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Browse our anti-Sonic Hedgehog (SHH) Antibodies

Full name:
anti-Sonic Hedgehog Antibodies (SHH)
On www.antibodies-online.com are 128 Sonic Hedgehog (SHH) Antibodies from 25 different suppliers available. Additionally we are shipping Sonic Hedgehog Proteins (88) and Sonic Hedgehog Kits (23) and many more products for this protein. A total of 248 Sonic Hedgehog products are currently listed.
Synonyms:
9530036O11Rik, Dsh, fc83d08, hedgehog, HHG1, HLP3, HPE3, Hx, Hxl3, M100081, MCOPCB5, SHH, SMMCI, syu, TPT, TPTPS, vhh-1, vhh1, wu:fc83d08, Xhh, xshh

Most Popular Reactivities for anti-Sonic Hedgehog (SHH) Antibodies

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anti-Mouse (Murine) Sonic Hedgehog Antibodies:

anti-Human Sonic Hedgehog Antibodies:

anti-Rat (Rattus) Sonic Hedgehog Antibodies:

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Top referenced anti-Sonic Hedgehog Antibodies

  1. Human Monoclonal Sonic Hedgehog Primary Antibody for ELISA - ABIN393243 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Show all 5 references for ABIN393243

  2. Human Polyclonal Sonic Hedgehog Primary Antibody for IF (p), IHC (p) - ABIN731108 : Weiss, Guo, Shan, Shi, Romano, Sinha, Cantley, Guo: Brg1 determines urothelial cell fate during ureter development. in Journal of the American Society of Nephrology : JASN 2013 (PubMed)
    Show all 5 references for ABIN731108

  3. Human Monoclonal Sonic Hedgehog Primary Antibody for ELISA, WB - ABIN969395 : Dierker, Dreier, Migone, Hamer, Grobe: Heparan sulfate and transglutaminase activity are required for the formation of covalently cross-linked hedgehog oligomers. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN969395

  4. Human Monoclonal Sonic Hedgehog Primary Antibody for FACS, IHC - ABIN969567 : Kameda, Nakamura, Tanaka, Yamasaki, Kubo, Tanaka, Onishi, Katano: Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer. in British journal of cancer 2010 (PubMed)

  5. Chicken Polyclonal Sonic Hedgehog Primary Antibody for IHC, WB - ABIN2781775 : Coon, Roberts, Loscertales, Kradin: Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia. in Experimental and molecular pathology 2006 (PubMed)

More Antibodies against Sonic Hedgehog Interaction Partners

Mouse (Murine) Sonic Hedgehog (SHH) interaction partners

  1. When the Shh signaling inhibitor jervine was added to the culture medium for 24-96 h, the formation of lateral lingual swellings and subsequent epithelial invagination into the mesenchyme were impaired markedly, leading to a hypoplastic tongue

  2. Report exposes a novel role for Shh in regulating mitochondrial dynamics and rescue the metabolic profile of tumor cells through regulation of mitofusin 1 (show MFN1 Antibodies) and 2.

  3. The effect of fibronectin (show FN1 Antibodies) on the neurite outgrowth from embryoid bodies in neurodifferentiated embryonal carcinoma P19 (show CDKN2D Antibodies) cells was studied.

  4. Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis. Hedgehog's effects on apoptosis can occur independent of glucocorticoid stimulation.

  5. We proposed that LKB1 (show STK11 Antibodies) regulates cerebellar development by controlling GCPs proliferation through Shh signalling during cerebellar development.

  6. Data show that the proliferation of sustained expression of Notch1 (show NOTCH1 Antibodies)-induced choroid plexus (CP) tumours relies on Sonic Hedgehog (Shh) from the tumour microenvironment through their primary cilium.

  7. NANOG (show NANOG Antibodies) binds to GLI1 (show GLI1 Antibodies) and GLI3 (show GLI3 Antibodies) proteins and represses Hedgehog-mediated transcription.

