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Human FBLN3 Protein expressed in Wheat germ - ABIN1352379
Hu, Pioli, Siegel, Zhang, Nelson, Chaturbedi, Mathews, Ro, Alkafeef, Hsu, Hamamura, Yu, Hess, Tromberg, Linskey, Zhou: EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment. in Molecular cancer 2011
Show all 2 references for ABIN1352379
Human FBLN3 Protein expressed in HEK-293 Cells - ABIN2719970
Nandhu, Hu, Cole, Erdreich-Epstein, Rodriguez-Gil, Viapiano: Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas. in Cancer research 2014
Serum EFEMP1 is down-regulated and involved in the progression of Prostate Cancer. It may serve as a useful diagnostic biomarker, with better diagnostic accuracy than PSA (show PLAG1 Proteins) in Prostate Cancer.
SMRP (show ABCC5 Proteins) but not FBLN3 has a role in pleural effusions in in malignant pleural mesothelioma
EFEMP1 negatively modulates the migration ability in hepatocellular carcinoma. Reduction of EFEMP1 promotes the migration ability though increasing Matrix Metalloproteinase 2 (show MMP2 Proteins) and Matrix Metalloproteinase 9 (show MMP9 Proteins) expression via Extracellular Signal-Regulated MAP Kinase 1 (show MAPK3 Proteins)/2 activity.
The EFEMP1 rs3791679 polymorphism influences glioma susceptibility in the Chinese Han population.
Extensive methylation of the EFEMP1 gene promoter can discriminate invasive from benign IPMNs with superior accuracy owing to their stepwise accumulation of tumor progression
The results of our study suggested an association between the EFEMP1 rs3791679 polymorphism and an elevated risk of glioma, especially in those with family history of glioma.
Median FBLN-3 concentrations were 12.96.
The EFEMP1 gene is significantly down-regulated in leiomyoma compared with myometrium.
It was concluded that fibulin-3 is expressed at a lower level in colon cancer, and it can serve as a marker for advanced colon cancer.
Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1 (show WT1 Proteins), EBF2 (show EBF2 Proteins) and ADAMTS6 (show ADAMTS6 Proteins).
Define the Efemp1-p27(Kip1 (show CDKN1B Proteins)) axis as a potential marker module of PDAC cell sensitivity towards dual PI3K-mTOR (show FRAP1 Proteins) inhibitors.
The Efemp1 knock-in mice reconstitute the most important histopathologic symptoms of both Malattia leventinese and age-related macular degeneration.
fibulin-3 plays an important role in maintaining the integrity of fascia connective tissues and regulates aging.
both fibulin-3 and -5 are important in maintaining pelvic organ support in mice.
Data suggest a role for fibulin-3 in tissue maintenance and regeneration in the adult olfactory pathway.
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
EGF-containing fibulin-like extracellular matrix protein 1
, extracellular protein S1-5
, epidermal growth factor-containing fibulin-like extracellular matrix protein 1