You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our PDGFRB Proteins (PDGFRB)

Full name:
Platelet-Derived Growth Factor Receptor, beta Polypeptide Proteins (PDGFRB)
On www.antibodies-online.com are 36 Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) Proteins from 13 different suppliers available. Additionally we are shipping PDGFRB Antibodies (425) and PDGFRB Kits (33) and many more products for this protein. A total of 534 PDGFRB products are currently listed.
Synonyms:
AI528809, CD140B, IBGC4, JTK12, PDGFR, PDGFR-1, PDGFR1
list all proteins Gene Name GeneID UniProt
PDGFRB 18596 P05622
PDGFRB 24629 Q05030
PDGFRB 5159 P09619

Show all synonyms

PDGFRB Proteins (PDGFRB) by Origin

Select your origin of interest

Top referenced PDGFRB Proteins

  1. Human PDGFRB Protein expressed in Human Cells - ABIN2002983 : Chi, McPhee, Wagner, Dietz, Pantazis, Goustin: Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity. in Oncogene 1997 (PubMed)
    Show all 4 references for ABIN2002983

  2. Cynomolgus PDGFRB Protein expressed in Human Cells - ABIN2010002 : Arcaro, Zvelebil, Wallasch, Ullrich, Waterfield, Domin: Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. in Molecular and cellular biology 2000 (PubMed)
    Show all 4 references for ABIN2010002

  3. Rat (Rattus) PDGFRB Protein expressed in Human Cells - ABIN2009522 : Zhang, Henzel: Signal peptide prediction based on analysis of experimentally verified cleavage sites. in Protein science : a publication of the Protein Society 2004 (PubMed)
    Show all 4 references for ABIN2009522

  4. Human PDGFRB Protein expressed in Human Cells - ABIN2002985 : Morerio, Acquila, Rosanda, Rapella, Dufour, Locatelli, Maserati, Pasquali, Panarello: HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2). in Cancer research 2004 (PubMed)
    Show all 4 references for ABIN2002985

  5. Human PDGFRB Protein expressed in HEK-293 Cells - ABIN2181629 : Golub, Barker, Lovett, Gilliland: Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. in Cell 1994 (PubMed)
    Show all 3 references for ABIN2181629

More Proteins for PDGFRB Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) interaction partners

  1. Results suggested that increased bFGF (show FGF2 Proteins) upregulates the expression of PDGFRbeta and may enhance PDGFRbeta-mediated pericyte functions after brain ischemia

  2. Laminin regulates PDGFRbeta cell differentiation, fate determination, cell stemness and muscle development via gpihbp1 (show GPIHBP1 Proteins).

  3. The role of the S1PR3 (show S1PR3 Proteins)/PDGFR-beta/Akt (show AKT1 Proteins) pathway in sphingosine-1-phosphate -induced endothelial progenitor cells migration and angiogenesis

  4. loss-of-function mutations in PDGFB (show PDGFB Proteins) or PDGFRB cause Primary Familial Brain Calcification.

  5. PDGF (show PDGFA Proteins) signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.

  6. This study demonstrated that PDGFRbeta-expressing cells appear to arise from vascular wall pericytes in peri (show POSTN Proteins)-infarct areas and then extend toward the ischemic core while producing ECM (show MMRN1 Proteins) proteins, fibronectin (show FN1 Proteins) and collagen type I, after MCAO.

  7. The study shows that PDGFRB and FGFR2 (show FGFR2 Proteins) mediate endothelial cell differentiation capability of triple negative breast carcinoma.

  8. Identification of a PEDF (show SERPINF1 Proteins) signaling mechanism involving PPARG (show PPARG Proteins) induction, suppression of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling and down-regulation of the PDGFRA (show PDGFRA Proteins)/B.

  9. Radial glia require PDGFD (show PDGFD Proteins)-PDGFRbeta signalling in human but not mouse neocortex

  10. The study demonstrates changes in pericyte expression of NG2 (show Vcan Proteins) and PDGFRB and vascular permeability in the sensory circumventricular organs by chronic osmotic stimulation.

Human Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) interaction partners

  1. Results suggested that increased bFGF (show FGF2 Proteins) upregulates the expression of PDGFRbeta and may enhance PDGFRbeta-mediated pericyte functions after brain ischemia

  2. Data suggest that cross-talk between PDGFb (show PDGFB Proteins)-dependent beta-catenin (show CTNNB1 Proteins) activation and Wnt (show WNT2 Proteins) signaling increases pulmonary artery smooth muscle cell proliferation in idiopathic pulmonary arterial hypertension; proliferation is not increased in normal cells.

  3. The KIT and PDGFRB mutations were predicted to be pathogenic using in silico analysis, whereas the ERBB2 (show ERBB2 Proteins) mutation was predicted to be benign.. the patient was treated with pazopanib and achieved a partial response that lasted for 7.5 months

  4. These molecular insights confirm that mutant PDGFRB is indeed the driver mutation in PDGFRB rearranged myeloid neoplasms, consistent with the robust treatment responses with imatinib.

  5. Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. Three causative genes have been identified: SLC20A2, PDGFRB and, recently, PDGFB, whose associated phenotype has not yet been extensively studied.

  6. loss-of-function mutations in PDGFB (show PDGFB Proteins) or PDGFRB cause Primary Familial Brain Calcification.

  7. Soluble platelet-derived growth factor receptor-beta is a biomarker of brain pericyte injury and blood-brain barrier dysfunction.

  8. Electron microscopy structure of PDGFRB [a full-length human platelet-derived growth factor receptor (show PDGFRL Proteins)], in complex with its ligand PDGF-B (show PDGFB Proteins).

  9. Data identify PDGFRbeta as the hub gene in both inflammatory (IBC) and non-inflammatory breast neoplasm (non-IBC) and SUMO1 (show SUMO1 Proteins) and COL1A1 (show COL1A1 Proteins) the respective key genes for IBC and non-IBC suggesting they might play important role in the pathogenesis of the neoplasm.

  10. High expression of PDGFRB is associated with clear cell renal cell carcinoma (show MOK Proteins).

PDGFRB Protein Profile

Protein Summary

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor\; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Alternative names and synonyms associated with PDGFRB

  • platelet derived growth factor receptor, beta polypeptide (Pdgfrb)
  • platelet-derived growth factor receptor, beta polypeptide (PDGFRB)
  • AI528809 protein
  • CD140B protein
  • IBGC4 protein
  • JTK12 protein
  • PDGFR protein
  • PDGFR-1 protein
  • PDGFR1 protein

Protein level used designations for PDGFRB

CD140 antigen-like family member B , PDGF beta chain , PDGF-R-beta , PDGFR-beta , beta platelet-derived growth factor receptor , beta-type platelet-derived growth factor receptor , platelet-derived growth factor receptor 1 , platelet-derived growth factor receptor beta , platelet-derived growth factor receptor beta variant 1 , Platelet-derived growth factor receptor, beta , protein tyrosin kinase

GENE ID SPECIES
18596 Mus musculus
24629 Rattus norvegicus
5159 Homo sapiens
442985 Canis lupus familiaris
770488 Gallus gallus
100342872 Oryctolagus cuniculus
Selected quality suppliers for PDGFRB Proteins (PDGFRB)
Did you look for something else?