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expression of PLA2s (show PLA2G2A Proteins)-IIE and -V correlates with the development of calcification as well as the expression of pro-osteogenic molecules in human aortic valves
sPLA(2 (show PLA2G2A Proteins)) -IIE regulates lipolysis in adipocytes, likely through the ERK (show EPHB2 Proteins)/HSL (show LIPE Proteins) signaling pathway
Single-nucleotide polymorphism in PLA2G2E gene is associated with ulcerative colitis.
promotes stimulus-induced arachidonic acid release and prostaglandin (PG) production similar to those elicited by HSPG (show HSPG2 Proteins)-dependent sPLA(2 (show PLA2G2A Proteins))s, suggesting that this enzyme plays a role in the inflammatory process.
PLA2G2E altered minor lipoprotein phospholipids, phosphatidylserine and phosphatidylethanolamine, and moderately facilitated lipid accumulation in adipose tissue and liver.
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.
phospholipase A2, group IIE
, group IIE secretory phospholipase A2
, phosphatidylcholine 2-acylhydrolase 2E
, GIIE sPLA2