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Browse our Spleen tyrosine Kinase Proteins (SYK)

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Spleen tyrosine Kinase Proteins (SYK)
On are 13 Spleen tyrosine Kinase (SYK) Proteins from 9 different suppliers available. Additionally we are shipping Spleen tyrosine Kinase Antibodies (376) and Spleen tyrosine Kinase Kits (46) and many more products for this protein. A total of 458 Spleen tyrosine Kinase products are currently listed.
p72-Syk, p72syk, Sykb
list all proteins Gene Name GeneID UniProt
SYK 6850 P43405
SYK 20963 P48025
SYK 25155 Q64725

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Spleen tyrosine Kinase Proteins (SYK) by Origin

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Human Spleen tyrosine Kinase (SYK) interaction partners

  1. Pharmacological inhibitors of SYK activity significantly reduced the engulfment of oxLDL microbeads in the presence of serum factors, but had little effect on IgG phagocytosis.

  2. our data strongly suggest that AQCA-mediated suppression of inflammatory responses could be managed by a direct interference of signaling cascades including IRAK (show IRAK1 Proteins) and Syk, linked to the activation of NF-kappaB (show NFKB1 Proteins) and AP-1 (show FOSB Proteins).

  3. a potential link between the upregulation of Syk and VEGF-C (show VEGFC Proteins) expression and lung adenocarcinoma.

  4. The lack of Syk mRNA expression in lung cancer play an important role in angiogenesis.

  5. Overall novel mutations in SYK gene and in silico analysis revealed that these mutations are crucial and might be responsible for altered expression of SYK.

  6. this study shows that SYK increased MUC5AC expression via ERK2 (show MAPK1 Proteins) and p38 MAPK (show MAPK14 Proteins) signaling pathways in airway epithelial cells

  7. SYK, LYN (show LYN Proteins) and PTPN6 (show PTPN6 Proteins) were markedly elevated in atherosclerotic plaques of carotid atherosclerosis patients.

  8. Syk inhibitor suppressed the phosphorylation of band 3 (show SLC4A1 Proteins) also preventing serine phosphorylation changes and hemolysis.

  9. SYK expression was down-regulated in laryngeal squamous cell carcinoma, which was closely correlated with cancer growth and lymph node metastasis. SYK up-regulation was able to inhibit the invasion and metastasis of LSCC.

  10. TNF (show TNF Proteins) activates Mule (show HUWE1 Proteins) by inducing the dissociation of Mule (show HUWE1 Proteins) from its inhibitor ARF. Inhibition of Mule (show HUWE1 Proteins) phosphorylation by silencing Syk prevents this, thereby inhibiting Mule (show HUWE1 Proteins) E3 ligase activity and TNF (show TNF Proteins)-induced JNK (show MAPK8 Proteins) activation and cell death.

Mouse (Murine) Spleen tyrosine Kinase (SYK) interaction partners

  1. Torreya nucifera butanol fraction exhibits anti-inflammatory activities by direct inhibition of macrophage Src (show SRC Proteins)/Syk/NF-kappaB (show NFKB1 Proteins) and IRAK1 (show IRAK1 Proteins)/AP-1 (show JUN Proteins) signaling.

  2. Dectin-1 (show CLEC7A Proteins) and Dectin-2 (show CLEC6A Proteins) seem not to play a major role in Borrelia recognition or Borrelia-induced inflammation. However, Syk seems to be involved in Borrelia-induced cytokine production

  3. TNF (show TNF Proteins) activates Mule by inducing the dissociation of Mule from its inhibitor ARF. Inhibition of Mule phosphorylation by silencing Syk prevents this, thereby inhibiting Mule E3 ligase activity and TNF (show TNF Proteins)-induced JNK (show MAPK8 Proteins) activation and cell death.

  4. The effects of OXSI-2 identified in this study provide context for the role of Syk in inflammasome signaling and demonstrate its importance in oxidative signaling upstream of inflammasome activation and downstream of ion flux.

  5. Mincle (show CLEC4E Proteins) Activation and the Syk/Card9 (show CARD9 Proteins) Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

  6. Syk deletion in myeloid cells is protective in mouse nephrotoxic serum nephritis.

  7. Src (show SRC Proteins)/Syk-dependent signalling stabilises platelet adhesion to podoplanin (show PDPN Proteins)

  8. These results provide new insights into the mechanisms by which SYK regulates MHC-II expression via autophagy in macrophages.

  9. Syk mediates airway contractility in the normal and allergic airways, independent of its role and function in leukocytes, and supports a paracrine role for airway epithelial Syk in modulating airway smooth muscle activity.

  10. Syk expression by DCs is necessary for IL-23p19 (show IL23A Proteins) production in response to C. albicans

Cow (Bovine) Spleen tyrosine Kinase (SYK) interaction partners

  1. These data suggest that Syk mRNA expression dynamics is closely related to bovine leukemia virus-induced disease.

Spleen tyrosine Kinase (SYK) Protein Profile

Protein Summary

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen tyrosine Kinase (SYK)

  • Tyrosine-protein kinase SYK (ksyk)
  • spleen tyrosine kinase (SYK)
  • spleen tyrosine kinase (Syk)
  • p72-Syk protein
  • p72syk protein
  • Sykb protein

Protein level used designations for Spleen tyrosine Kinase Proteins (SYK)

Tyrosine-protein kinase SYK , tyrosine-protein kinase SYK , protein-tyrosine kinase

100380388 Salmo salar
6850 Homo sapiens
20963 Mus musculus
25155 Rattus norvegicus
484196 Canis lupus familiaris
100125540 Sus scrofa
515515 Bos taurus
427272 Gallus gallus
100716985 Cavia porcellus
100345556 Oryctolagus cuniculus
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