Browse our Fibulin 3 Proteins (FBLN3)

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Fibulin 3 Proteins (FBLN3)
On are 14 Fibulin 3 (FBLN3) Proteins from 7 different suppliers available. Additionally we are shipping Fibulin 3 Antibodies (84) and Fibulin 3 Kits (20) and many more products for this protein. A total of 131 Fibulin 3 products are currently listed.
list all proteins Gene Name GeneID UniProt
FBLN3 2202 Q12805
FBLN3 305604  
FBLN3 216616 Q8BPB5

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Fibulin 3 Proteins (FBLN3) by Origin

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Top referenced Fibulin 3 Proteins

  1. Human FBLN3 Protein expressed in Wheat germ - ABIN1352379 : Hu, Pioli, Siegel, Zhang, Nelson, Chaturbedi, Mathews, Ro, Alkafeef, Hsu, Hamamura, Yu, Hess, Tromberg, Linskey, Zhou: EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment. in Molecular cancer 2011 (PubMed)
    Show all 2 references for 1352379

  2. Human FBLN3 Protein expressed in HEK-293 Cells - ABIN2719970 : Nandhu, Hu, Cole, Erdreich-Epstein, Rodriguez-Gil, Viapiano: Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas. in Cancer research 2014 (PubMed)

More Proteins for Fibulin 3 Interaction Partners

Human Fibulin 3 (FBLN3) interaction partners

  1. FBLN-3 promoter region was highly methylated in some pancreatic cancer cell lines. FBLN-3 inhibited c-MET activation and expression and reduced cellular level of ALDH1 (show ALDH1A1 Proteins).

  2. Serum EFEMP1 is down-regulated and involved in the progression of Prostate Cancer. It may serve as a useful diagnostic biomarker, with better diagnostic accuracy than PSA (show PLAG1 Proteins) in Prostate Cancer.

  3. SMRP (show ABCC5 Proteins) but not FBLN3 has a role in pleural effusions in in malignant pleural mesothelioma

  4. EFEMP1 negatively modulates the migration ability in hepatocellular carcinoma. Reduction of EFEMP1 promotes the migration ability though increasing Matrix Metalloproteinase 2 (show MMP2 Proteins) and Matrix Metalloproteinase 9 (show MMP9 Proteins) expression via Extracellular Signal-Regulated MAP Kinase 1 (show MAPK3 Proteins)/2 activity.

  5. The EFEMP1 rs3791679 polymorphism influences glioma susceptibility in the Chinese Han population.

  6. Extensive methylation of the EFEMP1 gene promoter can discriminate invasive from benign IPMNs with superior accuracy owing to their stepwise accumulation of tumor progression

  7. The results of our study suggested an association between the EFEMP1 rs3791679 polymorphism and an elevated risk of glioma, especially in those with family history of glioma.

  8. Median FBLN-3 concentrations were 12.96.

  9. The EFEMP1 gene is significantly down-regulated in leiomyoma compared with myometrium.

  10. It was concluded that fibulin-3 is expressed at a lower level in colon cancer, and it can serve as a marker for advanced colon cancer.

Mouse (Murine) Fibulin 3 (FBLN3) interaction partners

  1. Mutant fibulin-3 causes proteoglycan (show Vcan Proteins) accumulation, reduction of MMP-2 (show MMP2 Proteins) and MMP-9 (show MMP9 Proteins), but increase of TIMP-3 (show TIMP3 Proteins), and impairs diffusion across Bruch's membrane.

  2. Define the Efemp1-p27(Kip1 (show CDKN1B Proteins)) axis as a potential marker module of PDAC cell sensitivity towards dual PI3K-mTOR (show FRAP1 Proteins) inhibitors.

  3. The Efemp1 knock-in mice reconstitute the most important histopathologic symptoms of both Malattia leventinese and age-related macular degeneration.

  4. fibulin-3 plays an important role in maintaining the integrity of fascia connective tissues and regulates aging.

  5. both fibulin-3 and -5 are important in maintaining pelvic organ support in mice.

  6. Data suggest a role for fibulin-3 in tissue maintenance and regeneration in the adult olfactory pathway.

Fibulin 3 (FBLN3) Protein Profile

Protein Summary

This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.

Alternative names and synonyms associated with Fibulin 3 (FBLN3)

  • EGF containing fibulin-like extracellular matrix protein 1 (EFEMP1)
  • EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1)
  • epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (Efemp1)
  • DHRD protein
  • DRAD protein
  • FBLN3 protein
  • FBNL protein
  • FIBL-3 protein
  • MLVT protein
  • MTLV protein
  • S1-5 protein
  • T16 protein

Protein level used designations for Fibulin 3 Proteins (FBLN3)

EGF-containing fibulin-like extracellular matrix protein 1 , extracellular protein S1-5 , fibulin-3 , FIBL-3 , epidermal growth factor-containing fibulin-like extracellular matrix protein 1

2202 Homo sapiens
428543 Gallus gallus
474604 Canis lupus familiaris
511566 Bos taurus
305604 Rattus norvegicus
216616 Mus musculus
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