Browse our LDLR (LDLR) ELISA Kits

Full name:
Low Density Lipoprotein Receptor ELISA Kits (LDLR)
On www.antibodies-online.com are 50 Low Density Lipoprotein Receptor (LDLR) ELISA Kits from 16 different suppliers available. Additionally we are shipping LDLR Antibodies (281) and LDLR Proteins (39) and many more products for this protein. A total of 378 LDLR products are currently listed.
Synonyms:
FH, FHC, Hlb301, LDLA, LDLCQ2, LDLRA

More ELISA Kits for LDLR Interaction Partners

Human Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. PCSK9 (show PCSK9 ELISA Kits) inhibits lipoprotein(a) clearance through the LDLR.

  2. 4 siblings found to be compound heterozygotes for 2 LDLR gene mutations but showing a different phenotype severity

  3. LDLR is a relevant receptor for CNS drug delivery via receptor-mediated transcytosis and that the peptide vectors we developed have the potential to transport drugs

  4. Higher Gleason grade was associated with lower LDLR expression, lower SOAT1 (show SOAT1 ELISA Kits) and higher SQLE (show SQLE ELISA Kits) expression. Besides high SQLE (show SQLE ELISA Kits) expression, cancers that became lethal despite primary treatment were characterized by low LDLR expression (odds ratio for highest versus lowest quintile, 0.37; 95% CI 0.18-0.76) and by low SOAT1 (show SOAT1 ELISA Kits) expression (odds ratio, 0.41; 95% CI 0.21-0.83).

  5. LDLR associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age /=160 mg/dl.

  6. Chinese W483X mutation in the low-density lipoprotein-receptor gene in young patients with homozygous familial hypercholesterolemia

  7. Proprotein convertase subtilisin (show PCSK9 ELISA Kits)/kexin 9 V4I variant with LDLR mutations modifies the phenotype of familial hypercholesterolemia

  8. both LDLR rs6511720 and rs57217136 are functional variants; both these minor alleles create enhancer-binding protein sites for transcription factors and may contribute to increased LDLR expression, which is consequently associated with reduced LDL-C levels and 12% lower coronary heart disease risk

  9. Using assays that measured conformational change, acid-dependent lipoprotein release, LDLR recycling, and net lipoprotein uptake, we show that H635 plays important roles in acid-dependent conformational change and lipoprotein release, while H264, H306, and H439 play ancillary roles in the response of the LDLR to acidic pH

  10. these studies support that reductions in Lp(a (show APOA ELISA Kits)) with PCSK9 (show PCSK9 ELISA Kits) inhibition are partly due to increased LDLR-mediated uptake. In most situations, Lp(a (show APOA ELISA Kits)) appears to compete poorly with LDL for LDLR binding and internalization, but when LDLR expression is increased with evolocumab, particularly in the setting of low circulating LDL, Lp(a (show APOA ELISA Kits)) is reduced.

Cow (Bovine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB ELISA Kits), ApoE (show APOE ELISA Kits), MTP (show MTTP ELISA Kits), and LDLR, thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

Mouse (Murine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. PCSK9 (show PCSK9 ELISA Kits) inhibits lipoprotein(a) clearance through the LDLR.

  2. PTP1B (show PTPN1 ELISA Kits) inhibitors protect against atherosclerotic plaque formation in the LDLR(-/-) mouse model of atherosclerosis.

  3. LDLR is a relevant receptor for CNS drug delivery via receptor-mediated transcytosis and that the peptide vectors we developed have the potential to transport drugs

  4. ApoC-III (show APOC3 ELISA Kits) inhibits turnover of TG-rich lipoproteins primarily through a hepatic clearance mechanism mediated by the LDLR/LRP1 (show LRP1 ELISA Kits) axis

  5. Leukocyte GPR120/FFAR4 (show O3FAR1 ELISA Kits) WT or KO mice in the LDL receptor KO background were generated by bone marrow transplantation.leukocyte GPR120 (show O3FAR1 ELISA Kits) expression has minimal effects on dietary PUFA-induced plasma lipid/lipoprotein reduction and atheroprotection, and there is no distinction between n-3 versus n-6 PUFAs in activating anti-inflammatory effects of leukocyte GPR120/FFAR4 (show O3FAR1 ELISA Kits) in vivo

  6. This study reports the creation of a mouse model of autoimmunity-associated atherosclerosis by transplanting bone marrow from FcgammaRIIB knockout (FcRIIB(-/-)) mice into LDL receptor knockout mice.

  7. hepatocytes clear lipopolysaccharides from the circulation via the LDLR.

  8. Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor

  9. Cyclosporin A does not cause hyperlipidemia via direct effects on the LDLr. Rather, LDLr deficiency plays an important permissive role for CsA (show HSPA9 ELISA Kits)-induced hyperlipidemia, which is associated with abnormal lipoprotein clearance, decreased lipoprotein lipase (show LPL ELISA Kits) activity, and increased levels of apolipoprotein C-III (show APOC3 ELISA Kits) and proprotein convertase subtilisin/kexin type 9 (show PCSK9 ELISA Kits).

  10. Ldlr(-/-) Creb3l3 (show CREB3L3 ELISA Kits)(-/-) mice developed significantly more atherosclerotic lesions in the aortas than Ldlr(-/-) mice.

Pig (Porcine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. The LDLR gene should be a candidate causative gene for LDL-cholesterol and total cholesterol in pigs, but heterogeneity exists in different populations.

  2. KLF13 (show KLF13 ELISA Kits) and SREBP-Sp1 (show SP1 ELISA Kits) activation interact to regulate low density lipoprotein receptor promoter function

  3. found association between genotypes for LDLR and APOB (show APOB ELISA Kits) polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

LDLR Antigen Profile

Antigen Summary

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with LDLR

  • low density lipoprotein receptor (ldlr) Elisa Kit
  • low density lipoprotein receptor (LDLR) Elisa Kit
  • low density lipoprotein receptor (Ldlr) Elisa Kit
  • low density protein receptor (LOC443535) Elisa Kit
  • FH Elisa Kit
  • FHC Elisa Kit
  • Hlb301 Elisa Kit
  • LDLA Elisa Kit
  • LDLCQ2 Elisa Kit
  • LDLRA Elisa Kit

Protein level used designations for LDLR

low-density lipoprotein receptor , LDL receptor , low-density lipoprotein receptor class A domain-containing protein 3 , low density lipoprotein receptor (familial hypercholesterolemia)

GENE ID SPECIES
387529 Danio rerio
3949 Homo sapiens
281276 Bos taurus
100009086 Oryctolagus cuniculus
16835 Mus musculus
300438 Rattus norvegicus
100724238 Cavia porcellus
396801 Sus scrofa
100683160 Canis lupus familiaris
395103 Gallus gallus
100689399 Cricetulus griseus
443535 Ovis aries
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