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Browse our Klotho (KL) ELISA Kits

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Klotho ELISA Kits (KL)
On are 40 Klotho (KL) ELISA Kits from 7 different suppliers available. Additionally we are shipping Klotho Antibodies (95) and Klotho Proteins (13) and many more products for this protein. A total of 163 Klotho products are currently listed.
alpha-kl, Kitl, KL, LOC100223456

Top referenced Klotho ELISA Kits

  1. Human KL ELISA Kit for Sandwich ELISA - ABIN457026 : Devaraj, Syed, Chien, Jialal: Validation of an immunoassay for soluble Klotho protein: decreased levels in diabetes and increased levels in chronic kidney disease. in American journal of clinical pathology 2012 (PubMed)
    Show all 12 references for ABIN457026

  2. Mouse (Murine) KL ELISA Kit for Sandwich ELISA - ABIN578431 : Andrukhova, Smorodchenko, Egerbacher, Streicher, Zeitz, Goetz, Shalhoub, Mohammadi, Pohl, Lanske, Erben: FGF23 promotes renal calcium reabsorption through the TRPV5 channel. in The EMBO journal 2014 (PubMed)

More ELISA Kits for Klotho Interaction Partners

Human Klotho (KL) interaction partners

  1. Data suggest that down-regulation of serum Klotho level may play role in development of atherosclerosis and endothelial dysfunction in subjects with type 1 diabetes.

  2. The data suggest that secreted Klotho protein attenuates the osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro through FGFR1 (show FGFR1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) signaling.

  3. Data revealed the existence of a moderating effect between Klotho and STC1 (show STC1 ELISA Kits), where Klotho may inhibit thyroid tumor progression by inhibiting the tumor marker level of STC1 (show STC1 ELISA Kits).

  4. Among cardiac patients with preserved left ventricular ejection fraction, serum alpha-Klotho concentrations but not FGF23 (show FGF23 ELISA Kits) concentrations were negatively associated with diastolic dysfunction.

  5. KLOTHO G-395A polymorphism associates with reduced cognitive impairment in a sample of Chinese nonagenarians and centenarians.

  6. serum FGF23 (show FGF23 ELISA Kits) was positively associated with coronary artery calcification in women and serum alpha-Klotho was positively associated with aortic valve calcification in men, independent of the confounding variables

  7. The -395A allele of the KLOTHO gene may be a protective genetic factor for hypertension in the Chinese population.

  8. The -395A allele carriers of the Klotho gene were correlated with lower risk of metabolic syndrome in a Chinese elderly population.

  9. Full-length, membrane-bound Klotho is not expressed in healthy or uraemic human vascular tissue.

  10. analysis of longitudinal associations between baseline s-klotho and FGF23 concentrations and mortality reveals that FGF23, but not klotho, may have a role in excess mortality in cardiovascular disease in those with normal kidney function

Mouse (Murine) Klotho (KL) interaction partners

  1. Inhibition of mTOR (show FRAP1 ELISA Kits) signaling ameliorates vascular calcification via Klotho upregulation.

  2. Klotho deficiency promoted HFD-induced arterial stiffening and hypertension via downregulation of AMPKalpha (show GRK4 ELISA Kits) activity.

  3. level of spontaneous remyelination was increased approximately two-fold in Klotho-overexpressing mice following cuprizone-induced demyelination.

  4. data highlight the importance of ASK1 (show MAP3K5 ELISA Kits)/p38 MAPK (show MAPK14 ELISA Kits) pathway in the brain and identify Klotho as a possible anti-oxidant effector

  5. Klotho ameliorates kidney injury and fibrosis and normalizes blood pressure by targeting the renin (show REN ELISA Kits)-angiotensin system.

  6. Injection of klotho protein results in hematopoietic changes opposite to the ones observed in Klotho(-/-) mice.

  7. Sodium bicarbonate administration has a favorable influence on vascular calcification and early death of klotho-deficient mice.

  8. Data suggest that the level of expression of Klotho in pancreatic beta-cells regulates apoptosis; low expression (halplodeficiency of Klotho) promotes apoptosis/type 1 diabetes; beta-cell-specific overexpression prevents apoptosis/type 1 diabetes.

  9. p16(INK4a) plays a previously unrecognized role in downregulating alpha-klotho expression during ageing.

  10. Klotho deficiency-induced arterial stiffening may involve aldosterone-mediated upregulation of scleraxis and induction of autophagy, which led to increased collagen-1 expression and decreased elastin (show ELN ELISA Kits) levels, respectively.

Pig (Porcine) Klotho (KL) interaction partners

  1. significant expression of FGF23 (show FGF23 ELISA Kits) and KL within the growth plate and adjacent tissues imply a potential local role of FGF23 (show FGF23 ELISA Kits) in chondrocyte differentiation and tissue mineralization.

Klotho (KL) Antigen Profile

Antigen Summary

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.

Alternative names and synonyms associated with Klotho (KL)

  • klotho (KL) Elisa Kit
  • klotho (LOC100223456) Elisa Kit
  • klotho (kl) Elisa Kit
  • klotho (LOC100533542) Elisa Kit
  • klotho (Kl) Elisa Kit
  • Klotho (Kl) Elisa Kit
  • Klotho-like (LOC100356074) Elisa Kit
  • alpha-kl Elisa Kit
  • Kitl Elisa Kit
  • KL Elisa Kit
  • LOC100223456 Elisa Kit

Protein level used designations for Klotho (KL) ELISA Kits

klotho , kit ligand , secreted form of Klotho protein

467257 Pan troglodytes
100009028 Oryctolagus cuniculus
100223456 Taeniopygia guttata
100490988 Xenopus (Silurana) tropicalis
100533542 Aplysia californica
9365 Homo sapiens
16591 Mus musculus
83504 Rattus norvegicus
100685604 Canis lupus familiaris
100519728 Sus scrofa
784635 Bos taurus
100714519 Cavia porcellus
418909 Gallus gallus
101110249 Ovis aries
100356074 Oryctolagus cuniculus
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