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Browse our anti-NRF2 (NFE2L2) Antibodies

Full name:
anti-Nuclear Factor (erythroid-Derived 2)-Like 2 Antibodies (NFE2L2)
On are 212 Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Antibodies from 27 different suppliers available. Additionally we are shipping NRF2 Kits (38) and NRF2 Proteins (10) and many more products for this protein. A total of 269 NRF2 products are currently listed.
AI194320, NF-E2R2, nfe2l2, NRF2, wu:fc15g09, wu:fj67e03
list all antibodies Gene Name GeneID UniProt
NFE2L2 4780 Q16236
NFE2L2 18024 Q60795
NFE2L2 83619 O54968

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anti-Human NRF2 Antibodies:

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Top referenced anti-NRF2 Antibodies

  1. Human Polyclonal NRF2 Primary Antibody for IHC (fro), IF (p) - ABIN676673 : Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. in Free radical biology & medicine 2012 (PubMed)
    Show all 15 references for ABIN676673

  2. Human Polyclonal NRF2 Primary Antibody for IF (p), IHC (p) - ABIN737271 : Wang, Fang, Huang, Chen, Fan, Wang: The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. in Environmental toxicology and pharmacology 2013 (PubMed)
    Show all 12 references for ABIN737271

  3. Human Polyclonal NRF2 Primary Antibody for ICC, IF - ABIN4340688 : Suchocki, Misiewicz-Krzemińska, Skupińska, Niedźwiecka, Lubelska, Fijałek, Kasprzycka-Guttman: Selenitetriglicerydes affect CYP1A1 and QR activity by involvement of reactive oxygen species and Nrf2 transcription factor. in Pharmacological reports : PR 2010 (PubMed)
    Show all 3 references for ABIN4340688

  4. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359516 : Li, Jang, Na, Cha, Surh: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN359516

  5. Human Polyclonal NRF2 Primary Antibody for ChIP, ICC - ABIN442777 : Sullivan, Martinez-Garcia, Nguyen, Mullen, Dufour, Sudarshan, Licht, Deberardinis, Chandel: The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. in Molecular cell 2013 (PubMed)
    Show all 2 references for ABIN442777

  6. Human Polyclonal NRF2 Primary Antibody for EIA, WB - ABIN359515 : Zhao, Sun, Zhang, Strong, Dash, Kan, Grotta, Aronowski: Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. in Stroke; a journal of cerebral circulation 2007 (PubMed)
    Show all 2 references for ABIN359515

  7. Human Polyclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1584873 : Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. in Pharmacological research : the official journal of the Italian Pharmacological Society 2012 (PubMed)
    Show all 2 references for ABIN1584873

  8. Human Monoclonal NRF2 Primary Antibody for IHC, ELISA - ABIN1724931 : Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. in Physiological genomics 2012 (PubMed)

  9. Chicken Polyclonal NRF2 Primary Antibody for WB - ABIN2780749 : Padmanabhan, Tong, Ohta, Nakamura, Scharlock, Ohtsuji, Kang, Kobayashi, Yokoyama, Yamamoto: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. in Molecular cell 2006 (PubMed)

More Antibodies against NRF2 Interaction Partners

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (show AKT1 Antibodies) and JNK (show MAPK8 Antibodies)/Nrf2/NQO1 (show NQO1 Antibodies) pathway.

  2. Bach1 (show BACH1 Antibodies) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Antibodies) inhibition based on its level in each tissue.

  3. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  4. The expression of nrf (show NRF1 Antibodies) genes varies temporally throughout development and nrf (show NRF1 Antibodies) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (show GABPb Antibodies).

  5. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  6. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  7. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  8. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

  9. mutation of either residual cysteine residue in Keap1a (show KEAP1 Antibodies) and Keap1b disrupted the ability of Keap1 (show KEAP1 Antibodies) to repress Nrf2, indicating that the presence of either Cys (show DNAJC5 Antibodies)-273 or Cys (show DNAJC5 Antibodies)-288 is sufficient for fish Keap1 (show KEAP1 Antibodies) molecules to fully function

  10. study reports that the Keap1 (show KEAP1 Antibodies)-Nrf2 system comprises discrete sensor sites, including the Keap1 (show KEAP1 Antibodies) cysteines Cys (show DNAJC5 Antibodies)-151 and Cys (show DNAJC5 Antibodies)-273, for a variety of Nrf2-activating compounds

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (show HMOX1 Antibodies) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (show HMOX1 Antibodies) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Nrf2 (show GABPA Antibodies)-mediated drug and apoptosis resistance are important in cancer therapies and tumor recurrence.

