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PALB2 Products

(Partner and Localizer of BRCA2 (PALB2))

Categories

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008].

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Featured PALB2 Categories

PALB2 Antibodies

High quality antibodies with extensive validation data.

PALB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PALB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Pig
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (1)
Cat. No. ABIN670536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN655634
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6748465
Quantity 100 μL
Datasheet Datasheet

Recommended PALB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1147067
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1147068
Quantity 96 tests
Datasheet Datasheet

Recommended PALB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094346
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3135003
Quantity 1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750731
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our PALB2 products

Li, Stokes, Chater, Roy, de Bruin, Hu, Liu, Smit, Heynen, Downward, Seckl, Wang, Tang, Pardo: "Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer." in: Cell discovery, Vol. 2, pp. 16031, (2016) (PubMed).

Loke, Pearlman, Upadhyay, Tesfa, Shao, Ostrer: "Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway." in: Human molecular genetics, Vol. 24, Issue 11, pp. 3030-7, (2016) (PubMed).

Brough, Bajrami, Vatcheva, Natrajan, Reis-Filho, Lord, Ashworth: "APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer." in: The EMBO journal, Vol. 31, Issue 5, pp. 1160-76, (2012) (PubMed).

Martrat, Maxwell, Tominaga, Porta-de-la-Riva, Bonifaci, Gómez-Baldó, Bogliolo, Lázaro, Blanco, Brunet, Aguilar, Fernández-Rodríguez, Seal, Renwick, Rahman, Kühl, Neveling, Schindler, Ramírez et al.: "Exploring the link between MORF4L1 and risk of breast cancer. ..." in: Breast cancer research : BCR, Vol. 13, Issue 2, pp. R40, (2011) (PubMed).

Zhang, Fan, Ren, Andreassen: "PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2." in: Molecular cancer research : MCR, Vol. 7, Issue 7, pp. 1110-8, (2009) (PubMed).

Synonyms and alternative names related to PALB2

partner and localizer of BRCA2 (PALB2), partner and localizer of BRCA2 (palb2), partner and localizer of BRCA2 L homeolog (palb2.L), partner and localizer of BRCA2 (Palb2), 4732427B05, BC066140, Fancn, FANCN, PALB2, PNCA3, RGD1304759, si:ch211-14k19.9

Protein level used designations for PALB2

  • partner and localizer of BRCA2
  • Fanconi N
  • Fanconi anemia
  • complementation group N
  • partner and localizer of BRCA2-like
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