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Browse our BTK Proteins (BTK)

Full name:
Bruton Agammaglobulinemia tyrosine Kinase Proteins (BTK)
On www.antibodies-online.com are 23 Bruton Agammaglobulinemia tyrosine Kinase (BTK) Proteins from 10 different suppliers available. Additionally we are shipping BTK Antibodies (279) and BTK Kits (39) and many more products for this protein. A total of 357 BTK products are currently listed.
Synonyms:
AGMX1, AI528679, AT, ATK, BPK, BTK, IMD1, PSCTK1, xid, XLA
list all proteins Gene Name GeneID UniProt
BTK 695 Q06187
BTK 12229 P35991
BTK 367901  

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BTK Proteins (BTK) by Origin

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Top referenced BTK Proteins

  1. Human BTK Protein expressed in Baculovirus infected Insect Cells - ABIN2003090 : Hashimoto, Tsukada, Matsushita, Miyawaki, Niida, Yachie, Kobayashi, Iwata, Hayakawa, Matsuoka, Tsuge, Yamadori, Kunikata, Arai, Yoshizaki, Taniguchi, Kishimoto: Identification of Bruton's tyrosine kinase (Btk) gene mutations and characterization of the derived proteins in 35 X-linked agammaglobulinemia families: a nationwide study of Btk deficiency in Japan. in Blood 1996 (PubMed)
    Show all 3 references for ABIN2003090

  2. Human BTK Protein expressed in Baculovirus infected Insect Cells - ABIN2003091 : Vihinen, Nore, Mattsson, Bäckesjö, Nars, Koutaniemi, Watanabe, Lester, Jones, Ochs, Smith: Missense mutations affecting a conserved cysteine pair in the TH domain of Btk. in FEBS letters 1997 (PubMed)
    Show all 3 references for ABIN2003091

More Proteins for BTK Interaction Partners

Human Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. LMP2A signaling results in STAT3 (show STAT3 Proteins) phosphorylation in B cells through a PI3K (show PIK3CA Proteins)/BTK-dependent pathway.

  2. Case Report: Btk mutation responsible for X-Linked agammaglobulinemia manifesting as Pseudomonas aeruginosa liver abscess.

  3. this review describes contributions of BTK to immune tolerance, including studies testing BTK-inhibitors for treatment of autoimmune diseases

  4. The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin.

  5. report that BTK is expressed by murine and human MDSCs, and that ibrutinib is able to inhibit BTK phosphorylation in these cells

  6. Novel BTK mutations have been described in a large cohort of North African patients with X-Linked agammagobulinemia.

  7. We report that BTK regulates B-cell and macrophage-mediated T-cell suppression in pancreas adenocarcinomas.

  8. Data show that Bruton tyrosine kinase (BTK)inhibitor Ibrutinib augments MALT lymphoma associated translocation (show MALT1 Proteins) protein (MALT1 (show MALT1 Proteins)) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC (show ABCB6 Proteins)) of diffuse large B cell lymphoma (DLBCL).

  9. BTK-C is a survival factor in prostate cancer cells.

  10. BTK RNA interference inhibits proliferation of FLT3 (show FLT3 Proteins)-ITD acute myeloid leukemia (show BCL11A Proteins) cells.

Mouse (Murine) Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. Btk and NLRP3 (show NLRP3 Proteins) co-regulate platelet activation, aggregation, and in vitro thrombus formation.The NLRP3 (show NLRP3 Proteins) inflammasome is upregulated in activated platelets.

  2. Btk inhibition ameliorated hepatocellular injury in a well-established model of liver partial warm ischemia and in situ reperfusion.

  3. report that BTK is expressed by murine and human MDSCs, and that ibrutinib is able to inhibit BTK phosphorylation in these cells

  4. ITK (show ITK Proteins) and BTK regulate thermal homeostasis during septic response through mast cell function in mice.

  5. Btk inhibition treats TLR7 (show TLR7 Proteins)/IFN driven murine lupus

  6. we have identified a neutrophil Btk signalosome that is involved in a signaling pathway and neutrophil recruitment during sterile inflammation

  7. Data show that Bruton's tyrosine kinase knockout (Btk-/-) mice displayed severely reduced numbers of macrophages in the colon.

  8. inositol hexakisphosphate (IP6 (show GPRIN2 Proteins)), a soluble signaling molecule found in both animal and plant cells, also activates Btk.

  9. Data indicate interactions between Ets1 (show ETS1 Proteins) transcription factor and two of its important regulators: Lyn (show LYN Proteins), which maintains Ets1 (show ETS1 Proteins) expression to limit the differentiation of autoreactive plasma cells (PCs), and Btk.

  10. SH3/SH2 interaction domains of BTK binds, respectively, the DEAD-box domain of DDX41 (show DDX41 Proteins) and transmembrane region of STING.

Cow (Bovine) Bruton Agammaglobulinemia tyrosine Kinase (BTK) interaction partners

  1. inositol hexakisphosphate (IP6 (show GPRIN2 Proteins)), a soluble signaling molecule found in both animal and plant cells, also activates Btk.

BTK Protein Profile

Protein Summary

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Alternative names and synonyms associated with BTK

  • Bruton agammaglobulinemia tyrosine kinase (BTK)
  • Bruton agammaglobulinemia tyrosine kinase (btk)
  • Bruton agammaglobulinemia tyrosine kinase (Btk)
  • AGMX1 protein
  • AI528679 protein
  • AT protein
  • ATK protein
  • BPK protein
  • BTK protein
  • IMD1 protein
  • PSCTK1 protein
  • xid protein
  • XLA protein

Protein level used designations for BTK

Bruton agammaglobulinemia tyrosine kinase , B-cell progenitor kinase , agammaglobulinaemia tyrosine kinase , dominant-negative kinase-deficient Brutons tyrosine kinase , tyrosine-protein kinase BTK , tyrosine-protein kinase BTK isoform (lacking exon 14) , ATK , BPK , Bruton's tyrosine kinase , Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) , X-linked immune deficiency , agammaglobulinemia tyrosine kinase , bruton tyrosine kinase , kinase EMB

GENE ID SPECIES
100057626 Equus caballus
465759 Pan troglodytes
568653 Danio rerio
703000 Macaca mulatta
100170477 Xenopus (Silurana) tropicalis
100354225 Oryctolagus cuniculus
100594539 Nomascus leucogenys
695 Homo sapiens
12229 Mus musculus
367901 Rattus norvegicus
492019 Canis lupus familiaris
100627308 Sus scrofa
533459 Bos taurus
374075 Gallus gallus
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