Browse our anti-FNDC5 (FNDC5) Antibodies

Full name:
anti-Fibronectin Type III Domain Containing 5 Antibodies (FNDC5)
On are 62 Fibronectin Type III Domain Containing 5 (FNDC5) Antibodies from 12 different suppliers available. Additionally we are shipping FNDC5 Kits (70) and FNDC5 Proteins (28) and many more products for this protein. A total of 174 FNDC5 products are currently listed.
1500001L03Rik, AI836596, C87088, fndc5, FRCP2, irisin, PeP, Pxp, si:dkey-264p5.1, zgc:158684

Most Popular Reactivities for anti-FNDC5 (FNDC5) Antibodies

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anti-Human FNDC5 Antibodies:

anti-Mouse (Murine) FNDC5 Antibodies:

anti-Rat (Rattus) FNDC5 Antibodies:

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Top referenced anti-FNDC5 Antibodies

  1. Human Polyclonal FNDC5 Primary Antibody for FACS, IF (p) - ABIN1387505 : Park, Kim, Choi, Heo, Park: New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. in Cellular signalling 2015 (PubMed)

  2. Human Polyclonal FNDC5 Primary Antibody for WB - ABIN1169430 : Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. in Cell metabolism 2013 (PubMed)

  3. Human Polyclonal FNDC5 Primary Antibody for IHC, IHC (p) - ABIN4327646 : Komolka, Albrecht, Schering, Brenmoehl, Hoeflich, Maak: Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? in PLoS ONE 2014 (PubMed)

More Antibodies against FNDC5 Interaction Partners

Cow (Bovine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Neither FNDC5 nor its putatively secreted peptide irisin were found in circulation of bulls.

Human Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Plasma irisin modestly increases during moderate and high-intensity afternoon exercise in obese females.

  2. correlation between irisin and adiposity related factors suggests that that in the case of this clinical model, irisin is regulated by adiposity and not by GH

  3. Collectively, our study identified serum irisin as a predictive biomarker for 1-year all-cause mortality in acute heart failure patients though large multicenter studies are highly needed.

  4. T2DM and diabetic nephropathy are associated with decreased levels of irisin. FNDC5 rs16835198 TT genotype associates with decreased risk of T2DM in Egyptians with no effect on renal complications. Also, G allele has insulin (show INS Antibodies) desensitizing action with no association with circulating irisin levels.

  5. irisin might serve as a possible signal for linking body fat/muscle mass with the hypothalamic center governing reproductive function

  6. Results indicate that cytokines might predict irisin concentration in mothers and their offspring.

  7. These findings suggest that IL-17A (show IL17A Antibodies) is an independent risk factor of non-proliferative diabetic retinopathy, and irisin could protect against diabetic retinopathy through potential anti-IL-17A (show IL17A Antibodies) effects.

  8. All results indicated that irisin has protective effect on LPS (show IRF6 Antibodies)-induced ALI in mice and in A549 cells. Thus, irisn related with physical exercise may be a potential therapy for the treatment of pulmonary inflammation.

  9. In the first trimester, irisin levels were significantly lower in women who later developed GDM (median = 453 ng/mL, range: 257-811 ng/mL) than in controls (median = 721 ng/mL, range: 700-786 ng/mL). In the second trimester, the difference in irisin levels between the GDM group (median = 749 ng/mL; range: 456-910 ng/mL) and controls (median = 757 ng/mL; range: 703-898 ng/mL) was not statistically significant.

  10. increased irisin levels might contribute to altered energy metabolism in hyperthyroidism

Mouse (Murine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Irisin improved endothelial function by modulating HO-1 (show HMOX1 Antibodies)/ adiponectin (show ADIPOQ Antibodies) axis in perivascular adipose tissue (PVAT) in HFD-induced obese mice. These findings suggest that regulating PVAT function may be a potential mechanism by which irisin improves endothelial function in obesity.

  2. results are the first to demonstrate that the protective effects of irisin in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (show HDAC5 Antibodies) degradation.

  3. The results indicate that FNDC5 deficiency impairs autophagy and FAO and enhances lipogenesis via the AMPK (show PRKAA1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway. FNDC5 deficiency aggravates whereas FNDC5 overexpression prevents the HFD-induced hyperlipemia, hepatic lipid accumulation, and impaired FAO and autophagy in the liver.

  4. This research is the first to show that irisin modulates macrophage activity by reducing reactive oxygen species (ROS (show ROS1 Antibodies)) overproduction, which could suggest its potential anti-inflammatory properties.

  5. No FNDC5 expression was detected in normal or cancerous stomach tissues. FNDC5 expression in white and brown adipose tissues in the cancer group increased compared with the control and non-cancer groups.

  6. Report showed that irisin suppressed cholesterol synthesis in hepatocytes through the activation of 5' AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) and subsequent inhibition of transcription and nuclear translocation of SREBP2 (show SREBF2 Antibodies).

  7. PGC1alpha regulates FNDC5 and its processed and secreted peptide Irisin, which has been proposed to play a critical role in energy expenditure and to promote neural differentiation of mouse embryonic stem cells. Review.

  8. it is concluding that an enhanced expression of Fndc5 in neural progenitor cells is stimulated by Zfp521 (show ZNF521 Antibodies) overexpression in these cells

  9. Irisin directly targets osteoblast, promoting osteoblast proliferation and differentiation via activating P38/ERK MAP kinase (show MAPK1 Antibodies) signaling cascades in vitro.

  10. irisin does not function through inflammatory NFKB activation like other myokines (such as TNFalpha (show TNF Antibodies)).

FNDC5 Antigen Profile

Antigen Summary

mouse homolog is linked to myoblast differentiation and development

Alternative names and synonyms associated with FNDC5

  • fibronectin type III domain containing 5 (FNDC5) antibody
  • fibronectin type III domain containing 5 (Fndc5) antibody
  • fibronectin type III domain containing 5b (fndc5b) antibody
  • 1500001L03Rik antibody
  • AI836596 antibody
  • C87088 antibody
  • fndc5 antibody
  • FRCP2 antibody
  • irisin antibody
  • PeP antibody
  • Pxp antibody
  • si:dkey-264p5.1 antibody
  • zgc:158684 antibody

Protein level used designations for FNDC5

fibronectin type III domain-containing protein 5 , fibronectin type III domain containing 5 , fibronectin type III repeat-containing protein 2 , peroxisomal protein

419667 Gallus gallus
487302 Canis lupus familiaris
538905 Bos taurus
746970 Pan troglodytes
252995 Homo sapiens
384061 Mus musculus
260327 Rattus norvegicus
100726842 Cavia porcellus
101104971 Ovis aries
555635 Danio rerio
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