  2. herefore, the length of treatment with Nrf2 (show GABPA Antibodies) activators and/or Trx-1 (show MLL Antibodies) has first to be studied in more detail in cardiovascular disorders. Moreover, a combination of Nrf2 (show GABPA Antibodies) activators and Trx-1 (show MLL Antibodies) should be investigated and taken into consideration.

  3. EMT (show ITK Antibodies) signalling and the KEAP1 (show KEAP1 Antibodies)/NFE2L2-axis are likely to be involved in metastatic spread of malignant melanoma and also appear to have potential interactions.

  4. Barleria lupulina contains active antiinflammatory compounds that activate the Nrf2 cell defense pathway, organize cortical actin, reduce stress fibers, and improve cell junctions in microvascular endothelial cells.

  5. Study found that Nrf2 (show GABPA Antibodies) is overexpressed in glioblastoma U251 cells and revealed novel functions for Nrf2 (show GABPA Antibodies) in the regulation of redox status and cell proliferation, and that intracellular glutathione levels and AKT (show AKT1 Antibodies) signaling are required for this process.

  6. This study is the first to demonstrate that Salidroside suppresses HUVECs cell injury induced by oxidative stress through activating the Nrf2 (show GABPA Antibodies) signaling pathway.

  7. Patients with severe preeclampsia may be protected against oxidative injury following an elevation in HO-1 (show HMOX1 Antibodies) and Nrf2 (show GABPA Antibodies) levels. Nrf2 (show GABPA Antibodies) is likely to have a synergistic effect on HO-1 (show HMOX1 Antibodies) in preeclampsia.

  8. These findings are the first to identify Nrf2 (show GABPA Antibodies) as a cell-intrinsic antifibrotic factor with key roles in maintaining extracellular matrix homeostasis and a pathogenic role in systemic sclerosis.

  9. Activation of the Nrf2 (show GABPA Antibodies) is associated with invasion of breast cancer.

  10. Ganoderic acid A is a best docked isoform which inhibits the cell proliferation, viability, migration, and reactive oxygen species and messenger RNA expression of nuclear factor erythroid 2-related factor 2 in H460 cells

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. the beneficial actions of insulin (show INS Antibodies) in diabetic nephropathy appear to be mediated, in part, by suppressing renal Nrf2 and Agt (show AGXT Antibodies) gene transcription and preventing Nrf2 stimulation of Agt (show AGXT Antibodies) expression via hnRNP F (show HNRNPF Antibodies)/K.

  2. Angiotensinogen (show AGT Antibodies)-mediated downregulation of aquaporin 1 (show AQP1 Antibodies) and Nrf2 signalling may play an important role in intrarenal renin (show REN Antibodies)-angiotensin system-induced hypertension and kidney injury.

  3. Risk of a diesel exhaust inhalation-induced immune response during lung injury is significantly higher in the Nrf2+/+ mice than in Nrf2-/- mice.

  4. this study shows that hyperin protects against cisplatin-induced acute kidney injury by activating Nrf2 signaling

  5. this study shows that oroxylin A attenuates oxidative stress and lung inflammation induced by cigarette smoking via activating Nrf2 signaling pathway

  6. These findings are the first to identify Nrf2 as a cell-intrinsic antifibrotic factor with key roles in maintaining extracellular matrix homeostasis and a pathogenic role in systemic sclerosis.

  7. this paper shows that the inhibition of inflammatory mediators by piperine in microglia cells can be reversed by transfection with Nrf2 siRNA

  8. this study shows that biochanin A protects acute liver injury by activating the Nrf2 pathway

  9. that miR (show MLXIP Antibodies)-93 antagomir alleviates ischemic injury through the nuclear factor erythroid 2-related factor (Nrf2) and heme oxygenase-1 (HO-1 (show HMOX1 Antibodies)) antioxidant pathway

  10. The present study provides insight into the function of Nrf2 in NAFLD, indicating that Nrf2 deletion may lead to hepatic IR by activation of NFkappaB, which is often associated with oxidative stress.

NRF2 (NFE2L2) Antigen Profile

Antigen Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NRF2 (NFE2L2)

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid 2-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) antibody
  • AI194320 antibody
  • NF-E2R2 antibody
  • nfe2l2 antibody
  • NRF2 antibody
  • wu:fc15g09 antibody
  • wu:fj67e03 antibody

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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