Browse our PLA2G2D Proteins (PLA2G2D)

Full name:
phospholipase A2, Group IID Proteins (PLA2G2D)
On are 7 phospholipase A2, Group IID (PLA2G2D) Proteins from 5 different suppliers available. Additionally we are shipping PLA2G2D Antibodies (51) and PLA2G2D Kits (17) and many more products for this protein. A total of 78 PLA2G2D products are currently listed.
list all proteins Gene Name GeneID UniProt
PLA2G2D 26279 Q9UNK4
PLA2G2D 18782 Q9WVF6
PLA2G2D 298579  

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PLA2G2D Proteins (PLA2G2D) by Origin

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Human phospholipase A2, Group IID (PLA2G2D) interaction partners

  1. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

  2. sPLA(2)-IID is present at the head and midpiece in the human sperm, and its activation seems to be involved in acrosomal exocytosis.

  3. phospholipid bilayer permeabilization by the hsPLA2GIID is independent of catalytic activity.

  4. The Gly80Ser polymorphism may be associated with the body weight loss seen in chronic obstructive pulmonary disease patients. PLA2G2D-Ser (show SIGLEC1 Proteins) enhances the expression of IL-6 (show IL6 Proteins) and IL-8 (show IL8 Proteins) compared with PLA2G2D-Gly.

  5. TNF-alpha (show TNF Proteins) & IFN-gamma (show IFNG Proteins) induce gene expression of a novel secretory PLA(2 (show YWHAZ Proteins))IIDin human airway epithelial cells. The possibility that it is involved in cytokine-mediated inflammation in the respiratory tract is inferred.

  6. The GIID sPLA2 is clustered on human chromosome 1 and is differentially expressed in tissues, suggesting it has unique function.

  7. overexpression of human secretory phospholipase A2 group IIA leads to an enhanced delivery of cholesterol from phospholipolysed lipoproteins to the liver

  8. These results suggest that sPLA2-IID may be one of the susceptibility genes that contribute to body weight loss in patients with COPD (show ARCN1 Proteins).

  9. lipopolysaccharides inhibit interferon gamma-induced gene expression of secretory phospholipase A2 type IID in human monocyte-derived macrophages

  10. The distribution pattern of sPLA2S in intact spermatozoa might be an additional parameter for evaluating sperm quality

Mouse (Murine) phospholipase A2, Group IID (PLA2G2D) interaction partners

  1. these results underscore a general role of sPLA2-IID as an immunosuppressive sPLA2 (show PLA2G2A Proteins) that allows the microenvironmental lipid balance toward an anti-inflammatory state, exerting beneficial or detrimental impact depending upon distinct pathophysiological contexts in inflammation and cancer.

  2. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

  3. PLA2G2D in the LNs contributed to mobilization of a pool of polyunsaturated fatty acids.

PLA2G2D Protein Profile

Protein Summary

This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PLA2G2D

  • phospholipase A2, group IID (PLA2G2D)
  • phospholipase A2, group IID (Pla2g2d)
  • mGIID protein
  • PLA2IID protein
  • sPLA2-IID protein
  • sPLA2S protein
  • Splash protein

Protein level used designations for PLA2G2D

GIID sPLA2 , group IID secretory phospholipase A2 , phosphatidylcholine 2-acylhydrolase 2D , secretory phospholipase A2s , secretory-type PLA, stroma-associated homolog , PLA2IID , sPLA2-IID

26279 Homo sapiens
18782 Mus musculus
298579 Rattus norvegicus
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