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Browse our PRKDC (PRKDC) ELISA Kits

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Protein Kinase, DNA-Activated, Catalytic Polypeptide ELISA Kits (PRKDC)
On are 9 Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) ELISA Kits from 5 different suppliers available. Additionally we are shipping PRKDC Antibodies (407) and PRKDC Proteins (8) and many more products for this protein. A total of 432 PRKDC products are currently listed.
AI326420, AU019811, DNA-PKCS, DNAPDcs, dnapk, dnpk1, DOXNPH, dxnph, hyrc, hyrc1, p350, p460, PRKDC, prkdc-A, scid, slip, xrcc7
list all ELISA KIts Gene Name GeneID UniProt
PRKDC 19090 P97313
PRKDC 5591 P78527

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More ELISA Kits for PRKDC Interaction Partners

Mouse (Murine) Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) interaction partners

  1. AIM2 (show AIM2 ELISA Kits) reduced Akt (show AKT1 ELISA Kits) activation and tumor burden in colorectal cancer models, while an Akt (show AKT1 ELISA Kits) inhibitor reduced tumor load in Aim2 (show AIM2 ELISA Kits)(-/-) mice

  2. PRKDC proteins that mediate non-homologous end joining have been identified as TRIP13 (show TRIP13 ELISA Kits) binding partners in head and neck cancer.

  3. NR5A1 (show NR5A1 ELISA Kits) prevents centriole splitting by inhibiting centrosomal DNA-PK activation and beta-catenin (show CTNNB1 ELISA Kits) accumulation

  4. Results show that DNA-PKcs functions as a selective modulator of transcriptional networks that induce cell migration, invasion, and metastasis of prostate cancer cells.

  5. These experiments define a novel requirement for 53BP1 (show TP53BP1 ELISA Kits) in the fusions of DNA-PKcs-deficient telomeres throughout the cell cycle.

  6. data suggest that DNA-PKcs-SIN1 (show MAPKAP1 ELISA Kits) complexation-mediated Akt (show AKT1 ELISA Kits) activation (Ser (show SIGLEC1 ELISA Kits)-473 phosphorylation) is required for mouse osteoblast differentiation

  7. Activated platelets accumulate in the brain rescue apoptotic neuron cells via activation of EGFR and DNA-dependent protein kinase.

  8. DNA-PK and ATM (show ATM ELISA Kits) acts in parallel upstream of XRCC4 (show XRCC4 ELISA Kits), regulating through phosphorylation

  9. DNA-PKcs is the molecular switch that coordinates end-processing and end-ligation at the DNAends through differential phosphorylations.

  10. DNA-PK/Chk2 (show CHEK2 ELISA Kits) signaling induces centrosome amplification upon long-term HU treatment, therefore increasing our insight into tumor recurrence after initial chemotherapy.

Human Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) interaction partners

  1. Together, our results provide evidence that acetylation potentially regulates DNA-PKcs.

  2. Inhibiting PRKDC radiosensitizes human osteosarcoma cells.

  3. these results suggest that miR (show MLXIP ELISA Kits)-101 sensitizes pancreatic cancer cells to gemcitabine possibly via downregulating DNA-PKcs.

  4. The bocavirus large viral nonstructural protein NS1 (show PTPN11 ELISA Kits) is sufficient to induce the DNA damage response and the activation of the host ATM (show ATM ELISA Kits), ATR (show ANTXR1 ELISA Kits), and DNAPK.

  5. inhibition of DNAPKcs decreases Pgp expression and sensitizes osteosarcoma cancer stem cells to chemotherapeutic agents in vitro

  6. These results suggested potential usefulness of the phosphorylation status of XRCC4 (show XRCC4 ELISA Kits) Ser320 as an indicator of DNA-PK functionality in living cells.

  7. Data show that elevated expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs), Akt3 (show AKT3 ELISA Kits) protein, and tumor suppressor protein p53 (p53 (show TP53 ELISA Kits)) in ovarian serous adenocarcinoma tissues are an indication of more advanced disease and worse prognosis.

  8. CDK2 (show CDK2 ELISA Kits) and DNA-PK regulate PR transcriptional activity by distinct mechanisms.

  9. Results show that under hypoxia, Ku70 (show XRCC6 ELISA Kits) and DNA-PKcs interact with nuclear RON (show MST1R ELISA Kits) which activates non-homologous end joining DNA repair conferring chemoresistance.

  10. A significantly different distribution was found in the frequency of PRKDC (rs7003908) genotype between the ESCC group and controls. Individuals homozygous for the C allele had a significant (3.185-fold) increased risk of ESCC.

Xenopus laevis Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) interaction partners

  1. Ku80 (show XRCC5 ELISA Kits) is susceptible to proteolytic degradation when not dimerized with Ku70 (show XRCC6 ELISA Kits); dimer induces DNA-PK activity; evidence that interacting domain(s) of Xenopus DNA-PKcs is conserved so as to interact with human Ku, reconstituting a functional holoenzyme

PRKDC Antigen Profile

Antigen Summary

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.

Alternative names and synonyms associated with PRKDC

  • protein kinase, DNA-activated, catalytic polypeptide (PRKDC) Elisa Kit
  • protein kinase, DNA activated, catalytic polypeptide (Prkdc) Elisa Kit
  • protein kinase, DNA-activated, catalytic polypeptide (prkdc) Elisa Kit
  • AI326420 Elisa Kit
  • AU019811 Elisa Kit
  • DNA-PKCS Elisa Kit
  • DNAPDcs Elisa Kit
  • dnapk Elisa Kit
  • dnpk1 Elisa Kit
  • DOXNPH Elisa Kit
  • dxnph Elisa Kit
  • hyrc Elisa Kit
  • hyrc1 Elisa Kit
  • p350 Elisa Kit
  • p460 Elisa Kit
  • PRKDC Elisa Kit
  • prkdc-A Elisa Kit
  • scid Elisa Kit
  • slip Elisa Kit
  • xrcc7 Elisa Kit

Protein level used designations for PRKDC

protein kinase, DNA-activated, catalytic polypeptide , protein kinase catalytic subunit (DNA-dependent protein kinase) , DNA-dependent protein kinase catalytic subunit , DNA-activated protein kinase catalytic polypeptide , DNA-dependent protein kinase catalytic subunit-like , DNA-PK catalytic subunit , doxorubicin nephropathy , severe combined immunodeficiency , hyper-radiosensitivity of murine scid mutation, complementing 1 , p460 , DNA-PKcs

282003 Bos taurus
418814 Gallus gallus
464165 Pan troglodytes
512740 Bos taurus
100125348 Oryctolagus cuniculus
100224961 Taeniopygia guttata
100399020 Callithrix jacchus
100586225 Nomascus leucogenys
100633457 Amphimedon queenslandica
19090 Mus musculus
5591 Homo sapiens
373602 Xenopus laevis
395376 Gallus gallus
474176 Canis lupus familiaris
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