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RAG2 Proteins

(Recombination Activating Gene 2 (RAG2))
This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008].
Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) (ABIN3094940)

Crystallography grade RAG2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) Recombination Activating Gene 2 (RAG2) (AA 1-527) protein (His tag) (ABIN3133308)

Crystallography grade RAG2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Recombination Activating Gene 2 (RAG2) protein (GST tag) Recombination Activating Gene 2 (RAG2) protein (GST tag) Recombination Activating Gene 2 (RAG2) protein (GST tag) (ABIN2752910)

RAG2 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

RAG2 Proteins by Grade

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RAG2 Proteins by Origin

Find RAG2 Proteins for a variety of species such as anti-Human RAG2, anti-Mouse RAG2. The species listed below are among those available. Click on a link to go to the corresponding products.

RAG2 Proteins by Source

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RAG2 Proteins by Protein Type

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RAG2 Proteins by Application

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Popular RAG2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN4369878
Quantity 2 μg
Datasheet Datasheet

Aliases for RAG2 Proteins

recombination activating 2 (RAG2) Proteins
recombination activating gene 2 (RAG2) Proteins
recombination activating gene 2 (Rag2) Proteins
recombination activating 2 (Rag2) Proteins
recombination activating gene 2 (rag2) Proteins
recombination activating gene 2 S homeolog (rag2.S) Proteins
RAG-2 Proteins
Rag-2 Proteins
rag-2 Proteins
zgc:136743 Proteins
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