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Browse our anti-NRF2 (NFE2L2) Antibodies

Full name:
anti-Nuclear Factor (erythroid-Derived 2)-Like 2 Antibodies (NFE2L2)
On are 206 Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Antibodies from 27 different suppliers available. Additionally we are shipping NRF2 Kits (30) and NRF2 Proteins (10) and many more products for this protein. A total of 256 NRF2 products are currently listed.
AI194320, NF-E2R2, nfe2l2, NRF2, wu:fc15g09, wu:fj67e03
list all antibodies Gene Name GeneID UniProt
NFE2L2 4780 Q16236
NFE2L2 18024 Q60795
NFE2L2 83619 O54968

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Most Popular Reactivities for anti-NRF2 (NFE2L2) Antibodies

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anti-Human NRF2 Antibodies:

anti-Mouse (Murine) NRF2 Antibodies:

anti-Rat (Rattus) NRF2 Antibodies:

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Top referenced anti-NRF2 Antibodies

  1. Human Polyclonal NRF2 Primary Antibody for IHC (fro), IF (p) - ABIN676673 : Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. in Free radical biology & medicine 2012 (PubMed)
    Show all 16 references for ABIN676673

  2. Human Polyclonal NRF2 Primary Antibody for IF (p), IHC (p) - ABIN737271 : Wang, Fang, Huang, Chen, Fan, Wang: The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. in Environmental toxicology and pharmacology 2013 (PubMed)
    Show all 13 references for ABIN737271

  3. Human Polyclonal NRF2 Primary Antibody for ChIP, ICC - ABIN442777 : Sullivan, Martinez-Garcia, Nguyen, Mullen, Dufour, Sudarshan, Licht, Deberardinis, Chandel: The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. in Molecular cell 2013 (PubMed)
    Show all 3 references for ABIN442777

  4. Human Polyclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1584873 : Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. in Pharmacological research : the official journal of the Italian Pharmacological Society 2012 (PubMed)
    Show all 2 references for ABIN1584873

  5. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359515 : Zhao, Sun, Zhang, Strong, Dash, Kan, Grotta, Aronowski: Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. in Stroke; a journal of cerebral circulation 2007 (PubMed)
    Show all 2 references for ABIN359515

  6. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359516 : Li, Jang, Na, Cha, Surh: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN359516

  7. Human Monoclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1724931 : Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. in Physiological genomics 2012 (PubMed)

  8. Cow (Bovine) Polyclonal NRF2 Primary Antibody for WB - ABIN2780749 : Padmanabhan, Tong, Ohta, Nakamura, Scharlock, Ohtsuji, Kang, Kobayashi, Yokoyama, Yamamoto: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. in Molecular cell 2006 (PubMed)

More Antibodies against NRF2 Interaction Partners

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.

  2. we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity

  3. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (show AKT1 Antibodies) and JNK (show MAPK8 Antibodies)/Nrf2/NQO1 (show NQO1 Antibodies) pathway.

  4. Bach1 (show BACH1 Antibodies) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Antibodies) inhibition based on its level in each tissue.

  5. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  6. The expression of nrf (show NRF1 Antibodies) genes varies temporally throughout development and nrf (show NRF1 Antibodies) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (show GABPb Antibodies).

  7. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  8. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  9. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  10. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (show HMOX1 Antibodies) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (show HMOX1 Antibodies) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Down regulation of KEAP1 (show KEAP1 Antibodies), a NRF2 (show GABPA Antibodies) inhibitor, protects primary human lung epithelial cells from cigarette-smoke-extract induced cell death in an established in vitro model of radical stress.

  2. This study concluded that pretreatment with 1,25(OH)2D3 in the presence of a high concentration of leptin (show LEP Antibodies) has a beneficial effect on HUVECs through the regulation of mediators of antioxidant activity and inflammation, such as NRF2 (show GABPA Antibodies).

  3. This review deals with the mechanisms of regulation of Nrf2 (show GABPA Antibodies) transcriptional activity and its main elements, and pharmacological approaches to activation of the Keap1 (show KEAP1 Antibodies)/Nrf2 (show GABPA Antibodies)/ARE system

  4. Promotion of GSH synthesis via the Nrf2 (show GABPA Antibodies)/Keap1pathway is important in the methylglyoxal (MG) detoxification mechanism against neuronal MG-induced carbonyl stress, and Nrf2 (show GABPA Antibodies) activators contribute to reduction in the accumulation and toxic expression of carbonyl proteins.

