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anti-Human CD44 Antibodies:
anti-Mouse (Murine) CD44 Antibodies:
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Mouse (Murine) Monoclonal CD44 Primary Antibody for BR, IHC (fro) - ABIN1176866
Hathcock, Hirano, Murakami, Hodes: CD44 expression on activated B cells. Differential capacity for CD44-dependent binding to hyaluronic acid. in Journal of immunology (Baltimore, Md. : 1950) 1994
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody for BR, CyTox - ABIN2689261
Bendelac: Mouse NK1+ T cells. in Current opinion in immunology 1995
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody for FACS - ABIN2689265
Brocke, Piercy, Steinman, Weissman, Veromaa: Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. in Proceedings of the National Academy of Sciences of the United States of America 1999
Show all 21 Pubmed References
Human Polyclonal CD44 Primary Antibody for IHC (p), WB - ABIN3043394
Cui, Qi, Guo, Qin, Gui, Cai: Rat bone marrow derived mesenchymal progenitor cells support mouse ES cell growth and germ-like cell differentiation. in Cell biology international 2009
Show all 17 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody for BR, IHC (f) - ABIN1176842
Castro, Bono, Simon, Vargas, Rosemblatt: Spleen-derived stromal cells. Adhesion molecules expression and lymphocyte adhesion to reticular cells. in European journal of cell biology 1998
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody for BR, IHC (f) - ABIN967622
Godfrey, Kennedy, Suda, Zlotnik: A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. in Journal of immunology (Baltimore, Md. : 1950) 1993
Show all 16 Pubmed References
Mouse (Murine) Monoclonal CD44 Primary Antibody for IHC (f), IHC (fro) - ABIN2689263
Hyman, Lesley, Schulte, Trotter: Progenitor cells in the thymus: most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface. in Cellular immunology 1986
Show all 11 Pubmed References
Human Monoclonal CD44 Primary Antibody for CyTOF, FACS - ABIN4900587
Draffin, McFarlane, Hill, Johnston, Waugh: CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells. in Cancer research 2004
Show all 11 Pubmed References
Human Monoclonal CD44 Primary Antibody for CyTOF, FACS - ABIN4900724
Dingemans, Ramkema, Pals: CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas. in Laboratory investigation; a journal of technical methods and pathology 2002
Show all 10 Pubmed References
Human Monoclonal CD44 Primary Antibody for FACS, ICC - ABIN457426
Si-Tahar, Sitaraman, Shibahara, Madara: Negative regulation of epithelium-neutrophil interactions via activation of CD44. in American journal of physiology. Cell physiology 2001
Show all 8 Pubmed References
Knockdown of CD44 reduced the protein level of xCT (show SLC7A11 Antibodies), a cystine transporter, and increased oxidative stress. However, an increase in GSH was also observed and was associated with enhanced chemoresistance in CD44-knockdown cells. Increased GSH was mediated by the Nrf2 (show GABPA Antibodies)/AP-1 (show FOSB Antibodies)-induced upregulation of GCLC (show GCLC Antibodies), a subunit of the enzyme catalyzing GSH synthesis
CD44 and FGFR2 (show FGFR2 Antibodies) maintain stemness in gastric cancer by differentially regulating c-Myc (show MYC Antibodies) transcription.
Study demonstrated that WNT5A (show WNT5A Antibodies) signaling can suppress CD44 protein expression and signaling. CD44 knockdown reduces the level of pAKT (show AKT1 Antibodies), migration and invasion of breast cancer cell.
MUC1 (show MUC1 Antibodies)-C binds directly with CD44v and in turn promotes stability of xCT (show SLC7A11 Antibodies) in the cell membrane
Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic ductal adenocarcinoma cells.
Together, these data indicate that different mechanisms govern the flow response across GSCs, but that within a single patient, there are subpopulations of GSCs that respond to flow via either CD44- or CXCR4 (show CXCR4 Antibodies)-CXCL12 (show CXCL12 Antibodies) mechanisms.
Our data suggest an important role of beta2-AR/STAT3 (show STAT3 Antibodies)/miR (show MLXIP Antibodies)-373 signaling on the transformation of gastric cancer cells.
High CD44 expression is associated with Malignant Pleural Mesothelioma.
the survival outcomes of genetically induced glioma-bearing mice and of high-grade human glioma patients are biphasically correlated with CD44 level, with the poorest outcomes occurring at intermediate levels.
The rates of CD44st and MMP2 (show MMP2 Antibodies) expression were higher in squamous cell carcinomas than in adenocarcinomas, were closely associated with lymph node metastasis and TNM (show ODZ1 Antibodies) stage, and affected patients' prognoses.
These results suggest that CD44(+)CD117(+) T cells are stem cells and a specific T-cell phenotype that initially develops in the thymus, but they do not progress through DN3 and DN4 stages, lack a DP stage, and potently suppress T-cell proliferation and modulate the CTLA-4 (show CTLA4 Antibodies) pathway.
pERK1/2 is a regulator of CD44 expression, and increased CD44 expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
MET signaling regulates intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10.
study demonstrates that CD44 plays a critical role in the regulation of experimental autoimmune encephalomyelitis through alterations in the gut microbiome profile and short-chain fatty acid production
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
OA/GPNMB acts through ERK (show EPHB2 Antibodies) and AKT (show AKT1 Antibodies) signaling pathways in mesenchymal stem cells via CD44
These findings support the usefulness of the conditional Cd44 allele in unraveling essential physiological and pathological functions of CD44 isoforms.
CD44 role in the atrophic epidermis
CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (show CD14 Antibodies)-negative isolation yields an enhanced cell population SFB (show CEBPB Antibodies) that is more potent than MSCP (show SLC25A37 Antibodies) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Antibodies).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Antibodies), CD44, and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR Antibodies)-mediated signalling pathways involving Cdc2 (show CDK1 Antibodies) and gamma-adducin (show ADD3 Antibodies).
The novel finding that TSP-1 (show THBS1 Antibodies)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 Antibodies) and HyA (show KDM5D Antibodies)).
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, extracellular matrix receptor III
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, hyaluronate receptor
, phagocytic glycoprotein 1
, hermes antigen
, lymphocyte antigen 24
, phagocytic glycoprotein I
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, CD44-like protein
, extracellular matrix receptor-III
, lymphocyte surface antigen precursor CD44
, CD44 molecule (Indian blood group) S homeolog
, hyaluronan receptor CD44