Browse our Fucosidase, alpha-L- 1, Tissue Proteins (FUCA1)

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Fucosidase, alpha-L- 1, Tissue Proteins (FUCA1)
On are 15 Fucosidase, alpha-L- 1, Tissue (FUCA1) Proteins from 7 different suppliers available. Additionally we are shipping Fucosidase, alpha-L- 1, Tissue Antibodies (86) and Fucosidase, alpha-L- 1, Tissue Kits (34) and many more products for this protein. A total of 143 Fucosidase, alpha-L- 1, Tissue products are currently listed.
0610006A03Rik, 9530055J05Rik, Afuc, alpha-L-fucosidase 1, ATFUC1, F24D13.11, F24D13_11, Fuca, fuca1, wu:fj17c05
list all proteins Gene Name GeneID UniProt
FUCA1 2517 P04066
FUCA1 71665 Q99LJ1
FUCA1 24375 P17164

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Fucosidase, alpha-L- 1, Tissue Proteins (FUCA1) by Origin

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More Proteins for Fucosidase, alpha-L- 1, Tissue Interaction Partners

Human Fucosidase, alpha-L- 1, Tissue (FUCA1) interaction partners

  1. RNAi-mediated knockdown of endogenous FUCA1 significantly attenuates p53 (show TP53 Proteins)-dependent, chemotherapy-induced apoptotic death.

  2. whole exome sequencing and array-based comparative genomic hybridization analysis revealed that the patient was compound heterozygous for a single base-pair deletion inherited from his father, and a 3281-base-pair deletion covering exon 3 inherited from his mother. Neither mutation has been reported before so the FUCA1 mutational spectrum is herein expanded.

  3. results show that protein defucosylation mediated by FUCA1 is involved in tumor suppression

  4. FUCA1 downregulation confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

  5. We observed significant lower values of GAL (show GAL Proteins), alpha-fucosidase and tendency to decrease of MAN and GLU (show DCTN1 Proteins) concentration in nasal polyps

  6. Serum alpha-L-fucosidase levels were significantly elevated in hepatocellular carcinoma.

  7. IL-13 (show IL13 Proteins), IL-4 (show IL4 Proteins) and IL-5 (show IL5 Proteins) have no effect on the expression of FUCA1 and FUCA2 (show FUCA2 Proteins), but its expression is upregulated by IFN-gamma (show IFNG Proteins), a Th1 (show TH1L Proteins) cytokine.

  8. Diminished FUCA1 mRNA levels in tumors, indicate that expression of tissue alpha-L-fucosidase could be regulated at transcriptional level in colorectal cancer.

  9. In the serum of patients with Lyme disease, GAL (show GAL Proteins) activity significantly increased (p = 0.029), and the activity of FUC had a tendency to increase (p = 0.153), compared to the control group.

  10. The purified alpha-L-fucosidase from primary hepatocarcinoma (PHC (show SLC25A3 Proteins)) is different in its properties from alpha-L-fucosidase in human other organs. The polyclonal antibody prepared in this experiment can be applied to the diagnosis of PHC (show SLC25A3 Proteins).

Fucosidase, alpha-L- 1, Tissue (FUCA1) Protein Profile

Protein Summary

The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.

Alternative names and synonyms associated with Fucosidase, alpha-L- 1, Tissue (FUCA1)

  • fucosidase, alpha-L- 1, tissue (fuca1)
  • fucosidase, alpha-L- 1, tissue (FUCA1)
  • alpha-L-fucosidase 1 (ATFUC1)
  • alpha-L-fucosidase 1 (LOC100285202)
  • alpha-L-fucosidase 1 (FUC1)
  • fucosidase, alpha-L- 1, tissue (fuca1-b)
  • fucosidase, alpha-L- 1, tissue (Fuca1)
  • 0610006A03Rik protein
  • 9530055J05Rik protein
  • Afuc protein
  • alpha-L-fucosidase 1 protein
  • ATFUC1 protein
  • F24D13.11 protein
  • F24D13_11 protein
  • Fuca protein
  • fuca1 protein
  • wu:fj17c05 protein

Protein level used designations for FUCA1

fucosidase, alpha-L-1, tissue , tissue alpha-L-fucosidase , fucosidase, alpha-L- 1, tissue , alpha-L-fucosidase 1 , tissue alpha-L-fucosidase-like , alpha-L-fucosidase I , alpha-L-fucoside fucohydrolase 1 , Fucosidase alpha-L-1 tissue , Fucosidase, alpha-L-1, tissue

335494 Danio rerio
469222 Pan troglodytes
710993 Macaca mulatta
100071543 Equus caballus
548577 Xenopus (Silurana) tropicalis
9317020 Arabidopsis lyrata subsp. lyrata
100285202 Zea mays
100386419 Callithrix jacchus
817355 Arabidopsis thaliana
432087 Xenopus laevis
2517 Homo sapiens
403929 Canis lupus familiaris
509522 Bos taurus
71665 Mus musculus
24375 Rattus norvegicus
100357404 Oryctolagus cuniculus
100721805 Cavia porcellus
419687 Gallus gallus
101119449 Ovis aries
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