Browse our Pancreatic Polypeptide Proteins (PPY)

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Pancreatic Polypeptide Proteins (PPY)
On are 10 Pancreatic Polypeptide (PPY) Proteins from 6 different suppliers available. Additionally we are shipping Pancreatic Polypeptide Antibodies (150) and Pancreatic Polypeptide Kits (52) and many more products for this protein. A total of 243 Pancreatic Polypeptide products are currently listed.
list all proteins Gene Name GeneID UniProt
PPY 5539 P01298
PPY 24677 P06303
PPY 19064 P10601

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Pancreatic Polypeptide Proteins (PPY) by Origin

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More Proteins for Pancreatic Polypeptide Interaction Partners

Human Pancreatic Polypeptide (PPY) interaction partners

  1. GIP (show GIP Proteins) and pancreatic polypeptide plasma concentrations are lower in pancreatic cancer irrespective of the degree of glucose intolerance as compared to Type 2 diabetic patients and healthy controls.

  2. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (show GCG Proteins) release through PPYR1 (show PPYR1 Proteins) receptors expressed by alpha-cells.

  3. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor (show PPYR1 Proteins) binding pocket.

  4. The diagnostic accuracy of the tumor markers CgA (show CGA Proteins), PP, and glucagon (show GCG Proteins) for pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1 is low.

  5. These findings underscore the important role of the NPY (show NPY Proteins)-Y receptor system at several levels of the gut (show GUSB Proteins)-brain axis in which NPY (show NPY Proteins), peptide yy and pancreatic polypeptide operate both as neural and endocrine messengers--{REVIEW}

  6. Pancreatic polypeptide (and peptide tyrosine-tyrosine) increases in obese woman on caloric restriction following high protein liquid meals compared to high carbohydrate liquid meals.

  7. Data suggest that beta-cell function improves in overweight subjects with type 2 diabetes who lose weight by dieting; this change is associated with a decrease in PPY secretion (i.e., plasma PPY is decreased).

  8. Self-association of PPY with phospholipid micelles addressed the delivery issues of the peptide for diabetes treatment.

  9. Women with bulimia nervosa have significantly lower fasting and postprandial serum concentrations of pancreatic polypeptide (and GLP-1 (show GCG Proteins)) than control subjects.

  10. Distribution of pancreatic polypeptide and peptide YY

Mouse (Murine) Pancreatic Polypeptide (PPY) interaction partners

  1. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (show GCG Proteins) release through PPYR1 (show PPYR1 Proteins) receptors expressed by alpha-cells.

  2. PP-initiated signaling through Npy6r in vasoactive intestinal peptide (show Vip PLURAL_@44953@) neurons regulates the growth hormone (show GH1 PLURAL_@44953@) axis and body composition.

  3. investigated the role of metalloendopeptidases in PYY(3-36) degradation and determined whether modulation of these enzymes enhanced PYY(3-36) plasma levels and bioactivity in vivo.

  4. Pancreatic polypeptide enhances colonic contractile activity and fecal output through neuropeptide Y (show NPY Proteins) Y(4) receptor, and a neuropeptide Y (show NPY Proteins) Y(4) receptor agonist might offer a novel therapeutic approach to ameliorate constipation.

  5. Roles of pancreatic polypeptide in regulation of food intake

  6. Pancreatic polypeptide may influence food intake, energy metabolism, and the expression of hypothalamic peptides and gastric ghrelin (show GHRL Proteins).

  7. Increased circulating cholecystokinin (show CCK Proteins) contributes to anorexia and anxiety behavior in mice overexpressing Ppy.

  8. In adult mice, the misexpression of Arx, rather than its overexpression, promotes a conversion of beta cells into glucagon (show GCG Proteins)- or PP-producing cells in vivo.

  9. 67.74% A-cells (glucagon (show GCG Proteins)-secreting cells) had PP (pancreatic polypeptide) immunoreactivity, 70.92% PP-cells contained glucagon (show GCG Proteins) immunoreactivity with immunofluorescence double staining

Pancreatic Polypeptide (PPY) Protein Profile

Protein Summary

This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products\; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Alternative names and synonyms associated with Pancreatic Polypeptide (PPY)

  • pancreatic polypeptide (PPY)
  • pancreatic polypeptide (Ppy)
  • pancreatic polypeptide (LOC100357679)
  • AV061413 protein
  • IGSPP protein
  • PNP protein
  • PP protein
  • PPY protein

Protein level used designations for Pancreatic Polypeptide Proteins (PPY)

pancreatic polypeptide , PP , pancreatic polypeptide Y , pancreatic prohormone , prepro-PP (prepropancreatic polypeptide) , Pancreatic prohormone percursor , panceatic polypeptide , pancreatic hormone , seminalplasmin , Pancreatic prohormone

739802 Pan troglodytes
5539 Homo sapiens
397272 Sus scrofa
280900 Bos taurus
24677 Rattus norvegicus
19064 Mus musculus
490944 Canis lupus familiaris
100357679 Oryctolagus cuniculus
101096772 Felis catus
395564 Gallus gallus
100135605 Cavia porcellus
443280 Ovis aries
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