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Human Polyclonal NDST4 Primary Antibody for WB - ABIN2783876
Aikawa, Grobe, Tsujimoto, Esko: Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. in The Journal of biological chemistry 2001
The rs12108602 near NDST4 showed significant associations with MaxDrinks.
NDST4 gene is a novel candidate tumor suppressor gene in human cancer.
Our results suggest that genetic variants in TYW3 (show TYW3 Antibodies)/CRYZ (show CRYZ Antibodies) and NDST4 loci may be involved in the regulation of circulating resistin (show RETN Antibodies) levels
Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity.
, N-heparan sulfate sulfotransferase 4
, bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
, glucosaminyl N-deacetylase/N-sulfotransferase 4
, N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
, N-deacetylase/N-sulfotransferase 4