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Mouse (Murine) CD44 ELISA Kit for Sandwich ELISA - ABIN457122
Campo, Avenoso, DAscola, Prestipino, Scuruchi, Nastasi, Calatroni, Campo: Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. in Archives of biochemistry and biophysics 2012
Show all 5 Pubmed References
Human CD44 ELISA Kit for Sandwich ELISA - ABIN2859264
Li, Chu, Gao, Li: Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin. in Acta biochimica et biophysica Sinica 2009
pERK1/2 is a regulator of CD44 expression, and increased CD44 expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
MET signaling regulates intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10.
study demonstrates that CD44 plays a critical role in the regulation of experimental autoimmune encephalomyelitis through alterations in the gut microbiome profile and short-chain fatty acid production
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
OA/GPNMB acts through ERK (show EPHB2 ELISA Kits) and AKT (show AKT1 ELISA Kits) signaling pathways in mesenchymal stem cells via CD44
These findings support the usefulness of the conditional Cd44 allele in unraveling essential physiological and pathological functions of CD44 isoforms.
CD44 role in the atrophic epidermis
CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.
CD44V6 is part of a positive-feedback loop with TGFbeta1 (show TGFB1 ELISA Kits)/TGFbetaRI signaling that acts to increase NOX4 (show NOX4 ELISA Kits)/ROS (show ROS1 ELISA Kits) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.
HAS2 (show HAS2 ELISA Kits)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (show MAPK3 ELISA Kits)/EGR1 (show EGR1 ELISA Kits) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (show TGFB1 ELISA Kits)-stimulated CD44V6/ERK (show EPHB2 ELISA Kits)/EGR1 (show EGR1 ELISA Kits) signaling.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (show CD14 ELISA Kits)-negative isolation yields an enhanced cell population SFB (show CEBPB ELISA Kits) that is more potent than MSCP (show SLC25A37 ELISA Kits) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
suggest that upregulation of NG2/CSPG4 (show MCSP ELISA Kits) rather than changes in CD44 or Ki-67 (show MKI67 ELISA Kits) expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 (show MCSP ELISA Kits) as a potential prognostic marker in glioblastoma
Suggest that CD44-positivity might be a candidate tumor stem cell marker in intrahepatic cholangiocarcinoma and a prognostic indicator.
Mechanistically, CD44v interacts with and stabilizes xCT (show SLC7A11 ELISA Kits) and thereby promotes the uptake of cysteine for glutathione synthesis and stimulates side-population cell enrichment.
These tumor samples express CD44 protein at low rather than high levels. There is no correlation between CLDN3 (show CLDN3 ELISA Kits) gene expression and protein expression in these CPTAC samples; hence, the claudin-low subtype defined by gene expression is not the same group of tumors as that defined by low expression of CLDN3 (show CLDN3 ELISA Kits) protein.
this study shows that genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1 (show PKD1 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) signaling pathway
High CD44 expression is associated with high grade glioma.
CNS disease was associated with enhanced expression of cytoplasmic and membranous ITGA10 and nuclear PTEN (P < 0.0005, P = 0.002, P = 0.024, respectively). sCNSL presented decreased membranous CD44 and nuclear and cytoplasmic cadherin-11 expressions (P = 0.001, P = 0.006, P = 0.048, respectively). In PCNSL lactoferrin (show LTF ELISA Kits) expression was upregulated (P < 0.0005).
In clinical specimens of breast cancer, authors established that the expression of CD44s and HAS2 (show HAS2 ELISA Kits) was positively correlated. Results establish a positive feedback mechanism that sustains PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling in tumor cells, further illuminating the nearly universal role of this pathway in cancer cell survival.
In regulation of tumour cells with high CD44 expression.
ZEB1 (show ZEB1 ELISA Kits)-induced epithelial-to-mesenchymal transition and associated molecular changes in ESRP1 (show ESRP1 ELISA Kits) and CD44 contribute to early pathogenesis and metastatic potential in established lung cancer
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 ELISA Kits).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA ELISA Kits), CD44, and CD62L (show SELL ELISA Kits) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR ELISA Kits)-mediated signalling pathways involving Cdc2 (show CDK1 ELISA Kits) and gamma-adducin (show ADD3 ELISA Kits).
The novel finding that TSP-1 (show THBS1 ELISA Kits)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 ELISA Kits) and HyA (show KDM5D ELISA Kits)).
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, extracellular matrix receptor III
, hermes antigen
, hyaluronate receptor
, lymphocyte antigen 24
, phagocytic glycoprotein 1
, phagocytic glycoprotein I
, CD44 antigen
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, extracellular matrix receptor-III
, CD44-like protein
, lymphocyte surface antigen precursor CD44
, syndecan 4 (amphiglycan, ryudocan)