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SYK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SYK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733035
  • Target See all SYK Proteins
    SYK (Spleen tyrosine Kinase (SYK))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 7
    • 3
    • 2
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SYK protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SYK (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SYK Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SYK (Spleen tyrosine Kinase (SYK))
    Alternative Name
    Syk (SYK Products)
    Synonyms
    p72-Syk Protein, Sykb Protein, p72syk Protein, spleen associated tyrosine kinase Protein, spleen tyrosine kinase Protein, syk Protein, SYK Protein, Syk Protein
    Background
    This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    71.9 kDa
    NCBI Accession
    NP_003168
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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