Browse our RAD54L Proteins (RAD54L)

Full name:
RAD54-Like (S. Cerevisiae) Proteins (RAD54L)
On are 5 RAD54-Like (S. Cerevisiae) (RAD54L) Proteins from 3 different suppliers available. Additionally we are shipping RAD54L Antibodies (52) and many more products for this protein. A total of 60 RAD54L products are currently listed.
4833408C14Rik, AI447451, ATR2, DXHXS6677E, GdRAD54, hHR54, HP1-BP38, Hp1bp2, Hp1bp38, HR54, hRAD54, MGC69368, MRXS3, RAD54, RAD54-like, RAD54A, RAD54L, XH2, Xnp, zgc:56289, ZNF-HX
list all proteins Gene Name GeneID UniProt
RAD54L 22589 Q61687
Rat RAD54L RAD54L 298429  
RAD54L 8438 Q92698

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RAD54L Proteins (RAD54L) by Origin

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More Proteins for RAD54L Interaction Partners

Mouse (Murine) RAD54-Like (S. Cerevisiae) (RAD54L) interaction partners

  1. The long noncoding RNA, TERRA (show DMRT2 Proteins) can bind both in cis (show CISH Proteins) to telomeres and in trans to genic targets; a large network of interacting proteins was defined, including epigenetic factors, telomeric proteins, and the RNA helicase, ATRX (show ATRX Proteins). TERRA (show DMRT2 Proteins) and ATRX (show ATRX Proteins) share hundreds of target genes and are functionally antagonistic at these loci: whereas TERRA (show DMRT2 Proteins) activates, ATRX (show ATRX Proteins) represses gene expression.

  2. The changes of ATRX (show ATRX Proteins) distribution occur and partially correlate with the main stages of zygotic genome activation during mouse early development, butthese changes seem to be determined by other processes of structural and functional rearrangements of blastomere nuclei.

  3. ATRX (show ATRX Proteins) mutation is associated with increased mutation rate at the single-nucleotide variant (SNV) level.

  4. Daxx (show DAXX Proteins) and Atrx (show ATRX Proteins) safeguard the genome by silencing repetitive elements when DNA methylation (show HELLS Proteins) levels are low.

  5. A direct role of Atrx (show ATRX Proteins) in the establishment and robust maintenance of heterochromatin is demonstrated.

  6. We propose a model whereby ATRX-dependent deposition of H3.3 into heterochromatin is normally required to maintain the memory of silencing at imprinted loci.

  7. ATRX (show ATRX Proteins) promotes the incorporation of histone H3.3 (show H3F3A Proteins) at particular transcribed genes and facilitates transcriptional elongation through G-rich sequences.

  8. Using X chromosome inactivation as a model, study applied an unbiased proteomics approach to isolate Xist and PRC2 regulators and identified ATRX (show ATRX Proteins); ATRX (show ATRX Proteins) functions as a high-affinity RNA-binding protein that directly interacts with RepA/Xist RNA to promote loading of PRC2 in vivo. Without ATRX (show ATRX Proteins), PRC2 cannot load onto Xist RNA nor spread in cis (show CISH Proteins) along the X chromosome.

  9. These results indicate that while ATRX (show ATRX Proteins) plays limited roles during early stages of skeletal development, deficiency of the protein in adult tissues does not confer susceptibility to osteoarthritis.

  10. ATRX (show ATRX Proteins) plays a direct role in facilitating DNA replication. Ablation of ATRX (show ATRX Proteins) alone, although leading to a DNA damage response at telomeres, is not sufficient to trigger the alternative lengthening of telomere pathway in mouse embryonic stem cells.

Human RAD54-Like (S. Cerevisiae) (RAD54L) interaction partners

  1. Nap1 (show IL8 Proteins) binds to RAD54 (show ATRX Proteins).

  2. TAF12 (show TAF12 Proteins) and NFYC (show NFYC Proteins) are transcription factors that regulate the epigenome, whereas RAD54L (show ATRX Proteins) plays a central role in DNA repair

  3. support a model in which RAD54L (show ATRX Proteins) and RAD54B (show RAD54B Proteins) counteract genome-destabilizing effects of direct binding of RAD51 (show RAD51 Proteins) to dsDNA in tumor cells

  4. The RAD54L (show ATRX Proteins) polymorphism (2290C/T) can be used as a genetic marker inside the consensus deletion region at 1p32 in human meningiomas.

  5. Shortened telomeres in murine scid (show PRKDC Proteins) cells expressing mutant RAD54L (show ATRX Proteins) coincide wirth reduction in recombination at telomeres.

  6. hRad54, a Swi2/Snf2 (show SMARCA2 Proteins) protein, binds HJ-like structures with high specificity and promotes their bidirectional branch migration in an ATPase-dependent manner

  7. Some immortal cells use the alternative lengthening of telomeres (ALT) pathway to maintain their telomeres instead of telomerase. This is the first genetic evidence that Rad54 is dispensable for the ALT pathway.

  8. RAD54 (show ATRX Proteins) is recruited by RAD51 (show RAD51 Proteins)-ssDNA filament to the chromatin of the intact chromosome and it remodels that chromatin to facilitate accessibility for strand exchange

  9. analysis of human rad54 (show ATRX Proteins) protein interactions with branched DNA molecules

  10. Rad54 (show ATRX Proteins) protein causes dissociation of joint molecules by ATP-dependent branch-migration and therefore plays an important role in double strand DNA break repair.

Zebrafish RAD54-Like (S. Cerevisiae) (RAD54L) interaction partners

  1. Rad54 structure suggests that SWI2/SNF2 (show SMARCA4 Proteins) proteins use a mechanism analogous to helicases to translocate on dsDNA

RAD54L Protein Profile

Protein Summary

The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with RAD54L

  • RAD54-like (S. cerevisiae) (rad54l)
  • RAD54-like (S. cerevisiae) (RAD54L)
  • RAD54-like protein (RAD54L)
  • alpha thalassemia/mental retardation syndrome X-linked homolog (human) (Atrx)
  • RAD54 like (S. cerevisiae) (Rad54l)
  • 4833408C14Rik protein
  • AI447451 protein
  • ATR2 protein
  • DXHXS6677E protein
  • GdRAD54 protein
  • hHR54 protein
  • HP1-BP38 protein
  • Hp1bp2 protein
  • Hp1bp38 protein
  • HR54 protein
  • hRAD54 protein
  • MGC69368 protein
  • MRXS3 protein
  • RAD54 protein
  • RAD54-like protein
  • RAD54A protein
  • RAD54L protein
  • XH2 protein
  • Xnp protein
  • zgc:56289 protein
  • ZNF-HX protein

Protein level used designations for RAD54L

RAD54-like , RAD54-like protein , RAD54-like (S. cerevisiae) , ATP-dependent helicase ATRX , HP1 alpha-interacting protein , X-linked nuclear protein , alpha thalassemia/mental retardation syndrome (X-linked) , heterochromatin protein 2 , transcriptional regulator ATRX , DNA repair and recombination protein RAD54-like , RAD54 homolog , mHR54 , mRAD54 , putative recombination factor GdRad54

407922 Xenopus (Silurana) tropicalis
456563 Pan troglodytes
475368 Canis lupus familiaris
707740 Macaca mulatta
100414293 Callithrix jacchus
22589 Mus musculus
298429 Rattus norvegicus
19366 Mus musculus
8438 Homo sapiens
394119 Danio rerio
424611 Gallus gallus
100141305 Sus scrofa
100140639 Bos taurus
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