You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Spleen tyrosine Kinase Proteins (SYK)

Full name:
Spleen tyrosine Kinase Proteins (SYK)
On www.antibodies-online.com are 13 Spleen tyrosine Kinase (SYK) Proteins from 9 different suppliers available. Additionally we are shipping Spleen tyrosine Kinase Antibodies (367) and Spleen tyrosine Kinase Kits (35) and many more products for this protein. A total of 439 Spleen tyrosine Kinase products are currently listed.
Synonyms:
p72-Syk, p72syk, Sykb
list all proteins Gene Name GeneID UniProt
SYK 6850 P43405
SYK 20963 P48025
SYK 25155 Q64725

Show all synonyms

Spleen tyrosine Kinase Proteins (SYK) by Origin

Select your origin of interest

More Proteins for Spleen tyrosine Kinase Interaction Partners

Human Spleen tyrosine Kinase (SYK) interaction partners

  1. TNF (show TNF Proteins) activates Mule (show HUWE1 Proteins) by inducing the dissociation of Mule (show HUWE1 Proteins) from its inhibitor ARF. Inhibition of Mule (show HUWE1 Proteins) phosphorylation by silencing Syk prevents this, thereby inhibiting Mule (show HUWE1 Proteins) E3 ligase activity and TNF (show TNF Proteins)-induced JNK (show MAPK8 Proteins) activation and cell death.

  2. Study establishes P-SYK as a critical biomarker in AML (show RUNX1 Proteins) that identifies tumors sensitive to SYK inhibition, identifies an at-risk patient population, and allows for the monitoring of target inhibition during treatment.

  3. LMPs are important pro-apoptotic regulators for Rb cells through reduction of SYK expression.

  4. Data suggest that immune complexes (ICs (show DNAI1 Proteins)) of FCGR3A (show CD16 Proteins)-SYK play critical role in activation of CD4 (show CD4 Proteins)+ T-cells and thus in modulation of adaptive immunity; such ICs (show DNAI1 Proteins) are present in blood from patients with systemic lupus erythematosus.

  5. Syk activation is prominent in infiltrating myeloid cells in human rapidly progressive glomerulonephritis

  6. Results suggest that the activated Syk-mediated TRAF6 (show TRAF6 Proteins) pathway leads to aberrant activation of B cells in SLE.

  7. this study shows that the treatment of cells with inducers of stress granule formation leads to the recruitment of Syk to these protein-RNA complexes

  8. The differential requirements of ZAP70 (show ZAP70 Proteins) and SYK during thymic development.

  9. these data support the translation of approaches targeting Syk with fostamatinib to the clinic for patients with relapsed and possibly even newly diagnosed Waldenstrom macroglobulinemia

  10. Syk is constitutively associated with TLR4 (show TLR4 Proteins).

Mouse (Murine) Spleen tyrosine Kinase (SYK) interaction partners

  1. Dectin-1 (show CLEC7A Proteins) and Dectin-2 (show CLEC6A Proteins) seem not to play a major role in Borrelia recognition or Borrelia-induced inflammation. However, Syk seems to be involved in Borrelia-induced cytokine production

  2. TNF (show TNF Proteins) activates Mule by inducing the dissociation of Mule from its inhibitor ARF. Inhibition of Mule phosphorylation by silencing Syk prevents this, thereby inhibiting Mule E3 ligase activity and TNF (show TNF Proteins)-induced JNK (show MAPK8 Proteins) activation and cell death.

  3. The effects of OXSI-2 identified in this study provide context for the role of Syk in inflammasome signaling and demonstrate its importance in oxidative signaling upstream of inflammasome activation and downstream of ion flux.

  4. Mincle (show CLEC4E Proteins) Activation and the Syk/Card9 (show CARD9 Proteins) Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

  5. Syk deletion in myeloid cells is protective in mouse nephrotoxic serum nephritis.

  6. Src (show SRC Proteins)/Syk-dependent signalling stabilises platelet adhesion to podoplanin (show PDPN Proteins)

  7. These results provide new insights into the mechanisms by which SYK regulates MHC-II expression via autophagy in macrophages.

  8. Syk mediates airway contractility in the normal and allergic airways, independent of its role and function in leukocytes, and supports a paracrine role for airway epithelial Syk in modulating airway smooth muscle activity.

  9. Syk expression by DCs is necessary for IL-23p19 (show IL23A Proteins) production in response to C. albicans

  10. The Syk inhibitor fostamatinib prevented bleomycin-induced fibrosis and inflammation in the skin and in the lung. The anti-fibrotic effect of fostamatinib is linked to reduced Syk phosphorylation and TGF-beta (show TGFB1 Proteins) expression.

Cow (Bovine) Spleen tyrosine Kinase (SYK) interaction partners

  1. These data suggest that Syk mRNA expression dynamics is closely related to bovine leukemia virus-induced disease.

Spleen tyrosine Kinase (SYK) Protein Profile

Protein Summary

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen tyrosine Kinase (SYK)

  • Tyrosine-protein kinase SYK (ksyk)
  • spleen tyrosine kinase (SYK)
  • spleen tyrosine kinase (Syk)
  • p72-Syk protein
  • p72syk protein
  • Sykb protein

Protein level used designations for Spleen tyrosine Kinase Proteins (SYK)

Tyrosine-protein kinase SYK , tyrosine-protein kinase SYK , protein-tyrosine kinase

GENE ID SPECIES
100380388 Salmo salar
6850 Homo sapiens
20963 Mus musculus
25155 Rattus norvegicus
484196 Canis lupus familiaris
100125540 Sus scrofa
515515 Bos taurus
427272 Gallus gallus
100716985 Cavia porcellus
100345556 Oryctolagus cuniculus
Selected quality suppliers for Spleen tyrosine Kinase Proteins (SYK)
Did you look for something else?