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Browse our BTK Proteins (BTK)

Full name:
Bruton Agammaglobulinemia tyrosine Kinase Proteins (BTK)
On are 18 Bruton Agammaglobulinemia tyrosine Kinase (BTK) Proteins from 10 different suppliers available. Additionally we are shipping BTK Antibodies (264) and BTK Kits (34) and many more products for this protein. A total of 331 BTK products are currently listed.
AGMX1, AI528679, AT, ATK, BPK, BTK, IMD1, PSCTK1, xid, XLA
list all proteins Gene Name GeneID UniProt
BTK 695 Q06187
BTK 12229 P35991
BTK 367901  

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BTK Proteins (BTK) by Origin

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Top referenced BTK Proteins

  1. Human BTK Protein expressed in Baculovirus infected Insect Cells - ABIN2003090 : Hashimoto, Tsukada, Matsushita, Miyawaki, Niida, Yachie, Kobayashi, Iwata, Hayakawa, Matsuoka, Tsuge, Yamadori, Kunikata, Arai, Yoshizaki, Taniguchi, Kishimoto: Identification of Bruton's tyrosine kinase (Btk) gene mutations and characterization of the derived proteins in 35 X-linked agammaglobulinemia families: a nationwide study of Btk deficiency in Japan. in Blood 1996 (PubMed)
    Show all 3 references for ABIN2003090

More Proteins for BTK Interaction Partners

Human Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. Novel BTK mutations have been described in a large cohort of North African patients with X-Linked agammagobulinemia.

  2. We report that BTK regulates B-cell and macrophage-mediated T-cell suppression in pancreas adenocarcinomas.

  3. Data show that Bruton tyrosine kinase (BTK)inhibitor Ibrutinib augments MALT lymphoma associated translocation (show MALT1 Proteins) protein (MALT1 (show MALT1 Proteins)) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC (show ABCB6 Proteins)) of diffuse large B cell lymphoma (DLBCL).

  4. BTK-C is a survival factor in prostate cancer cells.

  5. BTK RNA interference inhibits proliferation of FLT3 (show FLT3 Proteins)-ITD acute myeloid leukemia (show BCL11A Proteins) cells.

  6. Activates PKC (show PRRT2 Proteins) independent of BTK.

  7. study investigated all single-nucleotide substitution-caused amino acid variations in the kinase domain of Bruton tyrosine kinase; most disease-causing variations affect conserved and buried residues disturbing protein stability; sixty-seven percent of variations are predicted to be harmful

  8. Data show that Bruton tyrosine kinase (Btk) inhibitor PLS (show CTSC Proteins)-123 suggested a new direction to pharmacologically modulate Btk function and develop novel therapeutic drug for B-cell lymphoma treatment.

  9. FcgammaRIIB requires Btk and p38 MAPK (show MAPK14 Proteins) to mediate antigen-independent inhibition in human B cells.

  10. We found that chemoresistance was dependent on Btk and JAK2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins), which maintained CSC by inducing Sox-2 (show SOX2 Proteins) and prosurvival genes. We suggest that addition of ibrutinib to cisplatin may improve treatment outcome in ovarian cancer.

Mouse (Murine) Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. ITK (show ITK Proteins) and BTK regulate thermal homeostasis during septic response through mast cell function in mice.

  2. Btk inhibition treats TLR7 (show TLR7 Proteins)/IFN driven murine lupus

  3. we have identified a neutrophil Btk signalosome that is involved in a signaling pathway and neutrophil recruitment during sterile inflammation

  4. Data show that Bruton's tyrosine kinase knockout (Btk-/-) mice displayed severely reduced numbers of macrophages in the colon.

  5. inositol hexakisphosphate (IP6 (show GPRIN2 Proteins)), a soluble signaling molecule found in both animal and plant cells, also activates Btk.

  6. Data indicate interactions between Ets1 (show ETS1 Proteins) transcription factor and two of its important regulators: Lyn (show LYN Proteins), which maintains Ets1 (show ETS1 Proteins) expression to limit the differentiation of autoreactive plasma cells (PCs), and Btk.

  7. SH3/SH2 interaction domains of BTK binds, respectively, the DEAD-box domain of DDX41 (show DDX41 Proteins) and transmembrane region of STING.

  8. for Aspergillus fumigatus, activation of macrophage calcineurin (show PPP3CA Proteins)-NFAT (show NFATC1 Proteins) occurs via a phagosomal TLR9 (show TLR9 Proteins)-dependent and Bruton's tyrosine kinase-dependent signalling pathway that is independent of MyD88 (show MYD88 Proteins)

  9. BTK synergizes with Notch2 (show NOTCH2 Proteins) to govern marginal zone B cells in non-obese diabetic mice.

  10. Btk, Tec (show NR4A3 Proteins), Bmx (show BMX Proteins) are required for TLR-dependent signaling in many types of myeloid cells while being tissue-specific.

Cow (Bovine) Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. inositol hexakisphosphate (IP6 (show GPRIN2 Proteins)), a soluble signaling molecule found in both animal and plant cells, also activates Btk.

BTK Protein Profile

Protein Summary

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Alternative names and synonyms associated with BTK

  • Bruton agammaglobulinemia tyrosine kinase (BTK)
  • Bruton agammaglobulinemia tyrosine kinase (btk)
  • Bruton agammaglobulinemia tyrosine kinase (Btk)
  • AGMX1 protein
  • AI528679 protein
  • AT protein
  • ATK protein
  • BPK protein
  • BTK protein
  • IMD1 protein
  • PSCTK1 protein
  • xid protein
  • XLA protein

Protein level used designations for BTK

Bruton agammaglobulinemia tyrosine kinase , B-cell progenitor kinase , agammaglobulinaemia tyrosine kinase , dominant-negative kinase-deficient Brutons tyrosine kinase , tyrosine-protein kinase BTK , tyrosine-protein kinase BTK isoform (lacking exon 14) , ATK , BPK , Bruton's tyrosine kinase , Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) , X-linked immune deficiency , agammaglobulinemia tyrosine kinase , bruton tyrosine kinase , kinase EMB

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