Browse our HDGF Proteins (HDGF)

Full name:
Hepatoma-Derived Growth Factor Proteins (HDGF)
On are 20 Hepatoma-Derived Growth Factor (HDGF) Proteins from 9 different suppliers available. Additionally we are shipping HDGF Antibodies (84) and HDGF Kits (34) and many more products for this protein. A total of 141 HDGF products are currently listed.
AI118077, D3Ertd299e, DKFZp459H185, HDGF, HMG1L2
list all proteins Gene Name GeneID UniProt
HDGF 3068 P51858
HDGF 15191 P51859
HDGF 114499 Q8VHK7

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HDGF Proteins (HDGF) by Origin

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Human Hepatoma-Derived Growth Factor (HDGF) interaction partners

  1. functional diversity of HDGF isoforms

  2. our findings first indicate that the interaction of HDGF and beta-catenin (show CTNNB1 Proteins) may play a crucial role in tumorigenesis of synovial sarcoma.

  3. HDGF was overexpressed in hepatocellular carcinoma patients and cells.

  4. miRNA497 directly targets hepatomaderived growth factor (HDGF) in prostate cancer cells.

  5. describe two previously unknown HDGF isoforms, HDGF-B and HDGF-C, generated via alternative splicing with structurally unrelated N-terminal regions of their hath region

  6. study uncovers a novel function of HDGF as a messenger of cellular condition (alarmin) which in-turn modulates cellular function-aspects that could be used as a biomarker for ovarian cancer.

  7. HDGF and beta-catenin (show CTNNB1 Proteins) interact as a positive feedback loop, which plays an important role in carcinogenesis and progression of colorectal carcinoma.

  8. HDGF is important in promoting malignant biological behaviors, including proliferation, migration and invasion of hilar cholangiocarcinoma cells.

  9. Hepatoma-derived growth factor overexpression is involved in liver carcinogenesis.

  10. Meta-analysis results provide evidence that HDGF may be a new indicator of poor cancer prognosis.

Mouse (Murine) Hepatoma-Derived Growth Factor (HDGF) interaction partners

  1. liver cancer cell-derived HDGF can induce Foxp3 (show FOXP3 Proteins)(+) T cells; the latter has immune suppressor functions on CD8 (show CD8A Proteins)(+) T cell activities

  2. Up-regulation of hepatoma-derived growth factor facilities tumor progression in malignant melanoma.

  3. HDGF promotes tumor progression after secondary upregulation and may represent another protein fitting into the concept of non-oncogene (show RAB1A Proteins) addiction of tumor tissue.

  4. HDGF exploits the innate properties of both cell surface heparan sulfates and membrane receptor via the HATH domain to affect related cell signalling processes

  5. HDGF plays a pro-fibrogenic role during liver fibrosis in mice through activation of TGF-beta (show TGFB1 Proteins) pathway.

  6. Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus

  7. Hepatoma-derived growth factor helps regulate the hepatocyte proliferation in liver development.

  8. Increased HDGF expression is correlated with disease progression of hepatocellular carcinoma and represent a specific prognostic factor in patient with liver cancer.

  9. we investigated the role of HDGF in tumorigenesis and elucidated the mechanism of action.

  10. HDGF is a novel type of neurotrophic factor (show NTF3 Proteins) harbored in the nucleus and it functions in an autocrine manner.

Cow (Bovine) Hepatoma-Derived Growth Factor (HDGF) interaction partners

  1. HDGF is synthesized similarly by the endometrium and embryo, and it may exert embryotropic effects by autocrine and/or paracrine mechanisms.

  2. involvement of HDGF during the initiation phase of the apoptotic process downstream from an initiator Caspase (show CASP3 Proteins) and regulation of this protein by phosphorylation in the nucleus

HDGF Protein Profile

Protein Summary

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with HDGF

  • hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF)
  • hepatoma-derived growth factor (hdgf)
  • hepatoma-derived growth factor (HDGF)
  • hepatoma-derived growth factor (Hdgf)
  • hepatoma-derived growth factor (LOC100357981)
  • hepatoma-derived growth factor-like (LOC100153512)
  • hepatoma-derived growth factor-like (LOC100856751)
  • AI118077 protein
  • D3Ertd299e protein
  • DKFZp459H185 protein
  • HDGF protein
  • HMG1L2 protein

Protein level used designations for HDGF

hepatoma-derived growth factor (high-mobility group protein 1-like) , hepatoma-derived growth factor , HMG-1L2 , high mobility group protein 1-like 2

457404 Pan troglodytes
549761 Xenopus (Silurana) tropicalis
100173407 Pongo abelii
494984 Xenopus laevis
3068 Homo sapiens
15191 Mus musculus
114499 Rattus norvegicus
100357981 Oryctolagus cuniculus
100715722 Cavia porcellus
612089 Canis lupus familiaris
327953 Bos taurus
776936 Gallus gallus
101109237 Ovis aries
100153512 Sus scrofa
100856751 Canis lupus familiaris
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