Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Since the phenotype of the Nias patients differs from the Larsen-like syndrome described for patients with mutation p.(Arg277Gln), we suggest mutation B3GAT3:p.(Pro140Leu) to cause a different type of GAG linkeropathy showing no involvement of the heart.
Reduced GlcAT-I activity impairs skeletal as well as heart development and results in variable combinations of heart malformations.
functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif
we evaluated the consequences of C-4/C-6 sulfation of Galbeta1-3Gal (Gal2 (show GAL2 ELISA Kits)-Gal1 (show LGALS1 ELISA Kits)) on the activity and specificity of beta1,3-glucuronosyltransferase I
GlcAT-I has a role in controlling and reversing articular cartilage defects
A comparison of substrate specificity of beta1,3-glucuronosyltransferases revealed that GlcAT-I was selective toward Galbeta1,3Gal, whereas GlcAT-P (show B3GAT1 ELISA Kits) presented a broader profile.
2-o-phosphorylation of xylose and 6-o-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region synthesis
mice with a deletion of GlcAT-I showed remarkable reduction of the synthesis of chondroitin sulfate and heparan sulfate and embryonic lethality before the 8-cell stage because of failed cytokinesis
The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans.
, UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase
, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
, glucuronosyltransferase I
, glucuronyltransferase I