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Browse our PLAUR Proteins (PLAUR)

Full name:
Plasminogen Activator, Urokinase Receptor Proteins (PLAUR)
On www.antibodies-online.com are 36 Plasminogen Activator, Urokinase Receptor (PLAUR) Proteins from 13 different suppliers available. Additionally we are shipping PLAUR Antibodies (174) and PLAUR Kits (54) and many more products for this protein. A total of 280 PLAUR products are currently listed.
Synonyms:
CD87, Par, PLAUR, Plaur3, U-PAR, UPAR, uPAR-2, uPAR-3, URKR
list all proteins Gene Name GeneID UniProt
PLAUR 18793 P35456
PLAUR 5329 Q03405
PLAUR 50692 P49616

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PLAUR Proteins (PLAUR) by Origin

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Top referenced PLAUR Proteins

  1. Human PLAUR Primary Antibody for FACS, IF - ABIN2666525 : Vincenza Carriero, Franco, Vocca, Alfano, Longanesi-Cattani, Bifulco, Mancini, Caputi, Stoppelli: Structure, function and antagonists of urokinase-type plasminogen activator. in Frontiers in bioscience (Landmark edition) 2009 (PubMed)
    Show all 8 references for ABIN2666525

  2. Human PLAUR Primary Antibody for - ABIN2181889 : Huai, Mazar, Kuo, Parry, Shaw, Callahan, Li, Yuan, Bian, Chen, Furie, Furie, Cines, Huang: Structure of human urokinase plasminogen activator in complex with its receptor. in Science (New York, N.Y.) 2006 (PubMed)
    Show all 4 references for ABIN2181889

  3. Mouse (Murine) PLAUR Primary Antibody for - ABIN2007425 : Dear, Medcalf: The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule. in European journal of biochemistry / FEBS 1998 (PubMed)
    Show all 3 references for ABIN2007425

  4. Mouse (Murine) PLAUR Primary Antibody for - ABIN2007428 : Suh, Nerlov, Danø, Degen: The murine urokinase-type plasminogen activator receptor gene. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN2007428

More Proteins for PLAUR Interaction Partners

Mouse (Murine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. Significance of the urokinase-type plasminogen activator (show PLAU Proteins) and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models.

  2. Findings indicate a significant correlation of uPAR cleavage with breast cancer progression, but the precise biological consequence(s) of the cleavage or the cleavage products still remains to be elucidated.

  3. interaction of full-length suPAR with alphavbeta3 integrin expressed on podocytes results in down-modulation of nephrin (show NPHS1 Proteins) that may affect kidney functionality in different human pathologies characterized by increased concentration of suPAR.

  4. In an in vivo murine angiogenesis model uPAR-deficient PTEN heterozygous animals increased the impaired angiogenic phenotype of uPAR knockout mice and were able to reverse the high invasive potential of PTEN heterozygotes.

  5. uPAR contributes to macrophage driven atherosclerotic lesion formation.

  6. we have firstly shown a fundamental mechanism of urokinase system(uPa (show PLAU Proteins) and uPAR)-dependent regulation of the trajectory of growth and branching of blood vessels in early embryogenesis and in adults during the repair/regeneration of tissues.

  7. our data show that uPAR is required for efficient skin tumor formation

  8. Tumours with high levels of uPAR, as well as cells invading leiomyoma tissue with up-regulated uPAR expression, all displayed enhanced activity of gelatinolytic enzymes.

  9. deficiency of uPAR and PSMD6 (show PSMD6 Proteins) delays DNA repair and leads to decreased cell survival.

  10. beta-elemene downregulates expression of uPA (show PLAU Proteins), uPAR, MMP-2 (show MMP2 Proteins), and MMP-9 (show MMP9 Proteins) in a murine intraocular melanoma model

Human Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. our study indicates that suPAR increases in patients with AML (show RUNX1 Proteins) and this situation is associated with poorer survival. suPAR can thus be used as a diagnostic and prognostic biomarker in AML (show RUNX1 Proteins) and may help in the developing of specific therapeutic targets.