  5. In a live co-culture assay of BEAS-2B cells and P. aeruginosa biofilm, the quorum sensing molecule 3OC12-HSL (show LIPE Antibodies) was an important but not sole contributor to the inhibition of basal NRF2 (show GABPA Antibodies) luciferase reporter activity.

  6. NRF2 (show GABPA Antibodies) polymorphism rs6721961 showed association with hypertension in a Finnish cohort

  7. Data have revealed a novel mechanism of cellular defense involving de novo NRF2 (show GABPA Antibodies) protein translation governed by the EF1a (show EEF1A1 Antibodies) interaction with the G-quadruplex in the NRF2 (show GABPA Antibodies) 5' UTR (show UTS2R Antibodies) during oxidative stress.

  8. IL-6 (show IL6 Antibodies) promotes the activation of not only the downstream molecule STAT3 (show STAT3 Antibodies) but also the Nrf2 (show GABPA Antibodies)-antioxidant pathway.

  9. These findings indicate that the Nrf2 (show GABPA Antibodies)-mediated suppression of apoptosis and promotion of autophagy contribute to nickel-induced transformation and tumorigenesis.

  10. An inactive SMPD1 (show SMPD1 Antibodies) mutant activates NRF2 (show GABPA Antibodies) in airway epithelial cells.

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Nuclear factor-E2-related factor 2 (Nrf2) has emerged as a major determinant of antioxidant-response genes and phase II detoxifying enzymes that is protective against cellular stress.

  2. Results indicate that pterostilbene treatment attenuates glutamate (show GRIN1 Antibodies)-induced oxidative stress injury in neuronal cells via the nuclear factor erythroid 2 (NF-E2)-related factor 2 signaling pathway.

  3. Results show that in response to oxidative and electrophilic stimuli, Nrf2 massively accumulates in the nucleus, whereas the stimuli do not affect the abundance and subcellular localization f Keap1 (show KEAP1 Antibodies) and Cul3 (show CUL3 Antibodies) or the Nrf2-Keap1 (show KEAP1 Antibodies)-Cul3 (show CUL3 Antibodies) interaction and suggest that the regulation of the Nrf2 protein level during stress responses is mediated by the activity but not the composition of the Nrf2-Keap1 (show KEAP1 Antibodies)-Cul3 (show CUL3 Antibodies) complex.

  4. this study shows that the protective mechanisms of zerumbone on lipopolysaccharide-induced acute lung injury are via up-regulation of antioxidative enzymes and Nrf2/HO-1 (show HMOX1 Antibodies) pathway

  5. The results demonstrate that DATS protects against oxidative stress-induced (show SQSTM1 Antibodies) DNA damage and apoptosis in C2C12 cells in part through the activation of Nrf2-mediated TrxR1 (show TXNRD1 Antibodies) induction via the ERK (show EPHB2 Antibodies) signaling pathway.

  6. Nrf2 activity, along with HO-1 (show HMOX1 Antibodies), plays an important role in the protective effects of ischemic post-conditioning against intestinal ischemia-reperfusion-induced acute lung injury.

  7. Results suggest that SC79 compound activates Akt (show AKT1 Antibodies)-Nrf2 signaling to protect osteoblasts from dexamethasone (Dex).

  8. Estradiol influences the protein expression of autophagy and Nrf2-ARE signaling in the brain, which is linked to the pathophysiological processes of PICs and oxidative stress

  9. Nrf2-knockdown in 661W cells resulted in significant exacerbation of blue light-induced reactive oxygen species levels as well as cell death. Taken together, these findings indicate that Nrf2 is an important endogenous protective factor against oxidative stress in photoreceptor cells.

  10. Nrf2 plays an important role in protecting the myocardium from ischemic injury

NRF2 (NFE2L2) Antigen Profile

Antigen Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NRF2 (NFE2L2)

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid 2-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) antibody
  • AI194320 antibody
  • NF-E2R2 antibody
  • nfe2l2 antibody
  • NRF2 antibody
  • wu:fc15g09 antibody
  • wu:fj67e03 antibody

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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