  8. Specific inactivation of Srg3 (show SMARCC1 Antibodies) a core subunit of the remodeling complex, in developing limb buds hampered the transcriptional upregulation of Shh/Gli (show GLI1 Antibodies) target genes, including the Shh receptor Ptch1 (show PTCH1 Antibodies) and its downstream effector Gli1 (show GLI1 Antibodies) in the posterior limb bud

  9. Loss of N-myc (show MYCN Antibodies) significantly impairs the Sonic hedgehog signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (show CCND2 Antibodies).

  10. Results suggest that amygdala neurogenesis and Shh signaling are involved in the extinction of fear memory

Human Sonic Hedgehog (SHH) interaction partners

  1. MAPK (show MAPK1 Antibodies) and SHH pathways modulate type 3 deiodinase (show DIO3 Antibodies) expression in papillary thyroid carcinoma

  2. during human brain development, Shh plays an important role in the specification of cortical progenitors

  3. The disruption of a novel limb cis (show CISH Antibodies)-regulatory element of SHH is associated with autosomal dominant preaxial polydactyly-hypertrichosis in a large French pedigree.

  4. Results obtained from in vitro and in vivo studies demonstrate that Shh may function as an inducer of bladder cancer progression. Its expression correlates with advanced clinical stages and poor prognostic bladder cancer.

  5. The sonic hedgehog protein, through its receptors, plays a role in embryo development, in idiopathic pulmonary fibrosis, and in small cell lung carcinoma, non-small cell lung carcinoma and malignant pleural mesothelioma. Review.

  6. Crocetinic acid inhibited the expression of both Shh and smoothened (show SMO Antibodies) in pancreatic cancer stem cells, thereby inhibiting pancreatic tumorigenesis

  7. hyperactivity of Hh signaling resulted in EGFR (show EGFR Antibodies)-TKI resistance, by EMT (show ITK Antibodies) introduction and ABCG2 (show ABCG2 Antibodies) upregulation, and blockade of Hh signaling synergistically increased sensitivity to EGFR (show EGFR Antibodies)-TKIs in primary and secondary resistant NSCLC cells

  8. Increased SHH, PTCH (show PTCH1 Antibodies), and GLI1 (show GLI1 Antibodies) protein correlated positively with tumor grade, tumor depth and lymph node metastasis in Peutz-Jeghers syndrome.

  9. Data suggest that substrate specificity of hedgehog acyltransferase (HHAT (show HHAT Antibodies)) in palmitoylation reaction extends to oligopeptide fragments of Sonic hedgehog protein (SHH).

  10. Data indicate that regulation of sonic hedgehog (SHh)-GLI family zinc finger 1 (Gli1 (show GLI1 Antibodies)) signals to migration of pancreatic cancer AsPC-1 Cells through mediating eukaryotic translation initiation factor 5A (EIF5A2 (show EIF5A2 Antibodies)) gene expression.

Xenopus laevis Sonic Hedgehog (SHH) interaction partners

  1. Data indicate that sonic hedgehog is expressed exclusively in the notochord but not in the spinal cord of the regenerate.

  2. Dzip1 (show DZIP1 Antibodies)-dependent stabilization of Spop (show SPOP Antibodies)/HIB is evolutionarily conserved and essential for proper regulation of Gli (show GLI1 Antibodies)/Ci proteins in the Hh pathway.

  3. Notch (show NOTCH1 Antibodies) signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh expression in the midline.

  4. These results indicate that electrical activity and second-messenger signaling mediate Shh action in embryonic spinal neurons.

  5. Connective tissue-specific expression of BMP-4 (show BMP4 Antibodies) mRNA is up-regulated by sonic hedgehog.

  6. In an examination of signaling pathways in developing Xenopus lung, shh but not ihh (show IHH Antibodies) was expressed in the very anterior part of early lung epithelium.

  7. Data propose that Shh serves as a ventral optic tract repellent that helps to define the caudal (show CAD Antibodies) boundary for retinal axons in the diencephalon, and that this signaling is also required for initial target recognition at the optic tectum.

