Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human Aquaporin 1 Protein expressed in Wheat germ - ABIN1345420
Marusalin, Matier, Rheault, Donini: Aquaporin homologs and water transport in the anal papillae of the larval mosquito, Aedes aegypti. in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 2012
In situ hybridization and immunohistochemistry showed that the AQP1a.1 transcript was highly expressed by acid-secreting ionocytes.
endogenous aqp1a expression was observed in both primitive and definitive hematopoietic erythroid progenitors, in the otic vesicle, swim bladder, pneumatic duct, intestine and a subset of neurons within the retina and the midbrain-hindbrain region.
Compared with human AQP1, zebrafish Aqp1a has about twice the selectivity for CO(2) over NH(3).
AQP0 modulates GJs in the presence of BF proteins to maintain lens transparency and homeostasis.
Our results demonstrate that Aqp1 is maternally expressed in the placenta, and that its deficiency resulted in placental abnormalities in the mouse. Aqp1 may have a specific inhibitory role in mouse placental development.
Data show that overexpression of manganese superoxide dismutase (MnSOD (show SOD2 Proteins)) increased the expression of aquaporin-1 (AQP1)
AQP1 deficiency delays long-term ischemia-reperfusion resolution, partly through repressing angiogenesis mediated by destabilizing HIF-2alpha (show EPAS1 Proteins).
The results demonstrate that the descending thin limb (DTL (show DTL Proteins)) of the intermediate loop is composed of type I epithelium and expresses both AQP1. The functional role of the DTL (show DTL Proteins) of the intermediate loop may be distinct from the short or long loops.
data suggest an important functional role of AQP1 in the pathobiology of hypoxia-induced pulmonary hypertension
Angiotensinogen (show AGT Proteins)-mediated downregulation of aquaporin 1 and Nrf2 (show NFE2L2 Proteins) signalling may play an important role in intrarenal renin (show REN Proteins)-angiotensin system-induced hypertension and kidney injury.
The results suggest an important role of AQP1-mediated plasma membrane water permeability in maternal-fetal fluid balance
AQP1 deficiency reduced microvascular permeability via the stabilization of HIF-1alpha (show HIF1A Proteins) levels in endothelial cells and decreased cellular apoptosis following MI.
These data provide the first direct experimental evidence for the functional relevance of endothelial AQP1 to the fluid transport in peritoneal dialysis
The expression of AQP1 and 3 is a manifestation of physiological adaptation of functionally mature chondrocytes able to respond to the change of their internal environment influenced by extracellular matrix.
function of AQP1 in tonicity response could be coupled or correlated to its function in band 3 (show SLC4A1 Proteins)-mediated CO2/HCO3(-) exchange
Data show that the expression of aquaporin (AQP) 1, AQP3, AQP5, epithelial Na+ channel (ENaC) and sodium potassium ATPase (Na-K-ATPase) are altered in patients with acute respiratory failure (ARF) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.
The native AQP1 gene, normally latent in human salivary gland cells, can be activated by both promoter-independent artificial transcription and epigenetic editing of the promoter.
We demonstrated that AQP1-like immunoreactivity and expression are significantly increased in plaques of Peyronie's disease patients Vs controls, implying that AQP1 overexpression might be the consequence of a localized maladaptive response of the connective tissue to repeated mechanical trauma
AQP-1 overexpression is associated with prostate cancer progression.
Study provides evidence that Mef2c (show MEF2C Proteins) cooperated with Sp1 (show PSG1 Proteins) to activate human AQP1 transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells indicating that AQP1 is a direct target of Mef2c (show MEF2C Proteins) in regulating angiogenesis and vasculogenesis of endothelial cells.
AQP1 was overexpressed in cystic cholangiocytes of patients with polycystic liver disease. A tendency of increased AQP1 protein expression in correlation with the cyst size was also found.
Aquaporin1 overexpression restored anti-cell proliferation and metastatic effect of si-Gli1 (show GLI1 Proteins).
Aquaporin-1 significantly contributes to hydrostatic pressure-driven water transport across aortic endothelial monolayers in culture.
Comparisons of free-energy and interaction-energy profiles for water conduction between AQP0 and AQP1 indicate that this interruption of the water chain causes a huge energy barrier opposing water translocation through AQP0.
Data present a detailed comparison between the cryo-electron microscopy and X-ray crystallography model structures of the human and bovine water channel aquaporin-1 (AQP1).
AQP1, AQP2, and AQP3, and V2R expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity
These results suggest a participation of steroid hormones (P4 and E2), AA derivatives and cAMP in controlling the expression of AQP1 and AQP5 (show AQP5 Proteins) as well as the distribution of AQP5 (show AQP5 Proteins) in the uterine tissue of pregnant gilts during placentation (Days 30 - 32 of gestation).
up-regulated by progesterone, estradiol, arachidonic acid, forskolin, and cyclic AMP (show TMPRSS5 Proteins) in the uterus during the embryo implantation period
AQP1 and 5 seem to be crucial for follicular development in pigs
expressed in the endothelial cells of peri (show PLIN1 Proteins)-ovarian vascular complex and may modulate hormonal regulation of reproductive organs
pAQP1 is the first porcine aquaporin that can be molecularly identified. Its distribution in epithelium and endothelium of digestive organs suggests a role of channel-mediated water transport in fluid secretion/absorption in the digestive function system.
Several subtypes of the AQPs (AQP1, 5, and 9) are involved in regulation of water homeostasis in the reproductive system of gilts.
The study results suggest that VACM-1 may regulate endothelial AQP1 concentration both in vivo and in vitro.
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
, aquaporin 1
, delayed early response protein 2
, growth factor-induced delayed early response protein
, water channel protein for red blood cells and kidney proximal tubule
, Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP))
, Colton blood group
, aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)
, channel-like integral membrane protein, 28-kDa
, urine water channel
, water channel protein CHIP29
, aquaporin 1 (channel-forming integral protein, 28kDa)
, water channel aquaporin-1