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anti-Human SOX9 Antibodies:
anti-Rat (Rattus) SOX9 Antibodies:
anti-Mouse (Murine) SOX9 Antibodies:
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Human Polyclonal SOX9 Primary Antibody for ICC, IF - ABIN4355424
Vestentoft, Jelnes, Hopkinson, Vainer, Møllgård, Quistorff, Bisgaard: Three-dimensional reconstructions of intrahepatic bile duct tubulogenesis in human liver. in BMC developmental biology 2011
Show all 10 Pubmed References
Human Polyclonal SOX9 Primary Antibody for IF (p), IHC (p) - ABIN754963
Papaioannou, Mirzamohammadi, Lisse, Nishimori, Wein, Kobayashi: MicroRNA-140 provides robustness to the regulation of hypertrophic chondrocyte differentiation by the PTHrP-HDAC4 pathway. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014
Show all 6 Pubmed References
Human Monoclonal SOX9 Primary Antibody for IF, IHC (p) - ABIN520382
Hodgin, Borczuk, Nasr, Markowitz, Nair, Martini, Eichinger, Vining, Berthier, Kretzler, DAgati: A molecular profile of focal segmental glomerulosclerosis from formalin-fixed, paraffin-embedded tissue. in The American journal of pathology 2010
Show all 4 Pubmed References
Human Monoclonal SOX9 Primary Antibody for ICC, ELISA - ABIN969568
Dupasquier, Abdel-Samad, Glazer, Bastide, Jay, Joubert, Cavaillès, Blache, Quittau-Prévostel: A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium. in Journal of cell science 2009
Show all 2 Pubmed References
Zebrafish Polyclonal SOX9 Primary Antibody for ELISA - ABIN408740
Yan, Willoughby, Liu, Crump, Wilson, Miller, Singer, Kimmel, Westerfield, Postlethwait: A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development. in Development (Cambridge, England) 2005
Human Polyclonal SOX9 Primary Antibody for IF, IHC (p) - ABIN272082
Zhang, Ding, Nie, Li-Ling, Zhang, Zhang, Chen, Li, Ding: Association of hsa-miR‑145 overexpression in human testicular cells with male infertility. in Molecular medicine reports 2015
Human Monoclonal SOX9 Primary Antibody for ELISA, WB - ABIN562960
Wainwright, Svingen, Ng, Wicking, Koopman: Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice. in Developmental biology 2014
Cow (Bovine) Polyclonal SOX9 Primary Antibody for FACS, WB - ABIN2780338
Vidal, Ortonne, Schedl: SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. in Journal of cutaneous pathology 2008
Show all 2 Pubmed References
Amphibian Polyclonal SOX9 Primary Antibody for DB, IHC - ABIN4355422
Sharma, Knowell, Chinaranagari, Komaragiri, Nagappan, Patel, Havrda, Chaudhary: Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN. in Molecular cancer 2014
Cat (Feline) Polyclonal SOX9 Primary Antibody for IHC (p), SimWes - ABIN4355427
Antunes, Tsaryk, Gonçalves, Pereira, Landes, Brochhausen, Ghanaati, Barbosa, Kirkpatrick: Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells. in Tissue engineering. Part A 2015
Sox9 and Ngn3 (show NEUROG3 Antibodies), key transcription factors associated with pancreatic development.
Expression of bone morphogenetic protein (BMP) 4, an upstream stimulator of SOX9, was upregulated by CG.
Xenogeneic implantation of Sox9-overexpressing hUCMSCs embedded in the BMG/fibrin scaffolds promotes the formation of cartilage-like tissue without inducing evident host immune response. Therefore, Sox9-overexpressing hUCMSCs represent a promising cell candidate for cartilage tissue engineering.
KLF15 activates SOX9 expression directly. SOX9 is involved in KLF15 function during chondrogenic differentiation.
Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury
High SOX9 expression is associated with glioblastoma.
These findings suggest that SOX9 may play an important role in tumor progression of Renal Cell Carcinoma (show MOK Antibodies) and Bladder Cancer and it may be used as a biomarker of this malignancy.
Loss of DDRGK1 decreases SOX9 expression and causes a human skeletal dysplasia.
The expression of EVI1 (show MECOM Antibodies) and SOX9 is associated with stem cell-like and metastasis signatures, and their depletion impairs the metastatic potential of breast cancer cells. These results establish the mechanistic link between resistance to mTOR (show FRAP1 Antibodies) inhibition and cancer metastatic potential, thus enhancing our understanding of mTOR (show FRAP1 Antibodies) targeting failure
regulation of cancer stem cell via SLUG-SOX9 regulatory axis
data presented here demonstrate that the 18 bp indel in the porcine SOX9 5'-UTR (show UTS2R Antibodies) is of functional importance and may therefore indeed be a causative variation in SOX9 associated traits
HIF-1alpha (show HIF1A Antibodies) activates Sox9 expression and enhances Sox9-mediated transcriptional activity.
Concluding, this study shows that, in addition to its crucial role in testis development, Sox9, together with Sox8 (show SOX8 Antibodies) and coordinately with Dmrt1 (show DMRT1 Antibodies), also controls adult testis maintenance.
SOX9 regulation of ETV5 (show ETV5 Antibodies) contributes to the control of male fertility
Nuclear factors that bind to genomic regions with "Sertoli Cell Signature" could functionally interact with SOX9; TRIM28 (show TRIM28 Antibodies) is a new SOX9 partner in fetal testes.
Down-regulated expression of Sox9 and Dazl (show DAZL Antibodies) may play important roles in MBP (show MBP Antibodies)-induced testis injury.
Sox9 is positively regulated by mesenchymal Fgf10 (show FGF10 Antibodies), a process that requires active Erk (show EPHB2 Antibodies) signaling during salivary gland development
TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex upregulation of OPN (show SPP1 Antibodies) expression is mediated by transcription factor SOX9 in an mTOR (show FRAP1 Antibodies)-independent manner. Moreover, ablation of OPN (show SPP1 Antibodies) by deficient TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex contributed to inactivation of AKT (show AKT1 Antibodies) in TSC (show SLC12A3 Antibodies) cells
SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells
hese findings indicate that chronic overexpression of Sox9 in the uterine epithelium can induce the development of endometrial hyperplastic lesions. Thus, SOX9 expression may be a factor in the formation of endometrial cancer.
The conditional ablation of Sox9 in the genital tubercle using Shh (show SHH Antibodies)-Cre/+;Sox9(flox/flox) mice revealed no genital tubercle abnormalities, possibly due to compensation by similar Sox (show QSOX1 Antibodies) factors.
The level of SOX9 protein in the kidneys of acute kidney injury-mice is reduced and correlates inversely with increased expression of microRNA miR (show MLXIP Antibodies)-1247.
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
SRY (sex determining region Y)-box 9
, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)
, transcription factor SOX-10
, SRY (sex-determining region Y)-box 9 protein
, SRY-related HMG-box, gene 9
, transcription factor SOX-9
, SRY-box containing protein 9
, SRY-box containing gene 9
, transcription factor SOX9