceptibility to Pancreatic ductal adenocarcinoma in the Czech Republic.

  4. PALB2 germline mutations are associated with breast and/or ovarian cancer.

  5. 87 out of 91 (95.6%) primary tumors were positive for PALB2 expression, as checked at the mRNA level.

  6. PALB2 mutations account for a small, but not negligible, proportion of patients with hereditary predisposition to breast cancer in the Xinjing region of China.

  7. a foundation for the formation and bioactivity of the G-quadruplex in the promoter region of PALB2 gene

  8. PALB2 mutations make a small contribution to the heritable breast cancer susceptibility in French population.

  9. Although patient cells were unable to form Rad51 (show RAD51 Proteins) foci following exposure to either DNA damaging agent, U2OS cells, in which the mutant PALB2 with in frame skip of exon 6 was induced, did show recruitment of Rad51 (show RAD51 Proteins) to foci following damage.

  10. The aim of this study was to determine the frequency and spectrum of germline mutations in BRCA1, BRCA2 and PALB2 and to evaluate the presence of the CHEK2 c.1100delC allele in these patients.

Mouse (Murine) Partner and Localizer of BRCA2 (PALB2) interaction partners

  1. results underscore the in vivo importance of the PALB2-BRCA1 complex formation in DSB repair and male meiosis

  2. Palb2 synergizes with Trp53 (show TP53 Proteins) to suppress mammary tumor formation in a model of inherited breast cancer.

  3. A key function for PALB2 is to interact with and to build up appropriate communication between BRCA1 (show BRCA1 Proteins) and BRCA2 (show BRCA2 Proteins).

PALB2 Protein Profile

Protein Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.

Alternative names and synonyms associated with PALB2

  • partner and localizer of BRCA2 (PALB2)
  • partner and localizer of BRCA2 (palb2)
  • partner and localizer of BRCA2 (LOC100356031)
  • partner and localizer of BRCA2 (Palb2)
  • 4732427B05 protein
  • BC066140 protein
  • FANCN protein
  • PALB2 protein
  • PNCA3 protein
  • RGD1304759 protein
  • si:ch211-14k19.9 protein

Protein level used designations for PALB2

partner and localizer of BRCA2 , Fanconi N , Fanconi anemia , complementation group N , partner and localizer of BRCA2-like

416572 Gallus gallus
453988 Pan troglodytes
558923 Danio rerio
608527 Canis lupus familiaris
700843 Macaca mulatta
733293 Xenopus laevis
100069097 Equus caballus
100356031 Oryctolagus cuniculus
100408318 Callithrix jacchus
100436331 Pongo abelii
100479015 Ailuropoda melanoleuca
100523630 Sus scrofa
100593417 Nomascus leucogenys
79728 Homo sapiens
233826 Mus musculus
293452 Rattus norvegicus
507620 Bos taurus
Selected quality suppliers for PALB2 Proteins (PALB2)
Did you look for something else?