Browse our anti-CD86 (CD86) Antibodies

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anti-CD86 Molecule Antibodies (CD86)
On are 796 CD86 Molecule (CD86) Antibodies from 33 different suppliers available. Additionally we are shipping CD86 Kits (59) and CD86 Proteins (41) and many more products for this protein. A total of 917 CD86 products are currently listed.
B7, B7-2, B7.2, B70, Cd28l2, CD28LG2, CLS1, ETC-1, LAB72, Ly-58, Ly58, MB7, MB7-2, TS/A-2
list all antibodies Gene Name GeneID UniProt
CD86 12524 P42082
CD86 942 P42081
CD86 56822  

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All available anti-CD86 Antibodies

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Top referenced anti-CD86 Antibodies

  1. Mouse (Murine) Monoclonal CD86 Primary Antibody for FACS - ABIN371013 : Hathcock, Laszlo, Pucillo, Linsley, Hodes: Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. in The Journal of experimental medicine 1994 (PubMed)
    Show all 8 references for 371013

  2. Human Monoclonal CD86 Primary Antibody for FACS, Neut - ABIN4899735 : Sakthivel, Shively, Kakoulidou, Pearce, Lefvert: The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysm. in Journal of internal medicine 2007 (PubMed)
    Show all 7 references for 4899735

  3. Human Monoclonal CD86 Primary Antibody for FACS - ABIN1106596 : Ade, Leon, Pallardy, Peiffer, Kerdine-Romer, Tissier, Bonnet, Fabre, Ourlin: HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway. in Toxicological sciences : an official journal of the Society of Toxicology 2009 (PubMed)
    Show all 4 references for 1106596

  4. Human Polyclonal CD86 Primary Antibody for FACS, IHC - ABIN4899737 : Hock, Patton, Budhia, Mannari, Roberts, McKenzie: Human plasma contains a soluble form of CD86 which is present at elevated levels in some leukaemia patients. in Leukemia 2002 (PubMed)
    Show all 4 references for 4899737

  5. Human Monoclonal CD86 Primary Antibody for Func, FACS - ABIN1106593 : Pellat-Deceunynck, Jego, Harousseau, Vié, Bataille: Isolation of human lymphocyte antigens class I-restricted cytotoxic T lymphocytes against autologous myeloma cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 1999 (PubMed)
    Show all 3 references for 1106593

  6. Human Monoclonal CD86 Primary Antibody for FACS - ABIN1106595 : Legendre, Raphael, Gras, Lefevre, Feuillard, Dormont, Richard: CD80 expression is decreased in hyperplastic lymph nodes of HIV+ patients. in International immunology 1999 (PubMed)
    Show all 3 references for 1106595

  7. Human Monoclonal CD86 Primary Antibody for FACS - ABIN4898167 : Chiang, Ledermann, Aitkens, Benjamin, Katz, Chain: Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 references for 4898167

  8. Mouse (Murine) Polyclonal CD86 Primary Antibody for ELISA, IP - ABIN2000273 : Rau, Dieter, Luo, Priest, Baumgarth: B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

  9. Human Monoclonal CD86 Primary Antibody for FACS, IHC (fro) - ABIN319825 : Nozawa, Wachi, Tominaga, Abe, Wakasa: A novel monoclonal antibody (FUN-1) identifies an activation antigen in cells of the B-cell lineage and Reed-Sternberg cells. in The Journal of pathology 1993 (PubMed)

  10. Human Monoclonal CD86 Primary Antibody for FACS - ABIN4898163 : Kraetzel, Stoelcker, Eissner, Multhoff, Pfeifer, Holler, Schulz: NKG2D-dependent effector function of bronchial epithelium-activated alloreactive T-cells. in The European respiratory journal 2008 (PubMed)

More Antibodies against CD86 Interaction Partners

Mouse (Murine) CD86 Molecule (CD86) interaction partners

  1. B7.2 expressed on skin CD8 (show CD8A Antibodies)(+) T cells supports the survival of Tregs, likely through interaction with its receptor CTLA-4 (show CTLA4 Antibodies), which is highly expressed on skin Tregs.

  2. CTLA-4 (show CTLA4 Antibodies)(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.

  3. Low CD86 expression is associated with B16 melanoma.

  4. Local administration of CD86 siRNA during the effector phase ameliorates asthma phenotypes.

  5. Meningococcal capsular polysaccharide-loaded vaccine nanoparticles induce expression of CD86.

  6. The genetic inactivation of B7.1/B7.2 deteriorates obesity-related liver steatosis and metabolic dysregulation, likely a result of the intrinsic absence of Tregs in these mice, rendering DKO mice a novel murine model of NASH (show SAMSN1 Antibodies).