  8. The forebrain of Xenopus revealed a largely conserved pattern of Shh expression among tetrapods.

  9. Hedgehog regulates superficial slow muscle fibres in Xenopus and tetrapod trunk myogenesis

  10. Results suggest that 7-dehydrocholesterol reductase (show DHCR7 Antibodies) and Sonic Hedgehog are co-expressed during midline development in Xenopus embryos

Cow (Bovine) Sonic Hedgehog (SHH) interaction partners

  1. study shows evolutionary alteration of a Ptch1 (show PTCH1 Antibodies) cis (show CISH Antibodies)-regulatory module, which no longer responds to graded SHH signalling during bovine handplate development

Zebrafish Sonic Hedgehog (SHH) interaction partners

  1. Opposing Shh and Fgf signals initiate nasotemporal patterning of the zebrafish retina.

  2. Hedgehog signaling has a role in dental papilla formation and tooth size during zebrafish odontogenesis

  3. Data indicate that the transgenic lines report Hedgehog pathway state in individual cells and with high sensitivity.

  4. We further demonstrate that the elevated Hedgehog signaling in Sox11 (show SOX11 Antibodies)-deficient zebrafish was caused by a large increase in shha transcription; indeed, suppressing Shha expression rescued the ocular phenotypes of sox11 (show SOX11 Antibodies) morphants.

  5. Pax6 (show PAX6 Antibodies) has an evolutionarily conserved function in establishing the temporospatial expression of Shh in the mid-diencephalic organizer in vertebrates.

  6. Sulf1 (show SULF1 Antibodies) triggers Shh signaling activity to establish and, later on, modify the spatial arrangement of gene expression in ventral neural progenitors

  7. These studies provide evidence that a signaling pathway involving agrin (show AGRN Antibodies), Fgfs and Shh may be a critical target of ethanol exposure during zebrafish embryogenesis.

  8. heterozygote mutations in fgf8 (show FGF8 Antibodies), shh or oep (show TDGF1 Antibodies) lead to a reduced number of ascending dopaminergic neurons in zebrafish and may confer increased susceptibility to the Parkinson disease

  9. Hh is able to bypass VEGF to induce arterial differentiation in ECs via the calcitonin receptor-like receptor, thus revealing a surprising complexity in the interplay between Hh and VEGF signaling during arteriovenous specification.

  10. The Sphingosine-1-phospate-dependent anterior foregut endoderm functions primarily through Shh to regulate the growth but not dorsoventral patterning of zebrafish jaw precursors.

Sonic Hedgehog (SHH) Antigen Profile

Antigen Summary

This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly.

Alternative names and synonyms associated with Sonic Hedgehog (SHH)

  • sonic hedgehog (shh) antibody
  • sonic hedgehog (SHH) antibody
  • sonic hedgehog (LOC100352774) antibody
  • sonic hedgehog (Shh) antibody
  • sonic hedgehog a (shha) antibody
  • 9530036O11Rik antibody
  • Dsh antibody
  • fc83d08 antibody
  • hedgehog antibody
  • HHG1 antibody
  • HLP3 antibody
  • HPE3 antibody
  • Hx antibody
  • Hxl3 antibody
  • M100081 antibody
  • MCOPCB5 antibody
  • SHH antibody
  • SMMCI antibody
  • syu antibody
  • TPT antibody
  • TPTPS antibody
  • vhh-1 antibody
  • vhh1 antibody
  • wu:fc83d08 antibody
  • Xhh antibody
  • xshh antibody

Protein level used designations for anti-Sonic Hedgehog (SHH) Antibodies

sonic hedgehog protein , sonic hedgehog , HHG-1 , hemimelic extra toes , short digits , sonic hedgehog homolog , VHH-1 , X-SHH , morphogen , sonic hedgehog protein A , sonic-you

GENE ID SPECIES
446055 Takifugu rubripes
100049186 Oryzias latipes
100136227 Oncorhynchus mykiss
100169727 Felis catus
100352774 Oryctolagus cuniculus
100505407 Sus scrofa
20423 Mus musculus
6469 Homo sapiens
398047 Xenopus laevis
395615 Gallus gallus
608860 Canis lupus familiaris
29499 Rattus norvegicus
286821 Bos taurus
30269 Danio rerio
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