  2. urokinase plasminogen activator receptor has a role in incidence of venous thromboembolism

  3. Our study implies that both soluble UPAR and advanced echocardiography are useful diagnostic tools for identifying patients with diabetes at risk of future clinical heart disease

  4. The effect of LIF (show LIF Proteins) and uPAR on trophoblast migration and invasion was mediated by PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling pathway.

  5. Soluble urokinase plasminogen (show PLG Proteins) activation receptor (suPAR) is an emerging new biomarker for prognosticating cardiovascular disease

  6. we review the human and mouse Ly6/uPAR family gene and protein structure and genomic organization, expression, functions, and evolution, and introduce new names for novel family members

  7. Report presence of urokinase-type plasminogen activator receptor in seminal plasma, focusing on its interesting role as reliable and sensitive marker of inflammation for the differential diagnosis of male accessory gland inflammation.

  8. uPAR expression is higher in normal pregnant women than that in patients with threatened abortion. uPAR promotes trophoblast migration and invasion during embryo implantation as well as plays a role in trophoblast differentiation into syntrophoblasts.

  9. This study examines the complexes of PAI-1 (show SERPINE1 Proteins) with tissue-type and urokinase-type plasminogen activator (show PLAU Proteins) and vitronectin (show VTN Proteins) revealed by changes in the conformation and dynamics of the reactive center loop.

  10. results show that cleaved uPAR forms are significantly increased in patients with advanced prostate cancer.

Cow (Bovine) Plasminogen Activator, Urokinase Receptor (PLAUR) interaction partners

  1. Data show that urokinase-type plasminogen activator (uPA (show PLAU Proteins)) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA (show PLAU Proteins) receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1 (show SERPINE1 Proteins)) are expressed in both the cumulus cells and the immature and in vitro matured oocytes.

  2. uPA (show PLAU Proteins)/uPAR binding is involved in signaling pathways that activate transcription factors that regulate the synthesis of molecules concerned with the arrangement of a particular oviductal microenvironment.

  3. Data indicate that superoxide dismutase (SOD) inhibited high glucose (HG)-induced expression of uPAR and VEGF in bovine retinal microvascular endothelial cell (REC).

  4. These data indicated that E. coli LPS (show IRF6 Proteins) led to an increase in u-PA (show PLAU Proteins) activity and RNA expression of u-PA (show PLAU Proteins) and u-PAR in BME-UV1 cells, thus strengthening the role of the PA system during pathological processes.

  5. the interaction between uPAR and Man-6-P/IGF2R (show IGF2R Proteins) is a low percentage binding event and that suPAR and full-length uPAR bind the Man-6-P/IGF2R (show IGF2R Proteins) by different mechanisms.

PLAUR Protein Profile

Protein Summary

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Alternative names and synonyms associated with PLAUR

  • plasminogen activator, urokinase receptor (PLAUR)
  • plasminogen activator, urokinase receptor (Plaur)
  • urokinase-type plasminogen activator receptor (LOC100101584)
  • CD87 protein
  • Par protein
  • PLAUR protein
  • Plaur3 protein
  • U-PAR protein
  • UPAR protein
  • uPAR-2 protein
  • uPAR-3 protein
  • URKR protein

Protein level used designations for PLAUR

urokinase plasminogen activator surface receptor , plasminogen activator, urokinase receptor , urokinase plasminogen activator receptor , urokinase-type plasminogen activator receptor , monocyte activation antigen Mo3 , u-plasminogen activator receptor form 2 , urokinase-type plasminogen activator (uPA) receptor , U-PAR , uPAR , plasminogen activator urokinase receptor 3 , urinary plasminogen activator receptor 2 , urinary plasminogen activator receptor 3

GENE ID SPECIES
100033904 Equus caballus
100302564 Ovis aries
18793 Mus musculus
5329 Homo sapiens
476446 Canis lupus familiaris
281983 Bos taurus
50692 Rattus norvegicus
450103 Pan troglodytes
100101584 Oryctolagus cuniculus
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