  7. data show an important role of the adaptive immune system, in particular T cell CD80 (show CD80 Antibodies)/86 costimulation molecules, in the physiological regulation of bone resorption and preservation of bone mass

  8. CD80 (show CD80 Antibodies) and CD86 costimulatory molecules regulate OT-II CD4 (show CD4 Antibodies)(+) T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice

  9. novel function of CTLA4Ig in tumor immunity and suggest that CD86 on NK cells is an activating receptor and closely involved in the CTLA4Ig-mediated anti-tumor response.

  10. The need for additional immune suppression in the intestine reflects commensal microbe-driven T-cell activation through the accessory costimulation molecules ICOSL (show ICOSLG Antibodies) and OX40L (show TNFSF4 Antibodies) in B7 deprived mice.

Human CD86 Molecule (CD86) interaction partners

  1. IL-6 (show IL6 Antibodies), DEC205 (show LY75 Antibodies), and CD86 can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.

  2. the upregulation of CD86 but not CD80 (show CD80 Antibodies) and PD-L1 (show CD274 Antibodies) on CD68 (show CD68 Antibodies)+ cells in the liver of HBV-infected patients, observed in our study, suggest that the profile of CD68 (show CD68 Antibodies)+ cells does not support the induction of proper Th1 (show TH1L Antibodies) responses that are needed to clear HBV infection. This might provide an explanation for the absence of potent HBV-specific T cells during chronic HBV infection.

  3. CD86 variants association with susceptibility to multiple sclerosis in Iranian population.

  4. B-cells from patients tolerant to the graft maintained higher IL-10 (show IL10 Antibodies) production after CD40 (show CD40 Antibodies) ligation, which correlates with lower CD86 expression compared to patients with chronic rejection.

  5. TLR2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies) and CD86 gene polymorphisms are associated with Recurrent aphthous stomatitis.

  6. The SNP CD40 (show CD40 Antibodies) -1C>T was associated with the IgG response against PvDBP, whereas IgG antibody titers against PvMSP-119 were influenced by the polymorphism CD86 +1057G>A.

  7. PD-L1 (show CD274 Antibodies) expression and the PD-L1 (show CD274 Antibodies)/CD86 ratio in CD14 (show NDUFA2 Antibodies)(++)CD16 (show CD16 Antibodies)(+) monocytes were higher during chronic hepatitis C virus infection.

  8. Data show that induction of CD86 antigen expression on monocytes by human beta Defensin-3 (hBD-3 (show DEFB103A Antibodies)) is suppressed by P2X7 purinoceptor (P2X7R (show P2RX7 Antibodies)) antagonist.

  9. analysis of the expression of TLR-9 (show TLR9 Antibodies), CD86, and CD95 (show FAS Antibodies) in circulating B cells of patients with chronic viral hepatitis B or C before and after antiviral therapy

  10. Polymorphisms in CD86 gene have diverse effects on the pathogenesis of pneumonia-induced sepsis.

Pig (Porcine) CD86 Molecule (CD86) interaction partners

  1. Reduced CD86 antigen is associated with melanoma.

  2. The complete cDNA encoding CD86 molecule of miniature swine was cloned, sequenced and analyzed.

Cow (Bovine) CD86 Molecule (CD86) interaction partners

  1. Northern analysis revealed CD80 (show CD80 Antibodies) and CD86 mRNAs in luteal tissue, with greatest steady-state concentrations at midcycle

CD86 Antigen Profile

Antigen Summary

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Alternative names and synonyms associated with CD86

  • CD86 molecule (CD86) antibody
  • CD86 antigen (Cd86) antibody
  • CD86 molecule (Cd86) antibody
  • CD86/B7-2 costimulatory molecule (LOC554318) antibody
  • B7 antibody
  • B7-2 antibody
  • B7.2 antibody
  • B70 antibody
  • Cd28l2 antibody
  • CD28LG2 antibody
  • CLS1 antibody
  • ETC-1 antibody
  • LAB72 antibody
  • Ly-58 antibody
  • Ly58 antibody
  • MB7 antibody
  • MB7-2 antibody
  • TS/A-2 antibody

Protein level used designations for anti-CD86 Molecule (CD86) Antibodies

CD86 antigen , T-lymphocyte activation antigen CD86 , activation B7-2 antigen , early T cell costimulatory molecule-1 , early T-cell costimulatory molecule 1 , B-lymphocyte activation antigen B7-2 , BU63 , CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) , CTLA-4 counter-receptor B7.2 , FUN-1 , cd86 antigen , membrane glycoprotein , B7-2 protein , co-stimulatory molecule B7-2 , costimulatory molecule , CD86/B7-2 costimulatory molecule , B7-1 costimulatory molecule

470900 Pan troglodytes
493704 Felis catus
714390 Macaca mulatta
12524 Mus musculus
942 Homo sapiens
56822 Rattus norvegicus
403764 Canis lupus familiaris
397441 Sus scrofa
414345 Bos taurus
100008999 Oryctolagus cuniculus
554318 Ovis aries
Selected quality suppliers for anti-CD86 (CD86) Antibodies
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