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Upregulation of ARF3 is associated with ovarian cancer.
observations indicate that Arf1 (show ARF1 Proteins) and Arf3 as well as Arf6 (show ARF6 Proteins) play important roles in cytokinesis.
activated ARF3 is associated with Unc93B1 and TLR9 (show TLR9 Proteins), suggesting that ARF3 conducts TLR9 (show TLR9 Proteins) trafficking by forming the TLR9 (show TLR9 Proteins)-Unc93B1-ARF3 complex.
ARF1+ARF3 are required for integrity of recycling endosomes but are involved in distinct transport pathways: they are required for the transferrin (show Tf Proteins) recycling pathway from endosomes to the plasma membrane.
ARF1 (show ARF1 Proteins) and ARF3 are redundantly required for the integrity of recycling endosomes
These results suggest that Arf3 plays a unique function at the trans-Golgi network that likely involves recruitment by a specific receptor.
expression and subcellular redistribution by heregulin (show NRG1 Proteins)
Analysis of ta-siRNA synthesis mutants and mutated ARF3-overexpressing plants that escape the tasiRNA-ARF target indicated that self-pollination was hampered by short stamens in plants under drought and high-salinity stress.
ARF3 is a direct target of AP2 (show TFAP2A Proteins) and partially mediates AP2 (show TFAP2A Proteins)'s function in floral meristem determinacy.ARF3 integrates the functions of AGAMOUS and APETALA2 in floral meristem determinacy.
ARF3 mediates the auxin response during de novo shoot regeneration.
AS1 binds the ETT promoter. An upstream region of ETT directs transcriptional repression by AS1 and AS2. AS2 requires AS1 to regulate ETT expression directly.
ARL1(AT2G24765) is associated with the localization of peripheral golgins to the plant Golgi apparatus.
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
ADP-ribosylation factor 3
, small GTP binding protein
, liver regeneration-related protein LRRG202