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RPTOR Independent Companion of MTOR, Complex 2 ELISA Kits (RICTOR)
On are 5 RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) ELISA Kits from 2 different suppliers available. Additionally we are shipping RICTOR Antibodies (193) and and many more products for this protein. A total of 209 RICTOR products are currently listed.
4921505C17Rik, 6030405M08Rik, AVO3, AW492497, D530039E11Rik, Fyb, mAVO3, PIA
list all ELISA KIts Gene Name GeneID UniProt
RICTOR 253260 Q6R327
RICTOR 78757 Q6QI06
Rat RICTOR RICTOR 310131  

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Human RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. miR (show MLXIP ELISA Kits)-153 downregulation could be one important reason of Rictor upregulation and mTORC2 (show CRTC2 ELISA Kits) over-activation in glioma cells. Further, miR (show MLXIP ELISA Kits)-153-induced anti-glioma cell activity is possibly via downregulating Rictor.

  2. These results point to an increase in total and phosphorylated Akt (show AKT1 ELISA Kits) in high-grade gliomas and to a possible role of RICTOR in proliferations of high-grade glioblastomas cells.

  3. Hgh mTOR (show FRAP1 ELISA Kits) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor (show RPTOR ELISA Kits) expression evaluation revealed even stronger statistical correlation with prognosis.

  4. In this study we began by validating the expression of four main mTOR (show FRAP1 ELISA Kits) pathway components, mTOR (show FRAP1 ELISA Kits), DEPTOR (show DEPTOR ELISA Kits), rictor and raptor (show RPTOR ELISA Kits), at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  5. Based on univariate and multivariate Cox (show COX8A ELISA Kits) proportional hazards regression analysis, RICTOR-positive expression, AJCC staging III or IV and nodal metastasis are prognostic factors and the former two are independent risk factors for esophageal squamous cell carcinoma.

  6. Taken together, our results suggest that the proinflammatory cytokine TNFalpha promotes the expression of Rictor through the NF-kappaB pathway in renal cell carcinoma.

  7. RICTOR amplification may define a novel and unique molecular subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors.

  8. Data show that rapamycin-insensitive companion of mTOR protein (RICTOR) plays a central role in phosphatidylinositol 3-kinase (PI3K (show PIK3CA ELISA Kits))/proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-akt (AKT (show AKT1 ELISA Kits)) pathway in melanocytes and its deregulation could be involved in melanoma development.

  9. Mdm20 (show NAA25 ELISA Kits) acts as a novel regulator of Rictor, thereby controlling mTORC2 (show CRTC2 ELISA Kits) activity, and leading to the activation of PKCalphaS657 and FoxO1 (show FOXO1 ELISA Kits).

  10. RICTOR/MTORC2 (show CRTC2 ELISA Kits)-AKT (show AKT1 ELISA Kits) can integrate convergent hormonal and metabolic signals to provide coordinated and sensitive regulation of hepatic FOXO1 (show FOXO1 ELISA Kits)-target gene expression.

Mouse (Murine) RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. our present findings highlighted a pivotal regulatory axis of Rictor-FoxO3a (show FOXO3 ELISA Kits) in maintaining quiescence and the stemness of LSCs.

  2. These findings reveal a novel functional pathway important for age-related bone loss and support for miR (show MLXIP ELISA Kits)-218 and Rictor as potential targets for therapeutic intervention for age-related osteoporosis treatment.

  3. this study shows that Rictor is required for NKT (show CTSL1 ELISA Kits)-17 cell development and normal iNKT-cell cytolytic function

  4. data suggest that Rictor/mTORC2 (show CRTC2 ELISA Kits) controls an amino acid-sensitive checkpoint that allows T cells to determine whether the microenvironment contains sufficient resources for daughter cell generation.

  5. Loss of DNMT3B (show DNMT3B ELISA Kits) results in hypomethylation of the miR (show MLXIP ELISA Kits)-196b promoter and increased miR (show MLXIP ELISA Kits)-196b expression, which directly targets the mTORC2 (show CRTC2 ELISA Kits) component Rictor.

  6. Rictor in the limb mesenchymal lineage is required for the normal response to the anti-sclerostin (show SOST ELISA Kits) therapy in both bone formation and resorption.

  7. Low RICTOR expression was detected in quiescent, confluent mouse aortic endothelial cells, whereas high doses of FGF2 (show FGF2 ELISA Kits) induced high RICTOR expression that was associated with strong mTORC2 (show CRTC2 ELISA Kits)-specific protein kinase (show CDK7 ELISA Kits) Ca and AKT (show AKT1 ELISA Kits) phosphorylation

  8. analysis of mTORC2 (show CRTC2 ELISA Kits) components mTOR (show FRAP1 ELISA Kits), Rictor and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  9. Adipose tissue mTORC2 (show CRTC2 ELISA Kits) regulates via Rictor ChREBP (show MLXIPL ELISA Kits)-driven de novo lipogenesis and hepatic glucose metabolism.

  10. Rictor is essential for the generation of type II IFN-dependent antiviral and antiproliferative responses and that it controls the generation of type II IFN-suppressive effects on normal and malignant hematopoiesis

RICTOR Antigen Profile

Antigen Summary

RICTOR and MTOR (FRAP1\; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004

Alternative names and synonyms associated with RICTOR

  • RPTOR independent companion of MTOR, complex 2 (RICTOR) Elisa Kit
  • rapamycin-insensitive companion of mTOR (LOC100357138) Elisa Kit
  • RPTOR independent companion of MTOR, complex 2 (Rictor) Elisa Kit
  • 4921505C17Rik Elisa Kit
  • 6030405M08Rik Elisa Kit
  • AVO3 Elisa Kit
  • AW492497 Elisa Kit
  • D530039E11Rik Elisa Kit
  • Fyb Elisa Kit
  • mAVO3 Elisa Kit
  • PIA Elisa Kit

Protein level used designations for RICTOR

rapamycin-insensitive companion of mTOR , AVO3 homolog , TORC2-specific protein AVO3 , hAVO3 , pianissimo , mAVO3 , protein pianissimo , FYN binding protein , rapamycin insensitive companion of mTOR

694915 Macaca mulatta
100357138 Oryctolagus cuniculus
253260 Homo sapiens
78757 Mus musculus
479356 Canis lupus familiaris
310131 Rattus norvegicus
527459 Bos taurus
100519575 Sus scrofa
100715888 Cavia porcellus
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