Browse our RAD52 Proteins (RAD52)

Full name:
RAD52 Homolog (S. Cerevisiae) Proteins (RAD52)
On www.antibodies-online.com are 9 RAD52 Homolog (S. Cerevisiae) (RAD52) Proteins from 4 different suppliers available. Additionally we are shipping RAD52 Antibodies (107) and RAD52 Kits (5) and many more products for this protein. A total of 126 RAD52 products are currently listed.
Synonyms:
LOC100223085, MGC115453, RAD52, Rad52yh, zgc:112400
list all proteins Gene Name GeneID UniProt
RAD52 5893 P43351
RAD52 19365 P43352
Rat RAD52 RAD52 297561  

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RAD52 Proteins (RAD52) by Origin

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More Proteins for RAD52 Interaction Partners

Candida albicans RAD52 Homolog (S. Cerevisiae) (RAD52) interaction partners

  1. Rad51 (show RAD51 Proteins) and Rad52 physically interact with CENP-ACaCse4 in vivo.

  2. Rad52 prevents chromosome loss and truncation.

Human RAD52 Homolog (S. Cerevisiae) (RAD52) interaction partners

  1. Rad52 inverse strand exchange plays an important role in RNA-templated double strand break repair in vivo.

  2. The mitotic DNA synthesis is RAD52 dependent, and RAD52 is required for the timely recruitment of MUS81 (show MUS81 Proteins) and POLD3 (show POLD3 Proteins) to common fragile sites in early mitosis.

  3. Human RAD52-null cells retain a significant level of single-strand annealing (SSA (show TRIM21 Proteins)) activity demonstrating perforce that additional SSA (show TRIM21 Proteins)-like activities must exist in human cells. Moreover, the SSA (show TRIM21 Proteins) activity associated with RAD52 is involved in, but not absolutely required for, most homology-directed repair (HDR (show GATA3 Proteins)) subpathways. Specifically, a deficiency in RAD52 impaired the repair of DNA DSBs.

  4. Data suggest RAD52 binds tightly to RPA (show RPA1 Proteins)/ssDNA complex in presynaptic complex and inhibits RPA (show RPA1 Proteins) turnover; during presynaptic complex assembly, most of RPA (show RPA1 Proteins) and RAD52 is displaced from ssDNA, but some RAD52/RPA (show RPA1 Proteins)/ssDNA complexes persist as interspersed clusters surrounded by RAD51 (show RAD51 Proteins) filaments. (RAD52 = Rad52 DNA repair/recombination protein (show RAD50 Proteins); RPA (show RPA1 Proteins) = replication protein A (show GPR153 Proteins); ssDNA = single-stranded DNA; RAD51 (show RAD51 Proteins) = Rad51 (show RAD51 Proteins) recombinase (show RAG1 Proteins))

  5. The C-terminal region of yRad52, but not of hRAD52, is involved in ssDNA annealing. This suggests that the second DNA binding site is required for the efficient ssDNA annealing by yRad52. We propose an updated model of Rad52-mediated ssDNA annealing.

  6. Study discovered two cis (show CISH Proteins)-expression quantitative trait loci SNPs in the RAD52 gene that are associated with its expression and are also associated with lung squamous cell carcinomas (LUSC) risk.

  7. BRG1 (show SMARCA4 Proteins)-RAD52 complex mediates the replacement of RPA (show RPA1 Proteins) with RAD51 (show RAD51 Proteins) on single-stranded DNA (ssDNA) to initiate DNA strand invasion. Loss of BRG1 (show SMARCA4 Proteins) results in a failure of RAD51 (show RAD51 Proteins) loading onto ssDNA, abnormal homologous recombination repair

  8. these results implicate increased RAD52 expression in both genetic susceptibility and tumorigenesis of upper aerodigestive tract and lung squamous cell carcinoma tumors.

  9. RAD52 rs7963551 single nucleotide polymorphism was significantly associated with glioma risk.

  10. This study found that only the RAD52 rs7963551 single nucleotide polymorphism was significantly associated with hepatitis B virus related - hepatocellular carcinoma risk.

Mouse (Murine) RAD52 Homolog (S. Cerevisiae) (RAD52) interaction partners

  1. In cancer-prone, heterozygous APC (show APC Proteins) mutant mice, homozygous deletion of the Rad52 gene suppressed tumor growth and prolonged lifespan.

  2. Rad54 (show RAD54L Proteins) has a key function in maintaining genomic integrity of the developing germ cells.

  3. Loss of Rad52 partially rescues tumorigenesis and T-cell maturation in Atm (show ATM Proteins)-deficient mice.

  4. RAD52 modulates the outcome of recombinant HIV-l vector infection by markedly reducing the efficiency of productive integration events

  5. Inactivation of RAD52 aggravates X-ray and mitomycine C sensitivity in mice with RAD54 (show RAD54L Proteins) gene degect.

  6. Cells expressing Rad52 splice variants favor sister chromatid repair.

  7. Results indicate that RAD52 cooperates with OGG1 (show OGG1 Proteins) to repair oxidative DNA damage and enhances the cellular resistance to oxidative stress.

Pig (Porcine) RAD52 Homolog (S. Cerevisiae) (RAD52) interaction partners

  1. The complete cDNA sequences of the pig RAD51 (show RAD51 Proteins), RAD52, and RAD54 (show RAD54L Proteins) genes, which are closely related to homologous recombination events, arae identified using molecular cloning technique in pigs.

RAD52 Protein Profile

Protein Summary

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.

Alternative names and synonyms associated with RAD52

  • RAD52 homolog (S. cerevisiae) (RAD52)
  • RAD52 homolog (S. cerevisiae) (rad52)
  • RAD52 homolog (S. cerevisiae) (LOC100223085)
  • RAD52 homolog (rad52)
  • similar to S. cerevisiae RAD52 (YML032C) dsDNA break repair annealing factor (RAD52)
  • DNA repair and recombination protein, putative (RAD52)
  • RAD52 protein (rad52)
  • RAD52 homolog (S. cerevisiae) (Rad52)
  • LOC100223085 protein
  • MGC115453 protein
  • RAD52 protein
  • Rad52yh protein
  • zgc:112400 protein

Protein level used designations for RAD52

RAD52 homolog (S. cerevisiae) , DNA repair protein RAD52 homolog , DNA repair protein RAD52 homolog-like , RAD52 homolog , potential dsDNA break repair annealing factor , DNA repair and recombination protein, putative , RAD52 protein , recombination protein RAD52 , rhabdomyosarcoma antigen MU-RMS-40.23 , DNA repair protein RAD52 , RAD52 homolog isoform alpha

GENE ID SPECIES
466911 Pan troglodytes
554171 Danio rerio
100223085 Taeniopygia guttata
100403933 Callithrix jacchus
100426645 Macaca mulatta
100437058 Pongo abelii
100595332 Nomascus leucogenys
734642 Xenopus laevis
3647123 Candida albicans SC5314
3647148 Candida albicans SC5314
8048730 Candida dubliniensis CD36
10803753 Sordaria macrospora k-hell
100036666 Xenopus (Silurana) tropicalis
5893 Homo sapiens
418152 Gallus gallus
19365 Mus musculus
477729 Canis lupus familiaris
100141308 Sus scrofa
512897 Bos taurus
297561 Rattus norvegicus
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