Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HDGF Protein (His tag)

HDGF Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318578
  • Target See all HDGF Proteins
    HDGF (Hepatoma-Derived Growth Factor (HDGF))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 3
    • 1
    Human
    Source
    • 7
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HDGF protein is labelled with His tag.
    Purpose
    Recombinant Human HDGF Protein (His Tag)
    Sequence
    Met 1-Tyr100
    Characteristics
    Recombinant Human Hepatoma-Derived Growth Factor is produced by our E.coli expression system and the target gene encoding Met1-Tyr100 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HDGF Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, 1 mM EDTA, pH 7.5.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    HDGF (Hepatoma-Derived Growth Factor (HDGF))
    Alternative Name
    HDGF (HDGF Products)
    Synonyms
    HMG1L2 Protein, hmg1l2 Protein, HDGF Protein, DKFZp459H185 Protein, AI118077 Protein, D3Ertd299e Protein, heparin binding growth factor Protein, hepatoma-derived growth factor Protein, hepatoma-derived growth factor (high-mobility group protein 1-like) Protein, heparin binding growth factor L homeolog Protein, hepatoma-derived growth factor-like Protein, HDGF Protein, hdgf Protein, Hdgf Protein, hdgf.L Protein, LOC100357981 Protein
    Background

    Background: Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.

    Synonym: Hepatoma-Derived Growth Factor, HDGF, High Mobility Group Protein 1-Kike 2, HMG-1L2, HDGF, HMG1L2

    Molecular Weight
    12.6 kDa
    UniProt
    P51858
    Pathways
    ER-Nucleus Signaling
You are here: